FR2872912B1 - Nouveau systeme microfluidique et procede de capture de cellules - Google Patents

Nouveau systeme microfluidique et procede de capture de cellules

Info

Publication number
FR2872912B1
FR2872912B1 FR0407722A FR0407722A FR2872912B1 FR 2872912 B1 FR2872912 B1 FR 2872912B1 FR 0407722 A FR0407722 A FR 0407722A FR 0407722 A FR0407722 A FR 0407722A FR 2872912 B1 FR2872912 B1 FR 2872912B1
Authority
FR
France
Prior art keywords
microfluidic system
capturing cells
new microfluidic
new
capturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0407722A
Other languages
English (en)
Other versions
FR2872912A1 (fr
Inventor
Bernard Bennetau
Phuong Lan Tran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phuong Lan Tran Fr
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite des Sciences et Tech (Bordeaux 1)
Ecole Normale Superieure de Cachan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Universite des Sciences et Tech (Bordeaux 1), Ecole Normale Superieure de Cachan filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR0407722A priority Critical patent/FR2872912B1/fr
Priority to US11/571,808 priority patent/US20080318203A1/en
Priority to PCT/FR2005/001753 priority patent/WO2006016044A1/fr
Priority to EP05788488A priority patent/EP1766404A1/fr
Priority to JP2007519842A priority patent/JP2008505630A/ja
Priority to CA002573044A priority patent/CA2573044A1/fr
Publication of FR2872912A1 publication Critical patent/FR2872912A1/fr
Application granted granted Critical
Publication of FR2872912B1 publication Critical patent/FR2872912B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877Flow chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099Characterised by type of test elements
    • G01N2035/00158Elements containing microarrays, i.e. "biochip"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1034Transferring microquantities of liquid
FR0407722A 2004-07-09 2004-07-09 Nouveau systeme microfluidique et procede de capture de cellules Expired - Fee Related FR2872912B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR0407722A FR2872912B1 (fr) 2004-07-09 2004-07-09 Nouveau systeme microfluidique et procede de capture de cellules
US11/571,808 US20080318203A1 (en) 2004-07-09 2005-07-07 Novel Microfluidic System and Method for Capturing Cells
PCT/FR2005/001753 WO2006016044A1 (fr) 2004-07-09 2005-07-07 Nouveau systeme microfluidique et procede de capture de cellules.
EP05788488A EP1766404A1 (fr) 2004-07-09 2005-07-07 Nouveau systeme microfluidique et procede de capture de cellules.
JP2007519842A JP2008505630A (ja) 2004-07-09 2005-07-07 新規のマイクロ流体システム及び細胞捕獲方法
CA002573044A CA2573044A1 (fr) 2004-07-09 2005-07-07 Nouveau systeme microfluidique et procede de capture de cellules

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0407722A FR2872912B1 (fr) 2004-07-09 2004-07-09 Nouveau systeme microfluidique et procede de capture de cellules

Publications (2)

Publication Number Publication Date
FR2872912A1 FR2872912A1 (fr) 2006-01-13
FR2872912B1 true FR2872912B1 (fr) 2007-03-02

Family

ID=34947437

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0407722A Expired - Fee Related FR2872912B1 (fr) 2004-07-09 2004-07-09 Nouveau systeme microfluidique et procede de capture de cellules

Country Status (6)

