FR2926817B1 - Derives d'uree de tetrahydroquinoxaline, leur preparation et leur application en therapeutique - Google Patents
Derives d'uree de tetrahydroquinoxaline, leur preparation et leur application en therapeutiqueInfo
- Publication number
- FR2926817B1 FR2926817B1 FR0800429A FR0800429A FR2926817B1 FR 2926817 B1 FR2926817 B1 FR 2926817B1 FR 0800429 A FR0800429 A FR 0800429A FR 0800429 A FR0800429 A FR 0800429A FR 2926817 B1 FR2926817 B1 FR 2926817B1
- Authority
- FR
- France
- Prior art keywords
- preparation
- therapeutic use
- urea derivatives
- tetrahydroquinoxaline
- tetrahydroquinoxaline urea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (26)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0800429A FR2926817B1 (fr) | 2008-01-28 | 2008-01-28 | Derives d'uree de tetrahydroquinoxaline, leur preparation et leur application en therapeutique |
TW098103125A TW200936136A (en) | 2008-01-28 | 2009-01-23 | Tetrahydroquinoxaline urea derivatives, their preparation and their therapeutic application |
ARP090100229A AR070255A1 (es) | 2008-01-28 | 2009-01-26 | Derivados de urea de tetrahidroquinoxalina, su preparacion, composiciones farmaceuticas que los contienen y su uso en la modulacion de la actividad de 11-beta hd1 (hidroxiesteroide deshidrogenasa de tipo 1) |
PE2009000105A PE20091323A1 (es) | 2008-01-28 | 2009-01-26 | Derivados de urea de tetrahidroquinoxalina, su preparacion y su aplicacion en terapeutica |
CN2009801113945A CN101981026A (zh) | 2008-01-28 | 2009-01-27 | 四氢喹喔啉脲衍生物、它们的制备及它们的治疗应用 |
KR1020107019130A KR20100111308A (ko) | 2008-01-28 | 2009-01-27 | 테트라히드로퀴녹살린 우레아의 유도체, 그의 제법 및 그의 치료학적 용도 |
MX2010008290A MX2010008290A (es) | 2008-01-28 | 2009-01-27 | Derivados de urea de tetrahidroquinoxalina, su preparacion y su aplicacion terapeutica. |
EP09720707.0A EP2238126B1 (fr) | 2008-01-28 | 2009-01-27 | Dérivés d'urée de tetrahydroquinoxaline, leur préparation et leur application en thérapeutique |
JP2010543545A JP2011510919A (ja) | 2008-01-28 | 2009-01-27 | テトラヒドロキノキサリン尿素誘導体、これらの調製、および治療的適用 |
CA2713367A CA2713367A1 (fr) | 2008-01-28 | 2009-01-27 | Derives d'uree de tetrahydroquinoxaline, leur preparation et leur application en therapeutique |
AU2009224546A AU2009224546B2 (en) | 2008-01-28 | 2009-01-27 | Derivatives of tetrahydroquinoxaline urea, preparation thereof and therapeutic application thereof |
PA20098813701A PA8813701A1 (es) | 2008-01-28 | 2009-01-27 | Derivados de urea de tetrahidroquinoxalina, su preparacion y su aplicacion en terapeutica |
EA201070895A EA201070895A1 (ru) | 2008-01-28 | 2009-01-27 | Карбамидные производные тетрагидрохиноксалина, их получение и их применение в терапии |
BRPI0906567-9A BRPI0906567A2 (pt) | 2008-01-28 | 2009-01-27 | Derivados de ureia de tetra-hidroquinoxalina, o respectivo preparo e a respectiva aplicação em terapêutica j |
PCT/FR2009/000083 WO2009112691A2 (fr) | 2008-01-28 | 2009-01-27 | Dérivés d'urée de tetrahydroquinoxaline, leur préparation et leur application en thérapeutique j |
UY031616A UY31616A1 (es) | 2008-01-28 | 2009-01-28 | Derivados de urea de tetrahidroquinoxalina, su preparación y su aplicación en terapéutica |
CL2009000173A CL2009000173A1 (es) | 2008-01-28 | 2009-01-28 | Compuestos derivados de urea-tetrahidroxiquinoxalina; procedimiento de preparacion; compuestos intermediarios; composicion farmaceutica; y uso para el tratamiento y la prevencion de la obesidad y la diabetes, resistencia a la insulina, sindrome metabolico, entre otros. |
EC2010010368A ECSP10010368A (es) | 2008-01-28 | 2010-07-23 | Derivados de urea de tetrahidroquinoxalina, su preparación |
IL207195A IL207195A (en) | 2008-01-28 | 2010-07-25 | Tetrahydroquinoxaline derivatives ore, their preparation and therapeutic application |
NI201000130A NI201000130A (es) | 2008-01-28 | 2010-07-26 | Derivados de urea de tetrahidroquinoxalina, su preparación y su aplicación en terapéutica. |
US12/843,124 US8211892B2 (en) | 2008-01-28 | 2010-07-26 | Tetrahydroquinoxaline urea derivatives |
DO2010000230A DOP2010000230A (es) | 2008-01-28 | 2010-07-27 | Derivados de urea de tetrahidroquinoxalina, su preparacion y su aplicacion en terapeutica |
CR11596A CR11596A (es) | 2008-01-28 | 2010-07-27 | Derivados de urea de tetrahidroquinoxalina, su preparacion y su aplicacion en terapeutica |
CO10092048A CO6290672A2 (es) | 2008-01-28 | 2010-07-28 | Derivados de urea de tetrahidroquinoxalina su preparacion aplicacion en terapeutica |
MA33110A MA32098B1 (fr) | 2008-01-28 | 2010-08-23 | Dérivés d'urée de tetrahydroquinoxaline, leur préparation et leur application en thérapeutique |
US13/483,710 US8530657B2 (en) | 2008-01-28 | 2012-05-30 | Substituted adamantanes and their therapeutic application |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0800429A FR2926817B1 (fr) | 2008-01-28 | 2008-01-28 | Derives d'uree de tetrahydroquinoxaline, leur preparation et leur application en therapeutique |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2926817A1 FR2926817A1 (fr) | 2009-07-31 |
FR2926817B1 true FR2926817B1 (fr) | 2010-02-26 |
Family
ID=39745213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0800429A Expired - Fee Related FR2926817B1 (fr) | 2008-01-28 | 2008-01-28 | Derives d'uree de tetrahydroquinoxaline, leur preparation et leur application en therapeutique |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2926817B1 (fr) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004056744A1 (fr) * | 2002-12-23 | 2004-07-08 | Janssen Pharmaceutica N.V. | Adamantyl acetamides utilises comme inhibiteurs de la hydroxysteroide deshydrogenase |
TW200811170A (en) * | 2006-06-27 | 2008-03-01 | Sanofi Aventis | Urea derivatives of tropane, their preparation and their therapeutic application |
-
2008
- 2008-01-28 FR FR0800429A patent/FR2926817B1/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2926817A1 (fr) | 2009-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PLFP | Fee payment |
Year of fee payment: 8 |
|
ST | Notification of lapse |
Effective date: 20160930 |