BR0214860A - Construto ou tecido celular, processo de preparação de um construto celular, utilização de um construto, método de preparação de um implante com ajuda de um construto, kit para a preparação de um construto, composição farmacêutica e implante - Google Patents

Construto ou tecido celular, processo de preparação de um construto celular, utilização de um construto, método de preparação de um implante com ajuda de um construto, kit para a preparação de um construto, composição farmacêutica e implante

Info

Publication number
BR0214860A
BR0214860A BR0214860-9A BR0214860A BR0214860A BR 0214860 A BR0214860 A BR 0214860A BR 0214860 A BR0214860 A BR 0214860A BR 0214860 A BR0214860 A BR 0214860A
Authority
BR
Brazil
Prior art keywords
construct
preparing
construction
implant
cellular
Prior art date
Application number
BR0214860-9A
Other languages
English (en)
Inventor
Annie Black
Jean-Louis Romette
Original Assignee
Natural Implant
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natural Implant filed Critical Natural Implant
Publication of BR0214860A publication Critical patent/BR0214860A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/386—Ligaments, tendons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3865—Dental/periodontal tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/066—Tenocytes; Tendons, Ligaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/42—Organic phosphate, e.g. beta glycerophosphate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/10—Mineral substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/10—Mineral substrates
    • C12N2533/18—Calcium salts, e.g. apatite, Mineral components from bones, teeth, shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Rehabilitation Therapy (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Urology & Nephrology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"CONSTRUTO OU TECIDO CELULAR, PROCESSO DE PREPARAçãO DE UM CONSTRUTO CELULAR, UTILIZAçãO DE UM CONSTRUTO, MéTODO DE PREPARAçãO DE UM IMPLANTE COM AJUDA DE UM CONSTRUTO, KIT PARA A PREPARAçãO DE UM CONSTRUTO, COMPOSIçãO FARMACêUTICA E IMPLANTE". A presente invenção refere-se a um construto celular cultivado in vitro caracterizada pelo fato de compreender: (i) células animais cultivadas in vitro nas condições que asseguram a formação de uma estrutura tissular tridimensional e (ii) uma matriz extracelular endógena na qual as referidas células são aprisionadas, e pelo fato de compreender, dentre as referidas células, células que têm uma capacidade de mineralização e/ou ossificação. A invenção é particularmente utilizável no domínio dos enxertos ou de implantologia (reconstituição ou reparação tissular), bem como na indústria farmacêutica, para o estudo dos tecidos e análise do perfil tóxico ou benéfico de moléculas susceptíveis capazes de serem usadas no desenvolvimento farmacêutico e/ou nas composições farmacêuticas.
BR0214860-9A 2001-12-14 2002-12-13 Construto ou tecido celular, processo de preparação de um construto celular, utilização de um construto, método de preparação de um implante com ajuda de um construto, kit para a preparação de um construto, composição farmacêutica e implante BR0214860A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0116265A FR2833610B1 (fr) 2001-12-14 2001-12-14 Construits cellulaires cultives in vitro, preparation et utilisations
PCT/FR2002/004360 WO2003052084A2 (fr) 2001-12-14 2002-12-13 Construits cellulaires cultives in vitro, preparation et utilisations

Publications (1)

Publication Number Publication Date
BR0214860A true BR0214860A (pt) 2004-12-14

Family

ID=8870550

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0214860-9A BR0214860A (pt) 2001-12-14 2002-12-13 Construto ou tecido celular, processo de preparação de um construto celular, utilização de um construto, método de preparação de um implante com ajuda de um construto, kit para a preparação de um construto, composição farmacêutica e implante

Country Status (10)

