FR2931479B1 - Nouveaux derives de quinoleines 2-substituees et un procede pour leur preparation - Google Patents

Nouveaux derives de quinoleines 2-substituees et un procede pour leur preparation

Info

Publication number
FR2931479B1
FR2931479B1 FR0802745A FR0802745A FR2931479B1 FR 2931479 B1 FR2931479 B1 FR 2931479B1 FR 0802745 A FR0802745 A FR 0802745A FR 0802745 A FR0802745 A FR 0802745A FR 2931479 B1 FR2931479 B1 FR 2931479B1
Authority
FR
France
Prior art keywords
novel
preparation
quinoline derivatives
substituted quinoline
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0802745A
Other languages
English (en)
Other versions
FR2931479A1 (fr
Inventor
Alain Fournet
Bernardin Akagah
Bruno Figadere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ALPHA CHIMICA
I R D
Original Assignee
ALPHA CHIMICA
I R D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ALPHA CHIMICA, I R D filed Critical ALPHA CHIMICA
Priority to FR0802745A priority Critical patent/FR2931479B1/fr
Priority to EP09761869A priority patent/EP2291381A1/fr
Priority to PCT/FR2009/000573 priority patent/WO2009150318A1/fr
Priority to US12/993,102 priority patent/US20120225903A1/en
Priority to BRPI0908627A priority patent/BRPI0908627A2/pt
Publication of FR2931479A1 publication Critical patent/FR2931479A1/fr
Application granted granted Critical
Publication of FR2931479B1 publication Critical patent/FR2931479B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14Radicals substituted by oxygen atoms
FR0802745A 2008-05-20 2008-05-20 Nouveaux derives de quinoleines 2-substituees et un procede pour leur preparation Expired - Fee Related FR2931479B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0802745A FR2931479B1 (fr) 2008-05-20 2008-05-20 Nouveaux derives de quinoleines 2-substituees et un procede pour leur preparation
EP09761869A EP2291381A1 (fr) 2008-05-20 2009-05-15 Nouveaux derives de quinoleines 2-substituees et un procede pour leur preparation
PCT/FR2009/000573 WO2009150318A1 (fr) 2008-05-20 2009-05-15 Nouveaux derives de quinoleines 2-substituees et un procede pour leur preparation
US12/993,102 US20120225903A1 (en) 2008-05-20 2009-05-15 Novel 2-Substituted Quinoline Derivatives, And Method For Preparing Same
BRPI0908627A BRPI0908627A2 (pt) 2008-05-20 2009-05-15 processo para se produzir moléculas escolhidas entre as das fórmulas (iia), (iib), (iic) e (iii), molécula de fórmula (iia), (iib), (iic), (iii), (iv) e (v), processo para produzir uma molécula que corresponde à formula (v), (vi), ou (vii), moléculas, composição farmacêutica e uso de uma composição

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0802745A FR2931479B1 (fr) 2008-05-20 2008-05-20 Nouveaux derives de quinoleines 2-substituees et un procede pour leur preparation

Publications (2)

Publication Number Publication Date
FR2931479A1 FR2931479A1 (fr) 2009-11-27
FR2931479B1 true FR2931479B1 (fr) 2012-12-07

Family

ID=40149587

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0802745A Expired - Fee Related FR2931479B1 (fr) 2008-05-20 2008-05-20 Nouveaux derives de quinoleines 2-substituees et un procede pour leur preparation

Country Status (5)

Country Link
US (1) US20120225903A1 (fr)
EP (1) EP2291381A1 (fr)
BR (1) BRPI0908627A2 (fr)
FR (1) FR2931479B1 (fr)
WO (1) WO2009150318A1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE282457C (fr) *
US4440771A (en) * 1982-02-12 1984-04-03 The United States Of America As Represented By The Secretary Of The Army 2-Acetyl quinoline thiosemicarbazones useful in treatment of gonorrhea, malaria or bacterial infections
FR2682107B1 (fr) * 1991-10-03 1995-04-21 Orstom Inst Fs Rech Scient Quinoleines 2-substituees pour le traitement des leishmanioses.
FR2819507B1 (fr) * 2001-01-17 2007-09-28 Inst Rech Developpement Ird Quinoleines substituees pour le traitement de co-infections a protozoaires et a retrovirus
EP1734939A4 (fr) * 2004-03-05 2010-06-30 Univ California Composes antiparasitaires et leurs procedes d'utilisation

Also Published As

Publication number Publication date
WO2009150318A1 (fr) 2009-12-17
EP2291381A1 (fr) 2011-03-09
US20120225903A1 (en) 2012-09-06
FR2931479A1 (fr) 2009-11-27
BRPI0908627A2 (pt) 2015-09-15

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Year of fee payment: 8

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Effective date: 20170131