FR2754822B1 - Polypeptides comprenant des domaines de la proteine gax, impliques dans la repression de transcription et/ou interagissant avec d'autres proteines, acides nucleiques correspondants et leurs utilisations - Google Patents

Polypeptides comprenant des domaines de la proteine gax, impliques dans la repression de transcription et/ou interagissant avec d'autres proteines, acides nucleiques correspondants et leurs utilisations

Info

Publication number
FR2754822B1
FR2754822B1 FR9612730A FR9612730A FR2754822B1 FR 2754822 B1 FR2754822 B1 FR 2754822B1 FR 9612730 A FR9612730 A FR 9612730A FR 9612730 A FR9612730 A FR 9612730A FR 2754822 B1 FR2754822 B1 FR 2754822B1
Authority
FR
France
Prior art keywords
polypeptides
interacting
proteins
involved
nucleic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9612730A
Other languages
English (en)
Other versions
FR2754822A1 (fr
Inventor
Mahfoudi Abderrahim
Alain Fournier
Christophe Marcireau
Didier Branellec
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Priority to FR9612730A priority Critical patent/FR2754822B1/fr
Priority to US08/950,860 priority patent/US6121005A/en
Priority to EP97911277A priority patent/EP0941243A1/fr
Priority to HU9903956A priority patent/HUP9903956A3/hu
Priority to CZ991318A priority patent/CZ131899A3/cs
Priority to APAP/P/1999/001510A priority patent/AP9901510A0/en
Priority to BR9711947A priority patent/BR9711947A/pt
Priority to CN97199823A priority patent/CN1237980A/zh
Priority to PCT/FR1997/001850 priority patent/WO1998017686A1/fr
Priority to NZ335283A priority patent/NZ335283A/en
Priority to AU48713/97A priority patent/AU741586B2/en
Priority to SK511-99A priority patent/SK51199A3/sk
Priority to EA199900387A priority patent/EA003694B1/ru
Priority to PL97332874A priority patent/PL332874A1/xx
Priority to KR1019990703354A priority patent/KR20000049249A/ko
Priority to CA002268045A priority patent/CA2268045A1/fr
Priority to IL12947897A priority patent/IL129478A0/xx
Priority to JP51902498A priority patent/JP2001503615A/ja
Priority to ZA9709390A priority patent/ZA979390B/xx
Publication of FR2754822A1 publication Critical patent/FR2754822A1/fr
Application granted granted Critical
Publication of FR2754822B1 publication Critical patent/FR2754822B1/fr
Priority to OA9900083A priority patent/OA11034A/fr
Priority to NO991830A priority patent/NO991830L/no
Priority to BG103342A priority patent/BG63548B1/bg
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y10S977/797—Lipid particle
    • Y10S977/798—Lipid particle having internalized material
    • Y10S977/799—Containing biological material
    • Y10S977/80—Nucleic acid, e.g. DNA or RNA
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FR9612730A 1996-10-18 1996-10-18 Polypeptides comprenant des domaines de la proteine gax, impliques dans la repression de transcription et/ou interagissant avec d'autres proteines, acides nucleiques correspondants et leurs utilisations Expired - Fee Related FR2754822B1 (fr)

Priority Applications (22)

