FR2910492B1 - Procede de preparation de bacteriophages modifies par insertion de sequences aleatoires dans les proteines de ciblage desdits bacteriophages - Google Patents
Procede de preparation de bacteriophages modifies par insertion de sequences aleatoires dans les proteines de ciblage desdits bacteriophagesInfo
- Publication number
- FR2910492B1 FR2910492B1 FR0655721A FR0655721A FR2910492B1 FR 2910492 B1 FR2910492 B1 FR 2910492B1 FR 0655721 A FR0655721 A FR 0655721A FR 0655721 A FR0655721 A FR 0655721A FR 2910492 B1 FR2910492 B1 FR 2910492B1
- Authority
- FR
- France
- Prior art keywords
- bacteriophages
- bacteriophage
- sequence
- bacteria
- randomly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241001515965 unidentified phage Species 0.000 title abstract 19
- 108090000623 proteins and genes Proteins 0.000 title abstract 12
- 230000008685 targeting Effects 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 6
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 238000003780 insertion Methods 0.000 title abstract 3
- 230000037431 insertion Effects 0.000 title abstract 3
- 241000894006 Bacteria Species 0.000 abstract 10
- 108091034117 Oligonucleotide Proteins 0.000 abstract 5
- 230000003321 amplification Effects 0.000 abstract 4
- 238000010276 construction Methods 0.000 abstract 4
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 4
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 230000001131 transforming effect Effects 0.000 abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000006801 homologous recombination Effects 0.000 abstract 1
- 238000002744 homologous recombination Methods 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10111—Myoviridae
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0655721A FR2910492B1 (fr) | 2006-12-20 | 2006-12-20 | Procede de preparation de bacteriophages modifies par insertion de sequences aleatoires dans les proteines de ciblage desdits bacteriophages |
| EP12192306.4A EP2653536A1 (fr) | 2006-12-20 | 2007-12-18 | Procédé de préparation de bactériophages modifiés par insertion de séquences aléatoires dans les protéines de ciblage desdits bactériophages. |
| JP2009542133A JP2010512774A (ja) | 2006-12-20 | 2007-12-18 | バクテリオファージのスクリーニング蛋白質へのランダム配列挿入により改変されたバクテリオファージの作製方法 |
| US12/520,789 US9315803B2 (en) | 2006-12-20 | 2007-12-18 | Method for the preparation of modified bacteriophages by insertion of random sequences in the targeting proteins of said bacteriophages |
| PCT/FR2007/002101 WO2008093009A2 (fr) | 2006-12-20 | 2007-12-18 | Procédé de préparation de bactériophages modifiés par insertion de séquences aléatoires dans les protéines de ciblage desdits bactériophages |
| EP07872388A EP2097516B1 (fr) | 2006-12-20 | 2007-12-18 | Procédé de préparation de bactériophages modifiés par insertion de séquences aléatoires dans les protéines de ciblage desdits bactériophages |
| AU2007346006A AU2007346006B2 (en) | 2006-12-20 | 2007-12-18 | Method for the preparation of modified bacteriophages by insertion of random sequences in the targeting proteins of said bacteriophages |
| CA2673579A CA2673579C (fr) | 2006-12-20 | 2007-12-18 | Procede de preparation de bacteriophages modifies par insertion de sequences aleatoires dans les proteines de ciblage desdits bacteriophages |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0655721A FR2910492B1 (fr) | 2006-12-20 | 2006-12-20 | Procede de preparation de bacteriophages modifies par insertion de sequences aleatoires dans les proteines de ciblage desdits bacteriophages |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2910492A1 FR2910492A1 (fr) | 2008-06-27 |
| FR2910492B1 true FR2910492B1 (fr) | 2013-02-15 |
