FR2833610B1 - Construits cellulaires cultives in vitro, preparation et utilisations - Google Patents

Construits cellulaires cultives in vitro, preparation et utilisations

Info

Publication number
FR2833610B1
FR2833610B1 FR0116265A FR0116265A FR2833610B1 FR 2833610 B1 FR2833610 B1 FR 2833610B1 FR 0116265 A FR0116265 A FR 0116265A FR 0116265 A FR0116265 A FR 0116265A FR 2833610 B1 FR2833610 B1 FR 2833610B1
Authority
FR
France
Prior art keywords
cultive
vitro
preparation
cell constructs
constructs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0116265A
Other languages
English (en)
Other versions
FR2833610A1 (fr
Inventor
Annie Black
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NATURAL IMPLANT
Original Assignee
NATURAL IMPLANT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0116265A priority Critical patent/FR2833610B1/fr
Application filed by NATURAL IMPLANT filed Critical NATURAL IMPLANT
Priority to AU2002364653A priority patent/AU2002364653B2/en
Priority to US10/498,264 priority patent/US20050053585A1/en
Priority to IL16234302A priority patent/IL162343A0/xx
Priority to BR0214860-9A priority patent/BR0214860A/pt
Priority to PCT/FR2002/004360 priority patent/WO2003052084A2/fr
Priority to EP02804924A priority patent/EP1453955A2/fr
Priority to CNA028250338A priority patent/CN1604962A/zh
Priority to PL02370703A priority patent/PL370703A1/xx
Priority to CA002469611A priority patent/CA2469611A1/fr
Publication of FR2833610A1 publication Critical patent/FR2833610A1/fr
Application granted granted Critical
Publication of FR2833610B1 publication Critical patent/FR2833610B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/386—Ligaments, tendons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3865—Dental/periodontal tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/066—Tenocytes; Tendons, Ligaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/42—Organic phosphate, e.g. beta glycerophosphate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/10—Mineral substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/10—Mineral substrates
    • C12N2533/18—Calcium salts, e.g. apatite, Mineral components from bones, teeth, shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Microbiology (AREA)
  • Rehabilitation Therapy (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR0116265A 2001-12-14 2001-12-14 Construits cellulaires cultives in vitro, preparation et utilisations Expired - Fee Related FR2833610B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR0116265A FR2833610B1 (fr) 2001-12-14 2001-12-14 Construits cellulaires cultives in vitro, preparation et utilisations
PL02370703A PL370703A1 (en) 2001-12-14 2002-12-13 Cell constructs cultured in vitro, preparation and uses
IL16234302A IL162343A0 (en) 2001-12-14 2002-12-13 Cell constructs cultured in vitro, preparation anduses
BR0214860-9A BR0214860A (pt) 2001-12-14 2002-12-13 Construto ou tecido celular, processo de preparação de um construto celular, utilização de um construto, método de preparação de um implante com ajuda de um construto, kit para a preparação de um construto, composição farmacêutica e implante
PCT/FR2002/004360 WO2003052084A2 (fr) 2001-12-14 2002-12-13 Construits cellulaires cultives in vitro, preparation et utilisations
EP02804924A EP1453955A2 (fr) 2001-12-14 2002-12-13 Construits cellulaires cultives in vitro, preparation et utilisations
AU2002364653A AU2002364653B2 (en) 2001-12-14 2002-12-13 Cell constructs cultured in vitro, preparation and uses
US10/498,264 US20050053585A1 (en) 2001-12-14 2002-12-13 Cell constructs cultured in vitro, preparation and uses
CA002469611A CA2469611A1 (fr) 2001-12-14 2002-12-13 Construits cellulaires cultives in vitro, preparation et utilisations
CNA028250338A CN1604962A (zh) 2001-12-14 2002-12-13 体外培养的细胞构建物、制备及应用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0116265A FR2833610B1 (fr) 2001-12-14 2001-12-14 Construits cellulaires cultives in vitro, preparation et utilisations

Publications (2)

Publication Number Publication Date
FR2833610A1 FR2833610A1 (fr) 2003-06-20
FR2833610B1 true FR2833610B1 (fr) 2007-01-26

Family

ID=8870550

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0116265A Expired - Fee Related FR2833610B1 (fr) 2001-12-14 2001-12-14 Construits cellulaires cultives in vitro, preparation et utilisations

Country Status (10)

