SG11201809539RA - Covalently modified surfaces, kits, and methods of preparation and use - Google Patents

Covalently modified surfaces, kits, and methods of preparation and use

Info

Publication number
SG11201809539RA
SG11201809539RA SG11201809539RA SG11201809539RA SG11201809539RA SG 11201809539R A SG11201809539R A SG 11201809539RA SG 11201809539R A SG11201809539R A SG 11201809539RA SG 11201809539R A SG11201809539R A SG 11201809539RA SG 11201809539R A SG11201809539R A SG 11201809539RA
Authority
SG
Singapore
Prior art keywords
international
suite
street
emeryville
california
Prior art date
Application number
SG11201809539RA
Inventor
Lowe, Jr
Alexander Mastroianni
Mark White
Gregory Lavieu
Kristin Beaumont
Original Assignee
Berkeley Lights Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berkeley Lights Inc filed Critical Berkeley Lights Inc
Publication of SG11201809539RA publication Critical patent/SG11201809539RA/en

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
    • B81C1/00206—Processes for functionalising a surface, e.g. provide the surface with specific mechanical, chemical or biological properties
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/088—Channel loops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00—Specific applications of microelectromechanical systems
    • B81B2201/05—Microfluidics
    • B81B2201/058—Microfluidics not provided for in B81B2201/051 - B81B2201/054

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1111111111111011010101111101011111111101011111111111111100111011101111 1111111 Organization (10) International Publication Number International Bureau (43) International Publication Date .....0\"\"\" WO 2017/205830 Al 30 November 2017 (30.11.2017) WIPO I PCT (51) International Patent Classification: (72) Inventors; and BOIL 3/00 (2006.01) G01N 33/53 (2006.01) (71) Applicants: LOWE, Randall D. [US/US]; 5858 Hor- C12M 1/00 (2006.01) B81B 7/04 (2006.01) ton Street, Suite 320, Emeryville, California 94608 (US). GO1N 33/50 (2006.01) MASTROIANNI, Alexander J. [US/US]; 5858 Horton (21) International Application Number: Street, Suite 320, Emeryville, California 94608 (US). WHITE, Mark P. [US/US]; 5858 Horton Street, Suite 320, PCT/US2017/034832 Emeryville, California 94608 (US). LAVIEU, Gregory G. (22) International Filing Date: [FR/FR]; 16 Villa Broussais, 94400 Vitry Sur Seine (FR). 26 May 2017 (26.05.2017) BEAUMONT, Kristin G. [US/US]; 354 E. 91st Street, #907, New York, New York 10128 (US). (25) Filing Language: English (74) Agent: MCNEILL, Rebecca M.; MCNEILL BAUR (26) Publication Language: English PLLC, 125 Cambridge Park Drive, Suite 301, Cambridge, (30) Priority Data: Massachusetts 02140 (US). 62/342,131 26 May 2016 (26.05.2016) US (81) Designated States (unless otherwise indicated, for every 62/345,603 03 June 2016 (03.06.2016) US kind of national protection available): AE, AG, AL, AM, 62/353,938 23 June 2016 (23.06.2016) US AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, 62/410,238 19 October 2016 (19.10.2016) US CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, 62/411,191 21 October 2016 (21.10.2016) US DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (71) Applicant: BERKELEY LIGHTS, INC. [US/US]; 5858 HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, Hoon Street, Suite 320, Emeryville, California 94608 KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, -- rt (US). MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, = PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, (54) Title: COVALENTLY MODIFIED SURFACES, KITS, AND METHODS OF PREPARATION AND USE 154 — 17 170 = 56 . Master Um rolle 5r3 Display — I/0 CM Memory Device = = 16' 162 164 166 168 = = Media Module Motive Module Imaging Module Tilting Module Other Modules = = = — I 5Ce = = = L._ 152 100 128 120 130 110 128 ,,, 126 4:::` ...„, 109 102 124 = 132 17 c — — = 180 . — 11 t )----4 Or >.' 08 — 104 114 122 4 02 107 Il 19 Power Source 190 © en FIG. IA ot kin 0 N ---- (57) : In biosciences and related fields, it can be useful to modify surfaces of apparatuses, devices, and materials that contact IN biomaterials such as biomolecules and biological micro-objects. Described herein are surface modifying and surface functionalizing ,- 1 0 reagents, preparation thereof, and methods for modifying surfaces to provide improved or altered performance with biomaterials. N C [Continued on next page] WO 2017/205830 Al MIDEDIMOMOIDEIROIDEM00101011ififiMMOVOIMIE SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))
SG11201809539RA 2016-05-26 2017-05-26 Covalently modified surfaces, kits, and methods of preparation and use SG11201809539RA (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662342131P 2016-05-26 2016-05-26
US201662345603P 2016-06-03 2016-06-03
US201662353938P 2016-06-23 2016-06-23
US201662410238P 2016-10-19 2016-10-19
US201662411191P 2016-10-21 2016-10-21
PCT/US2017/034832 WO2017205830A1 (en) 2016-05-26 2017-05-26 Covalently modified surfaces, kits, and methods of preparation and use

Publications (1)

Publication Number Publication Date
SG11201809539RA true SG11201809539RA (en) 2018-12-28

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SG10202008265XA SG10202008265XA (en) 2016-05-26 2017-05-26 Covalently modified surfaces, kits, and methods of preparation and use
SG11201809539RA SG11201809539RA (en) 2016-05-26 2017-05-26 Covalently modified surfaces, kits, and methods of preparation and use

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Country Status (10)

Country Link
US (2) US11007520B2 (en)
EP (1) EP3463665B1 (en)
JP (2) JP7046415B2 (en)
KR (1) KR20190010641A (en)
CN (2) CN109689213B (en)
AU (2) AU2017271673B2 (en)
CA (1) CA3022623A1 (en)
IL (1) IL263274B2 (en)
SG (2) SG10202008265XA (en)
WO (1) WO2017205830A1 (en)

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