Family
ID=38293109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR0655721A Expired - Fee Related FR2910492B1 (fr) | 2006-12-20 | 2006-12-20 | Procede de preparation de bacteriophages modifies par insertion de sequences aleatoires dans les proteines de ciblage desdits bacteriophages |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9315803B2 (https=) |
| EP (2) | EP2653536A1 (https=) |
| JP (1) | JP2010512774A (https=) |
| AU (1) | AU2007346006B2 (https=) |
| CA (1) | CA2673579C (https=) |
| FR (1) | FR2910492B1 (https=) |
| WO (1) | WO2008093009A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2945049B1 (fr) | 2009-04-30 | 2013-10-04 | Pherecydes Pharma | Modification du genome d'un bacteriophage lytique par immobilisation dudit bacteriophage dans sa bacterie hote |
| WO2017174809A1 (en) * | 2016-04-08 | 2017-10-12 | Phico Therapeutics Ltd | Modifying bacteriophage |
| CN112823206B (zh) * | 2018-10-17 | 2024-04-16 | 深圳华大生命科学研究院 | 从细菌全基因组序列中挖掘温和型噬菌体的方法、装置和存储介质 |
| US11724057B2 (en) | 2019-12-16 | 2023-08-15 | Melissa H. Egts | Protective, sanitary, securable nasal cannula cover |
| USD942002S1 (en) | 2019-12-16 | 2022-01-25 | Melissa H. Egts | Nasal cannula cover |
| DE102024113842A1 (de) * | 2024-05-16 | 2025-11-20 | bifa Umweltinstitut GmbH | Verfahren zur Verringerung der bakteriellen Last auf bzw. in einer Klimaanlage |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1270939B (it) * | 1993-05-11 | 1997-05-26 | Angeletti P Ist Richerche Bio | Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili. |
| US6203986B1 (en) * | 1998-10-22 | 2001-03-20 | Robert H. Singer | Visualization of RNA in living cells |
| CA2430501A1 (en) | 2000-01-11 | 2001-07-19 | Intralytix, Inc. | Method for produce sanitation using bacteriophages |
| ES2252263T3 (es) * | 2000-07-25 | 2006-05-16 | The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services | Bacteriofago que tiene una gama de hospedadores multiple. |
| GB0028130D0 (en) * | 2000-11-17 | 2001-01-03 | Phico Therapeutics Ltd | Polypeptide and uses thereof |
| WO2006066224A2 (en) * | 2004-12-14 | 2006-06-22 | Yale University | Virulence targeted antibiotics |
-
2006
- 2006-12-20 FR FR0655721A patent/FR2910492B1/fr not_active Expired - Fee Related
-
2007
- 2007-12-18 WO PCT/FR2007/002101 patent/WO2008093009A2/fr not_active Ceased
- 2007-12-18 CA CA2673579A patent/CA2673579C/fr active Active
- 2007-12-18 US US12/520,789 patent/US9315803B2/en not_active Expired - Fee Related
- 2007-12-18 EP EP12192306.4A patent/EP2653536A1/fr not_active Withdrawn
- 2007-12-18 JP JP2009542133A patent/JP2010512774A/ja active Pending
- 2007-12-18 AU AU2007346006A patent/AU2007346006B2/en not_active Ceased
- 2007-12-18 EP EP07872388A patent/EP2097516B1/fr not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010512774A (ja) | 2010-04-30 |
| US9315803B2 (en) | 2016-04-19 |
| WO2008093009A2 (fr) | 2008-08-07 |
| AU2007346006B2 (en) | 2013-08-29 |
| AU2007346006A1 (en) | 2008-08-07 |
| WO2008093009A8 (fr) | 2009-07-16 |
| CA2673579A1 (fr) | 2008-08-07 |
| WO2008093009A3 (fr) | 2009-02-12 |
| EP2097516A2 (fr) | 2009-09-09 |
| FR2910492A1 (fr) | 2008-06-27 |
| US20110027231A1 (en) | 2011-02-03 |
| CA2673579C (fr) | 2019-04-09 |
| EP2653536A1 (fr) | 2013-10-23 |
| EP2097516B1 (fr) | 2012-11-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TP | Transmission of property | ||
| PLFP | Fee payment |
Year of fee payment: 10 |
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| PLFP | Fee payment |
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| PLFP | Fee payment |
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| ST | Notification of lapse |
Effective date: 20240806 |