FR2901273B1 - Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant - Google Patents

Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant

Info

Publication number
FR2901273B1
FR2901273B1 FR0604496A FR0604496A FR2901273B1 FR 2901273 B1 FR2901273 B1 FR 2901273B1 FR 0604496 A FR0604496 A FR 0604496A FR 0604496 A FR0604496 A FR 0604496A FR 2901273 B1 FR2901273 B1 FR 2901273B1
Authority
FR
France
Prior art keywords
inhibitors
same
pharmaceutical compositions
compositions containing
papilloma virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0604496A
Other languages
English (en)
French (fr)
Other versions
FR2901273A1 (fr
Inventor
Marta Blumenfeld
Delphine Compere
Jean Michel Gauthier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anaconda Pharma SAS
Original Assignee
Anaconda Pharma SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0604496A priority Critical patent/FR2901273B1/fr
Application filed by Anaconda Pharma SAS filed Critical Anaconda Pharma SAS
Priority to ES07729287.8T priority patent/ES2436772T3/es
Priority to PT77292878T priority patent/PT2024350E/pt
Priority to CA2652469A priority patent/CA2652469C/fr
Priority to MX2008014771A priority patent/MX2008014771A/es
Priority to PCT/EP2007/054843 priority patent/WO2007135106A1/fr
Priority to US12/300,998 priority patent/US8207373B2/en
Priority to ARP070102162A priority patent/AR061027A1/es
Priority to DK07729287.8T priority patent/DK2024350T3/da
Priority to EP07729287.8A priority patent/EP2024350B1/fr
Priority to JP2009511485A priority patent/JP5399237B2/ja
Priority to BRPI0711208-4A priority patent/BRPI0711208A2/pt
Priority to CN2007800218616A priority patent/CN101466693B/zh
Publication of FR2901273A1 publication Critical patent/FR2901273A1/fr
Application granted granted Critical
Publication of FR2901273B1 publication Critical patent/FR2901273B1/fr
Priority to US13/466,530 priority patent/US9452991B2/en
Priority to US15/276,208 priority patent/US9974779B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR0604496A 2006-05-19 2006-05-19 Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant Expired - Fee Related FR2901273B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR0604496A FR2901273B1 (fr) 2006-05-19 2006-05-19 Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant
JP2009511485A JP5399237B2 (ja) 2006-05-19 2007-05-18 ヒトパピローマウイルス阻害剤としてのピペリジン誘導体
CA2652469A CA2652469C (fr) 2006-05-19 2007-05-18 Derives de piperidine comme inhibiteurs du virus du papillome humain
MX2008014771A MX2008014771A (es) 2006-05-19 2007-05-18 Derivados de piperidina como inhibidores del virus del papiloma humano.
PCT/EP2007/054843 WO2007135106A1 (fr) 2006-05-19 2007-05-18 Derives de piperidine comme inhibiteurs du virus du papillome humain
US12/300,998 US8207373B2 (en) 2006-05-19 2007-05-18 Benzoic acid derivatives as human papilloma virus inhibitors
ARP070102162A AR061027A1 (es) 2006-05-19 2007-05-18 Inhibidores del virus del papiloma humano y las composiciones farmaceuticas que los contienen
DK07729287.8T DK2024350T3 (da) 2006-05-19 2007-05-18 Piperidinderivater som inhibitorer af human papillomavirus
ES07729287.8T ES2436772T3 (es) 2006-05-19 2007-05-18 Derivados de piperidina como inhibidores del virus del papiloma humano
PT77292878T PT2024350E (pt) 2006-05-19 2007-05-18 Derivados de piperidina como inibidores don vírus do papiloma humano
BRPI0711208-4A BRPI0711208A2 (pt) 2006-05-19 2007-05-18 compostos, intermediários para a sìtemse dos compostos, processo, composição farmacêutica, uso de um composto e usos
CN2007800218616A CN101466693B (zh) 2006-05-19 2007-05-18 用作人乳头瘤病毒抑制剂的哌啶衍生物
EP07729287.8A EP2024350B1 (fr) 2006-05-19 2007-05-18 Derives de piperidine comme inhibiteurs du virus du papillome humain
US13/466,530 US9452991B2 (en) 2006-05-19 2012-05-08 Piperidine derivatives as human papilloma virus inhibitors
US15/276,208 US9974779B2 (en) 2006-05-19 2016-09-26 Piperidine derivatives as human papilloma virus inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0604496A FR2901273B1 (fr) 2006-05-19 2006-05-19 Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
FR2901273A1 FR2901273A1 (fr) 2007-11-23
FR2901273B1 true FR2901273B1 (fr) 2010-12-24

