FR2981352B1 - Procede de synthese de proteines - Google Patents

Procede de synthese de proteines

Info

Publication number
FR2981352B1
FR2981352B1 FR1159348A FR1159348A FR2981352B1 FR 2981352 B1 FR2981352 B1 FR 2981352B1 FR 1159348 A FR1159348 A FR 1159348A FR 1159348 A FR1159348 A FR 1159348A FR 2981352 B1 FR2981352 B1 FR 2981352B1
Authority
FR
France
Prior art keywords
protein synthesis
protein
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1159348A
Other languages
English (en)
French (fr)
Other versions
FR2981352A1 (fr
Inventor
Oleg Melnyk
Laurent Raibaut
Vincent Aucagne
Agnes Delmas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1159348A priority Critical patent/FR2981352B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to PCT/EP2012/070454 priority patent/WO2013057084A1/fr
Priority to CA2852833A priority patent/CA2852833A1/fr
Priority to ES12772951T priority patent/ES2702786T3/es
Priority to SG11201401540WA priority patent/SG11201401540WA/en
Priority to IN2870CHN2014 priority patent/IN2014CN02870A/en
Priority to EP12772951.5A priority patent/EP2768842B1/fr
Priority to US14/352,155 priority patent/US9206224B2/en
Priority to JP2014536201A priority patent/JP6321542B2/ja
Priority to CN201280062427.3A priority patent/CN103998455B/zh
Publication of FR2981352A1 publication Critical patent/FR2981352A1/fr
Application granted granted Critical
Publication of FR2981352B1 publication Critical patent/FR2981352B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/34—Introducing sulfur atoms or sulfur-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FR1159348A 2011-10-17 2011-10-17 Procede de synthese de proteines Expired - Fee Related FR2981352B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR1159348A FR2981352B1 (fr) 2011-10-17 2011-10-17 Procede de synthese de proteines
JP2014536201A JP6321542B2 (ja) 2011-10-17 2012-10-16 タンパク質の合成方法
ES12772951T ES2702786T3 (es) 2011-10-17 2012-10-16 Procedimiento de síntesis de proteínas
SG11201401540WA SG11201401540WA (en) 2011-10-17 2012-10-16 Method for synthesizing proteins
IN2870CHN2014 IN2014CN02870A (enExample) 2011-10-17 2012-10-16
EP12772951.5A EP2768842B1 (fr) 2011-10-17 2012-10-16 Procédé de synthèse de protéines
PCT/EP2012/070454 WO2013057084A1 (fr) 2011-10-17 2012-10-16 Procede de synthese de proteines
CA2852833A CA2852833A1 (fr) 2011-10-17 2012-10-16 Procede de synthese de proteines
CN201280062427.3A CN103998455B (zh) 2011-10-17 2012-10-16 合成蛋白质的方法
US14/352,155 US9206224B2 (en) 2011-10-17 2012-10-16 Method for synthesizing proteins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1159348A FR2981352B1 (fr) 2011-10-17 2011-10-17 Procede de synthese de proteines

Publications (2)

Publication Number Publication Date
FR2981352A1 FR2981352A1 (fr) 2013-04-19
FR2981352B1 true FR2981352B1 (fr) 2015-07-03

Family

ID=47022687

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1159348A Expired - Fee Related FR2981352B1 (fr) 2011-10-17 2011-10-17 Procede de synthese de proteines

Country Status (10)

Country Link
US (1) US9206224B2 (enExample)
EP (1) EP2768842B1 (enExample)
JP (1) JP6321542B2 (enExample)
CN (1) CN103998455B (enExample)
CA (1) CA2852833A1 (enExample)
ES (1) ES2702786T3 (enExample)
FR (1) FR2981352B1 (enExample)
IN (1) IN2014CN02870A (enExample)
SG (1) SG11201401540WA (enExample)
WO (1) WO2013057084A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2971509B1 (fr) * 2011-02-16 2013-02-22 Centre Nat Rech Scient Procede de preparation de peptides par assemblage de multiples fragments peptidiques
BR112016000585A2 (pt) * 2013-07-11 2018-03-20 Novartis Ag modificações quimioenzimáticas sítio-específicas de proteína
NL2027769B1 (en) * 2021-03-18 2022-09-29 Univ Delft Tech C-terminal peptide modification

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT832096E (pt) 1995-05-04 2002-01-30 Scripps Research Inst Sintese de proteinas atraves de ligacao quimica nativa
JP4358307B2 (ja) 1996-12-24 2009-11-04 ザ スクリップス リサーチ インスティテュート 一般的化学結合
EP1001968B1 (en) * 1997-06-13 2004-12-22 Gryphon Therapeutics, Inc. Solid phase native chemical ligation of unprotected or n-terminal cysteine protected peptides in aqueous solution
US6570040B2 (en) 2000-03-16 2003-05-27 The Regents Of The University Of California Chemoselective ligation
AU6153001A (en) 2000-05-12 2001-11-26 Wisconsin Alumni Res Found Ligation method and reagents to form an amide bond
WO2003042235A2 (en) 2001-11-14 2003-05-22 Geneprot, Inc. Extended native chemical ligation of three or more peptide fragments
JP2008529969A (ja) * 2004-10-26 2008-08-07 ロンザ ア−ゲ− 固相合成におけるｓ−アルキル−スルフェニル保護基
CA2597490A1 (en) * 2005-02-11 2006-08-17 Merck Patent Gesellschaft Mit Beschraenkter Haftung Solid-phase oligosaccharide tagging: a technique for manipulation of immobilized carbohydrates
US7667076B2 (en) 2005-09-14 2010-02-23 Regents Of The University Of California Amide forming chemical ligation
FR2952058B1 (fr) * 2009-10-29 2013-10-04 Centre Nat Rech Scient Procede de ligation native de polypeptides
EP2501711B1 (en) 2009-11-16 2014-01-08 Centre National De La Recherche Scientifique CNRS Compounds and methods for purifying peptides produced by solid phase peptide synthesis

Also Published As

Publication number Publication date
JP6321542B2 (ja) 2018-05-09
CN103998455B (zh) 2018-05-29
US20140256879A1 (en) 2014-09-11
ES2702786T3 (es) 2019-03-05
FR2981352A1 (fr) 2013-04-19
WO2013057084A1 (fr) 2013-04-25
EP2768842B1 (fr) 2018-07-25
CN103998455A (zh) 2014-08-20
IN2014CN02870A (enExample) 2015-07-03
CA2852833A1 (fr) 2013-04-25
JP2014532075A (ja) 2014-12-04
EP2768842A1 (fr) 2014-08-27
SG11201401540WA (en) 2014-06-27
US9206224B2 (en) 2015-12-08

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Effective date: 20200910