Country Link
US (1) US20050053585A1 (pt)
EP (1) EP1453955A2 (pt)
CN (1) CN1604962A (pt)
AU (1) AU2002364653B2 (pt)
BR (1) BR0214860A (pt)
CA (1) CA2469611A1 (pt)
FR (1) FR2833610B1 (pt)
IL (1) IL162343A0 (pt)
PL (1) PL370703A1 (pt)
WO (1) WO2003052084A2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7707801A (en) * 2000-07-21 2002-02-05 Us Health Adult human dental pulp stem cells in vitro and in vivo
DK2266499T3 (en) * 2003-08-01 2015-06-29 Cellseed Inc Three-dimensional tissue structure.
EP1748064B1 (en) 2004-04-25 2019-04-17 CellSeed Inc. Cultured periodontal ligament cell sheet, process for producing the same and method of use thereof
US20080253999A1 (en) * 2005-09-30 2008-10-16 Kurt Osther Methods For Differentiating Stem Cells and Uses Thereof in the Treatment of Dental Conditions
CN101489395A (zh) * 2006-03-03 2009-07-22 器官发生有限公司 口腔组织再生和修复
US8097455B2 (en) 2007-02-02 2012-01-17 The Regents Of The University Of Michigan System and method for forming skeletal muscle constructs having functional tissue interfaces
CN101134946B (zh) * 2007-08-03 2011-12-21 陆洪光 一种黑色素瘤体外模型的制作方法
EP2535063A1 (en) * 2007-08-08 2012-12-19 Pervasis Therapeutics, Inc. Materials and methods for treating skeletal system damage and promoting skeletal system repair and regeneration
EP2211878B1 (en) * 2007-11-19 2015-04-15 Ben Gurion University of the Negev Research And Development Authority Calcium-mediated effects of coral and methods of use thereof
WO2009151678A1 (en) * 2008-03-11 2009-12-17 Massachusetts Institute Of Technology Stimuli-responsive surfaces
DE102008049014A1 (de) * 2008-09-25 2010-04-22 Bagambisa, Frank, Dr. Dentalimplantat zur Implantation in einen menschlichen oder tierischen Kieferknochen und Verfahren zu seiner Herstellung
CN102068318B (zh) * 2010-12-21 2012-11-21 四川大学 生物牙根支架材料的构建方法
CN103611193B (zh) * 2013-11-26 2015-05-27 中山大学 一种碳酸钙微球-细胞外基质复合材料及其制备方法和应用
WO2017077539A1 (en) 2015-11-03 2017-05-11 Ariel-University Research And Development Company Ltd. Compositions for regeneration and repair of neural tissue

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891558A (en) * 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
DE69733292T2 (de) * 1996-03-01 2006-04-27 Isotis N.V. Verfahren zur in vitro Herstellung von Knochen
CN1333818A (zh) * 1998-11-19 2002-01-30 奥加诺吉尼西斯公司 生物工程化的组织构建物、其制备方法及其应用
US6287340B1 (en) * 1999-05-14 2001-09-11 Trustees Of Tufts College Bioengineered anterior cruciate ligament
US6233476B1 (en) * 1999-05-18 2001-05-15 Mediguide Ltd. Medical positioning system
US6479064B1 (en) * 1999-12-29 2002-11-12 Children's Medical Center Corporation Culturing different cell populations on a decellularized natural biostructure for organ reconstruction

Also Published As

Publication number Publication date
AU2002364653A1 (en) 2003-06-30
US20050053585A1 (en) 2005-03-10
CN1604962A (zh) 2005-04-06
AU2002364653B2 (en) 2007-10-18
WO2003052084A3 (fr) 2003-12-11
FR2833610A1 (fr) 2003-06-20
FR2833610B1 (fr) 2007-01-26
CA2469611A1 (fr) 2003-06-26
IL162343A0 (en) 2005-11-20
EP1453955A2 (fr) 2004-09-08
WO2003052084A2 (fr) 2003-06-26
PL370703A1 (en) 2005-05-30

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011.

B15K Others concerning applications: alteration of classification

Ipc: A61L 27/36 (2006.01), A61L 27/38 (2006.01), C12N 5