Country Link
US (1) US20050053585A1 (fr)
EP (1) EP1453955A2 (fr)
CN (1) CN1604962A (fr)
AU (1) AU2002364653B2 (fr)
BR (1) BR0214860A (fr)
CA (1) CA2469611A1 (fr)
FR (1) FR2833610B1 (fr)
IL (1) IL162343A0 (fr)
PL (1) PL370703A1 (fr)
WO (1) WO2003052084A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7052907B2 (en) * 2000-07-21 2006-05-30 The United States Of America As Represented By The Department Of Health And Human Services Adult human dental pulp stem cells in vitro and in vivo
US9587222B2 (en) * 2003-08-01 2017-03-07 Cellseed Inc. Three-dimensional tissue structure
JP4827729B2 (ja) * 2004-04-25 2011-11-30 株式会社セルシード 培養歯根膜細胞シート、製造方法及びその利用方法
CN101316926A (zh) * 2005-09-30 2008-12-03 复制基因股份公司 用于分化干细胞的方法及其在牙病治疗中的用途
RU2498808C9 (ru) 2006-03-03 2014-01-20 Огенодженесис, Инк. Способ лечения состояния ротовой полости больного (варианты)
WO2008097906A2 (fr) 2007-02-02 2008-08-14 The Regents Of The University Of Michigan Système et procédé pour former des constructions d'os, de ligament et de ligament osseux
CN101134946B (zh) * 2007-08-03 2011-12-21 陆洪光 一种黑色素瘤体外模型的制作方法
WO2009020651A2 (fr) * 2007-08-08 2009-02-12 Pervasis Therapeutics, Inc. Matériaux et procédés pour traiter un dommage causé au système squelettique et favoriser une réparation et une régénération du système squelettique
US8932581B2 (en) 2007-11-19 2015-01-13 Ben Gurion University Of The Negev Research And Development Authority Calcium-mediated effects of coral and methods of use thereof
WO2009151678A1 (fr) * 2008-03-11 2009-12-17 Massachusetts Institute Of Technology Surfaces sensibles aux stimuli
DE102008049014A1 (de) * 2008-09-25 2010-04-22 Bagambisa, Frank, Dr. Dentalimplantat zur Implantation in einen menschlichen oder tierischen Kieferknochen und Verfahren zu seiner Herstellung
CN102068318B (zh) * 2010-12-21 2012-11-21 四川大学 生物牙根支架材料的构建方法
CN103611193B (zh) * 2013-11-26 2015-05-27 中山大学 一种碳酸钙微球-细胞外基质复合材料及其制备方法和应用
EP3370791A1 (fr) 2015-11-03 2018-09-12 Ariel-University Research and Development Company Ltd. Compositions destinées à la régénération et à la réparation de tissu nerveux

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891558A (en) * 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
CA2198978A1 (fr) * 1996-03-01 1997-09-01 Clemens Antoni Van Blitterswijk Methode pour la production d'os in vitro
BR9915476A (pt) * 1998-11-19 2002-01-02 Organogenesis Inc Construtos de tecidos feitos por bioengenharia e métodos para a sua produção e utilização
US6287340B1 (en) * 1999-05-14 2001-09-11 Trustees Of Tufts College Bioengineered anterior cruciate ligament
US6233476B1 (en) * 1999-05-18 2001-05-15 Mediguide Ltd. Medical positioning system
US6479064B1 (en) * 1999-12-29 2002-11-12 Children's Medical Center Corporation Culturing different cell populations on a decellularized natural biostructure for organ reconstruction

Also Published As

Publication number Publication date
AU2002364653B2 (en) 2007-10-18
WO2003052084A3 (fr) 2003-12-11
AU2002364653A1 (en) 2003-06-30
IL162343A0 (en) 2005-11-20
CN1604962A (zh) 2005-04-06
PL370703A1 (en) 2005-05-30
EP1453955A2 (fr) 2004-09-08
BR0214860A (pt) 2004-12-14
US20050053585A1 (en) 2005-03-10
FR2833610A1 (fr) 2003-06-20
CA2469611A1 (fr) 2003-06-26
WO2003052084A2 (fr) 2003-06-26

Similar Documents

Publication Publication Date Title
FR14C0064I2 (fr) Anticorps anti-il-6, compositions, methodes et utilisations associees
HUP0302128A3 (en) Anti-dual integrin antibodies, compositions, methods and uses
AU2002225681A1 (en) Yeast-dentritic cell vaccines and uses thereof
PT1419150E (pt) Derivados de 1-fenilsulfonil-1,3-di-hidro-2h-indol-2-ona, sua preparacao e sua aplicacao em terapeutica
EE200200175A (et) Asendatud 2-tio-3,5-ditsüano-4-arüül-6-aminopüridiinid ja nende kasutamine
EE200200613A (et) 3-lämmastik-6,7-dihapniksteroidid ja nende kasutamine
ITPD20020138A1 (it) Composizione di sostanze a base terpenica, metodo di preparazione e metodo di dispersione in ambiente della medesima.
NO20005692D0 (no) Forbedringer i og vedrörende bygningselementer, og fremgangsmåter vedrörende samme
NO20032830D0 (no) Tetrahydropyridinderivater, fremstilling derav og anvendelse som celle-proliferasjonsinhibitorer
IL164627A0 (en) Novel biomaterials, their preparation and use
FR2833610B1 (fr) Construits cellulaires cultives in vitro, preparation et utilisations
AU2001215798A1 (en) Click-to-add, jot-it-down, and add banner
DE60235547D1 (de) En daraus, deren herstellung und verwendung
DE60142405D1 (de) Multi-axiale lastzelle
IL161472A0 (en) In vitro micro-organs, and uses related thereto
FR2828491B1 (fr) Nouvelle membrane supportee, preparation et utilisations
FR2833599B1 (fr) Polysaccharide amphotere, composition et utilisation
GB0229261D0 (en) Cells,culture methods and their uses
NO20025209L (no) Cyklipostiner, deres fremstilling og anvendelse
GB0102717D0 (en) Cells and uses therefor
NO20024107L (no) Tienopyridin derivater, deres fremstilling og anvendelse
GB0119497D0 (en) Expression of modified antibodies in avian cells
AU8229901A (en) Genes and proteins, and their uses
AU2001282290A1 (en) Htert-immortalised cell lines, their preparation and use
FR2802550B1 (fr) Biopuces, preparation et utilisations

Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20090831