Family

ID=37575135

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0604496A Expired - Fee Related FR2901273B1 (fr) 2006-05-19 2006-05-19 Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant

Country Status (13)

Country Link
US (3) US8207373B2 (https=)
EP (1) EP2024350B1 (https=)
JP (1) JP5399237B2 (https=)
CN (1) CN101466693B (https=)
AR (1) AR061027A1 (https=)
BR (1) BRPI0711208A2 (https=)
CA (1) CA2652469C (https=)
DK (1) DK2024350T3 (https=)
ES (1) ES2436772T3 (https=)
FR (1) FR2901273B1 (https=)
MX (1) MX2008014771A (https=)
PT (1) PT2024350E (https=)
WO (1) WO2007135106A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2923825B1 (fr) 2007-11-20 2013-05-03 Anaconda Pharma Nouveaux inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant.
FR2990134B1 (fr) * 2012-05-07 2014-11-21 Anaconda Pharma Composition pharmaceutique d'un inhibiteur du virus du papillome
FR3000490B1 (fr) * 2012-12-27 2015-03-13 Anaconda Pharma Procede de synthese d'une hydrazine utile dans le traitement du virus du papillome
ES2796276T3 (es) * 2015-02-05 2020-11-26 Ab Science Compuestos con actividad antitumoral
WO2017009751A1 (en) 2015-07-15 2017-01-19 Pfizer Inc. Pyrimidine derivatives
CN105582083A (zh) * 2015-09-08 2016-05-18 石友爱 一种治疗鲍温样丘疹病的中药
US11555009B2 (en) 2017-03-02 2023-01-17 Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences 2-(substituted benzene matrix) aromatic formate FTO inhibitor, preparation method therefor, and applications thereof
CN109748903B (zh) * 2017-11-01 2021-08-10 北京协和制药二厂 吡法齐明的制备方法
EP3594206A1 (en) 2018-07-09 2020-01-15 Abivax Phenyl-n-quinoline derivatives for treating a rna virus infection
EP3594205A1 (en) 2018-07-09 2020-01-15 Abivax Phenyl-n-aryl derivatives for treating a rna virus infection
JP2020127293A (ja) * 2019-02-05 2020-08-20 ファナック株式会社 ロータコアの製造装置及びロータコアの製造方法、並びにロータ構造
CN110041223B (zh) * 2019-06-03 2021-10-22 西北师范大学 以肼类化合物为原料氧化合成偶氮类化合物的方法
CN114276273B (zh) * 2021-12-29 2024-06-21 维思普新材料（苏州）有限公司 一种基于四苯基肼类衍生物的有机电致发光材料及其电子器件

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292429A (en) * 1978-03-08 1981-09-29 Ciba-Geigy Corporation Imidazole urea and amido compounds
CA2367017C (en) * 1999-03-19 2009-05-26 Vertex Pharmaceuticals Incorporated Inhibitors of impdh enzyme
JP4550811B2 (ja) * 2003-06-09 2010-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング パピローマウイルスのインヒビター

Also Published As

Publication number Publication date
CA2652469A1 (fr) 2007-11-29
CA2652469C (fr) 2016-05-03
US9974779B2 (en) 2018-05-22
JP2009537595A (ja) 2009-10-29
ES2436772T3 (es) 2014-01-07
AR061027A1 (es) 2008-07-30
EP2024350B1 (fr) 2013-09-18
FR2901273A1 (fr) 2007-11-23
BRPI0711208A2 (pt) 2011-03-22
MX2008014771A (es) 2008-11-28
DK2024350T3 (da) 2013-12-09
WO2007135106A1 (fr) 2007-11-29
PT2024350E (pt) 2013-12-11
US20120220633A1 (en) 2012-08-30
CN101466693B (zh) 2012-12-12
EP2024350A1 (fr) 2009-02-18
US9452991B2 (en) 2016-09-27
US20180021318A9 (en) 2018-01-25
US20090209586A1 (en) 2009-08-20
CN101466693A (zh) 2009-06-24
JP5399237B2 (ja) 2014-01-29
US20170079968A1 (en) 2017-03-23
US8207373B2 (en) 2012-06-26

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