Country Link
US (1) US20080318203A1 (fr)
EP (1) EP1766404A1 (fr)
JP (1) JP2008505630A (fr)
CA (1) CA2573044A1 (fr)
FR (1) FR2872912B1 (fr)
WO (1) WO2006016044A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4984648B2 (ja) * 2006-05-26 2012-07-25 富士通株式会社 検出素子、その製造方法、および標的検出装置
JP4850855B2 (ja) * 2007-03-22 2012-01-11 信越化学工業株式会社 マイクロアレイ作製用基板の製造方法
US9422409B2 (en) 2008-10-10 2016-08-23 Massachusetts Institute Of Technology Method of hydrolytically stable bonding of elastomers to substrates
FR2941531B1 (fr) 2009-01-26 2019-07-05 Phuong Lan TRAN Dispositif microfluidique, systeme et procede de mise en oeuvre
WO2010083852A1 (fr) * 2009-01-26 2010-07-29 Tethis S.R.L. Dispositif microfluidique fonctionnalisé pour immunofluorescence
WO2011063416A2 (fr) * 2009-11-23 2011-05-26 The General Hospital Corporation Dispositifs microfluidiques destinés à capturer des composants d'un échantillon biologique
GB201003886D0 (en) * 2010-03-09 2010-04-21 Univ Leeds Biosensor apparatus and use thereof
WO2012120266A1 (fr) * 2011-03-10 2012-09-13 University Of Leeds Appareil capteur et utilisation de celui-ci
EP2694965B1 (fr) * 2011-04-05 2017-01-18 Purdue Research Foundation Système micro-fluidique utilisant des micro-ouvertures pour une détection de haut débit de unitees
US20130330711A1 (en) * 2012-06-06 2013-12-12 National Taiwan University Sensor for detection of a target of interest
US9889445B2 (en) 2013-10-22 2018-02-13 Berkeley Lights, Inc. Micro-fluidic devices for assaying biological activity
CN109142717B (zh) * 2013-10-22 2021-11-16 伯克利之光生命科技公司 用于测定生物活性的微流体装置
CN103937658B (zh) * 2014-03-28 2015-11-04 武汉介观生物科技有限责任公司 一种稀有细胞检测芯片及其应用
US10723988B2 (en) 2015-04-22 2020-07-28 Berkeley Lights, Inc. Microfluidic cell culture
US10799865B2 (en) 2015-10-27 2020-10-13 Berkeley Lights, Inc. Microfluidic apparatus having an optimized electrowetting surface and related systems and methods
CN109689213B (zh) 2016-05-26 2022-10-14 伯克利之光生命科技公司 共价修饰的表面、试剂盒及制备方法和用途
EP3490696B1 (fr) * 2016-07-28 2023-09-06 Captec Medical KFT. Dispositif de capture d'écoulement pour l'élimination de cellules du sang
CN107338184A (zh) * 2017-08-02 2017-11-10 苏州博福生物医药科技有限公司 一种用于捕获细胞或溶液中生物分子的捕获筛及装置
EP3444034A1 (fr) * 2017-08-18 2019-02-20 XanTec bioanalytics GmbH Cellule d'écoulement pour enrichissement sélectif de particules ou de cellules cibles
JP2021520847A (ja) * 2018-04-07 2021-08-26 ルマサイト リミティド ライアビリティ カンパニー 流体オートサンプラ及び培養器
CN113000079B (zh) * 2020-06-02 2023-09-22 山东大学 一种重金属离子检测电化学微流控传感芯片及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002541458A (ja) * 1999-04-01 2002-12-03 セロミックス インコーポレイテッド 細胞ベースのスクリーニングのための小型化細胞アレイ製法および装置
FR2804116B1 (fr) * 2000-01-20 2002-08-23 Centre Nat Rech Scient Composes organosilicies, leur procede de preparation et leurs utilisations
FR2804129B1 (fr) * 2000-01-20 2002-10-18 Centre Nat Rech Scient Procedes de synthese et d'immobilisation d'acides nucleiques sur un support solide silanise
EP1184349A1 (fr) * 2000-09-01 2002-03-06 A.S.B.L. Facultes Universitaires Notre-Dame De La Paix Méthode d'obtention d'une activation de surface d'un support solide pour la formation de microarrangements biopuces
EP2359689B1 (fr) * 2002-09-27 2015-08-26 The General Hospital Corporation Dispositif microfluidique pour la séparation de cellules et usage du dispositif

Also Published As

Publication number Publication date
JP2008505630A (ja) 2008-02-28
EP1766404A1 (fr) 2007-03-28
WO2006016044B1 (fr) 2006-04-06
WO2006016044A1 (fr) 2006-02-16
US20080318203A1 (en) 2008-12-25
CA2573044A1 (fr) 2006-02-16
FR2872912A1 (fr) 2006-01-13

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