FR2932480B1 - Phenyl-alkyl-piperazines ayant une activite modulatrice du tnf - Google Patents
Phenyl-alkyl-piperazines ayant une activite modulatrice du tnfInfo
- Publication number
- FR2932480B1 FR2932480B1 FR0803337A FR0803337A FR2932480B1 FR 2932480 B1 FR2932480 B1 FR 2932480B1 FR 0803337 A FR0803337 A FR 0803337A FR 0803337 A FR0803337 A FR 0803337A FR 2932480 B1 FR2932480 B1 FR 2932480B1
- Authority
- FR
- France
- Prior art keywords
- piperazines
- phenyl
- alkyl
- modulating activity
- tnf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (26)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0803337A FR2932480B1 (fr) | 2008-06-16 | 2008-06-16 | Phenyl-alkyl-piperazines ayant une activite modulatrice du tnf |
JO2009205A JO2857B1 (en) | 2008-06-16 | 2009-06-04 | Vinyl pipers with modified activity of tumor-resistant TNF |
ARP090102132A AR072120A1 (es) | 2008-06-16 | 2009-06-12 | Fenil-alquil-piperazinas que tienen actividad moduladora de tnf, un proceso de preparacion del compuesto, una composicion farmaceutica que lo contiene, un medicamento en base al compuesto y la utilizacion del compuesto para preparar un medicamento |
ES09766076T ES2433218T3 (es) | 2008-06-16 | 2009-06-16 | Fenil-alquil piperazinas que tienen una actividad moduladora de TNF |
EP09766076.5A EP2313384B1 (fr) | 2008-06-16 | 2009-06-16 | Phenyl-alkyl piperazines ayant une activite modulatrice du tnf |
UY0001031902A UY31902A (es) | 2008-06-16 | 2009-06-16 | Fenil-alquil-piperazinas que tienen actividad moduñadoras de tnf |
AU2009261783A AU2009261783B2 (en) | 2008-06-16 | 2009-06-16 | Phenyl-alkyl piperazines having a modulating activity of TNF |
DK09766076.5T DK2313384T3 (da) | 2008-06-16 | 2009-06-16 | Phenyl-alkylpiperaziner med tnf-modulerende aktivitet |
PL09766076T PL2313384T3 (pl) | 2008-06-16 | 2009-06-16 | Fenyloalkilopiperazyny wykazujące aktywność modulującą tnf |
KR1020107028188A KR20110028452A (ko) | 2008-06-16 | 2009-06-16 | Tnf의 조절 활성을 가지는 페닐-알킬 피페라진 |
JP2011514097A JP5536050B2 (ja) | 2008-06-16 | 2009-06-16 | Tnfの調節活性を有するフェニル−アルキルピペラジン |
CN2009801315519A CN102123995A (zh) | 2008-06-16 | 2009-06-16 | 具有tnf调节活性的苯基-烷基哌嗪 |
RU2011101396/04A RU2512567C2 (ru) | 2008-06-16 | 2009-06-16 | Фенилалкилпиперазины, модулирующие активность tnf |
PCT/FR2009/051138 WO2009153514A1 (fr) | 2008-06-16 | 2009-06-16 | Phenyl-alkyl piperazines ayant une activite modulatrice du tnf |
SI200930774T SI2313384T1 (sl) | 2008-06-16 | 2009-06-16 | Fenil-alkil piperazini, ki imajo aktivnost moduliranja TNF |
CN201510688427.XA CN105198803A (zh) | 2008-06-16 | 2009-06-16 | 具有tnf调节活性的苯基-烷基哌嗪 |
CA2727911A CA2727911C (fr) | 2008-06-16 | 2009-06-16 | Phenyl-alkyl-piperazines ayant une activite modulatrice du tnf |
TW098120169A TW201002687A (en) | 2008-06-16 | 2009-06-16 | Phenyl-alkylpiperazines with TNF-modulating activity |
PT97660765T PT2313384E (pt) | 2008-06-16 | 2009-06-16 | Fenil-alquil-piperazinas tendo uma actividade moduladora do tnf |
MYPI20105969 MY153051A (en) | 2008-06-16 | 2009-06-16 | Phenyl-alkyl piperazines having a modulating activity of tnf |
MX2010013947A MX2010013947A (es) | 2008-06-16 | 2009-06-16 | Fenil-alquil-piperazinas que tienen actividad moduladora de tnf. |
BRPI0914815A BRPI0914815A2 (pt) | 2008-06-16 | 2009-06-16 | fenil-alquil-piperazinas com atividade moduladora de tnf |
IL209944A IL209944A (en) | 2008-06-16 | 2010-12-12 | Phenyl-Alkyl Paprazine Compounds, Process for Preparation, Pharmaceutical Composition and Drug Containing them |
US12/970,047 US8153637B2 (en) | 2008-06-16 | 2010-12-16 | Phenyl-alkyl piperazines having TNF-modulating activity, preparation method, and therapeutic use thereof |
CY20131101052T CY1114823T1 (el) | 2008-06-16 | 2013-11-25 | Φαινυλ-αλκυλ πιπεραζινες οι οποιες διαθετουν μια ρυθμιστικη δραστηριοτητα του τνf |
HRP20131183AT HRP20131183T1 (hr) | 2008-06-16 | 2013-12-12 | Fenilalkilpiperazini s aktivnošä†u modulatora tnf |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0803337A FR2932480B1 (fr) | 2008-06-16 | 2008-06-16 | Phenyl-alkyl-piperazines ayant une activite modulatrice du tnf |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2932480A1 FR2932480A1 (fr) | 2009-12-18 |
FR2932480B1 true FR2932480B1 (fr) | 2010-11-12 |
Family
ID=40079673
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0803337A Expired - Fee Related FR2932480B1 (fr) | 2008-06-16 | 2008-06-16 | Phenyl-alkyl-piperazines ayant une activite modulatrice du tnf |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2932480B1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO2857B1 (en) * | 2008-06-16 | 2015-03-15 | سانوفي أفينتس | Vinyl pipers with modified activity of tumor-resistant TNF |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001072660A (ja) * | 1999-09-08 | 2001-03-21 | Welfide Corp | TNF−α産生抑制剤および/またはIL−10産生促進剤 |
EP1587473A4 (fr) * | 2002-12-27 | 2008-08-13 | Novartis Vaccines & Diagnostic | Thiosemicarbazones antiviraux et immunostimulants |
-
2008
- 2008-06-16 FR FR0803337A patent/FR2932480B1/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2932480A1 (fr) | 2009-12-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |
Effective date: 20160229 |