Application Number Priority Date Filing Date Title
FR9612730A FR2754822B1 (fr) 1996-10-18 1996-10-18 Polypeptides comprenant des domaines de la proteine gax, impliques dans la repression de transcription et/ou interagissant avec d'autres proteines, acides nucleiques correspondants et leurs utilisations
US08/950,860 US6121005A (en) 1996-10-18 1997-10-15 Polypeptides comprising domains of the GAX protein implicated in the repression of transcription and/or interaction with other proteins, corresponding nucleic acids, and their use
CA002268045A CA2268045A1 (fr) 1996-10-18 1997-10-16 Polypeptides comprenant des domaines de la proteine gax, impliques dans la repression de transcription et/ou interagissant avec d'autres proteines, acides nucleiques correspondants et leurs utilisations
CZ991318A CZ131899A3 (cs) 1996-10-18 1997-10-16 Polypeptidy obsahující domény proteinu GAX, které se účastní represe transkripce, odpovídající nukleové kyseliny a jejich použití
APAP/P/1999/001510A AP9901510A0 (en) 1996-10-18 1997-10-16 Polypeptides comprising gax protein domains, involved in repressing transcription and or interacting with other proteins corresponding nucleic acids andtheir use.
BR9711947A BR9711947A (pt) 1996-10-18 1997-10-16 Polipept¡deo cido nucl-ico cassete e vetor de expressÆo utiliza-{es da prote¡na gax ou de um polipept¡deo de composto que inibem a at¡vidade da prote¡na ki e ou de pcna e para a forma-Æo de um complexo bi-ou tri-partite com as prote¡nas ki e/ou pcna composi-Æo farmac-utica e processo para a sele-Æo e/ou a identifica-Æo de polipept¡deos que interagem com a prote¡na gax ou um dom¡nio de gax
CN97199823A CN1237980A (zh) 1996-10-18 1997-10-16 含有gax蛋白中涉及转录抑制和/或与其他蛋白相作用功能域的多肽,相应的核酸及其应用
PCT/FR1997/001850 WO1998017686A1 (fr) 1996-10-18 1997-10-16 Polypeptides comprenant des domaines de la proteine gax, impliques dans la repression de transcription et/ou interagissant avec d'autres proteines, acides nucleiques correspondants et leurs utilisations
NZ335283A NZ335283A (en) 1996-10-18 1997-10-16 Polypeptides comprising GAX protein domains, involved in repressing transcription and/or interacting with other proteins, corresponding nucleic acids and their use
AU48713/97A AU741586B2 (en) 1996-10-18 1997-10-16 Polypeptides comprising gax protein domains, involved in repressing transcription and/or interacting with other proteins, corresponding nucleic acids and their use
SK511-99A SK51199A3 (en) 1996-10-18 1997-10-16 Polypeptides comprising gax protein domains, involved in repressing transcription and/or interacting with other proteins, corresponding nucleic acids and their use
EA199900387A EA003694B1 (ru) 1996-10-18 1997-10-16 Полипептиды, содержащие домены протеина gax, участвующие в подавлении транскрипции и/или взаимодействующие с другими протеинами, соответствующие нуклеиновые кислоты и их применение
EP97911277A EP0941243A1 (fr) 1996-10-18 1997-10-16 Polypeptides comprenant des domaines de la proteine gax, impliques dans la repression de transcription et/ou interagissant avec d'autres proteines, acides nucleiques correspondants et leurs utilisations
KR1019990703354A KR20000049249A (ko) 1996-10-18 1997-10-16 전사 억제 및/또는 다른 단백질과의 상호작용에 관여하는지에이엑스 단백질 영역을 포함하는 폴리펩타이드, 상응하는핵산 및 이들의 용도
HU9903956A HUP9903956A3 (en) 1996-10-18 1997-10-16 Polypeptides comprising gax protein domains,involved in repressing transcription and/or interacting with other proteins,corresponding nucleic acids and their use
IL12947897A IL129478A0 (en) 1996-10-18 1997-10-16 Polypeptides comprising gax protein domains involved in repressing transcription and/or interacting with other proteins corresponding nucleic acids and their use
JP51902498A JP2001503615A (ja) 1996-10-18 1997-10-16 Ｇａｘタンパク質の、転写の抑制に関与し、及び／又は他のタンパク質と相互作用する領域からなるポリペプチド、対応する核酸およびそれらの使用
PL97332874A PL332874A1 (en) 1996-10-18 1997-10-16 Polypeptides containing protein gax domains involved in repression of transcription and/or interaction with other proteins, appropriate nucleic acids and their application
ZA9709390A ZA979390B (en) 1996-10-18 1997-10-20 Polypeptides comprising domains of the GAX protein which are involved in the repression of transcription and/or which interact with other proteins, corresponding nucleic acids and their uses.
OA9900083A OA11034A (fr) 1996-10-18 1999-04-16 Polypeptides comprenant des domaines de la protéine gax impliqués dans la repression de transcription et/ou interagissant avec d'aoutres protéines acides nucleiques correspondants et leurs utilisations
NO991830A NO991830L (no) 1996-10-18 1999-04-16 Polypeptider omfattende GAX-protein domener, involvert i represjon av transkripsjon og/eller interagerende med andre proteiner, tilsvarende nukleinsyrer og deres anvendelse
BG103342A BG63548B1 (bg) 1996-10-18 1999-04-16 Полипептиди, съдържащи протеинови домени на gax, включени в транскрипцията и/или взаимнодействащи сдруги протеини, съответни нуклеинови киселини и тяхното използване

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9612730A FR2754822B1 (fr) 1996-10-18 1996-10-18 Polypeptides comprenant des domaines de la proteine gax, impliques dans la repression de transcription et/ou interagissant avec d'autres proteines, acides nucleiques correspondants et leurs utilisations

Publications (2)

Publication Number Publication Date
FR2754822A1 FR2754822A1 (fr) 1998-04-24
FR2754822B1 true FR2754822B1 (fr) 1998-11-27

Family

ID=9496803

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9612730A Expired - Fee Related FR2754822B1 (fr) 1996-10-18 1996-10-18 Polypeptides comprenant des domaines de la proteine gax, impliques dans la repression de transcription et/ou interagissant avec d'autres proteines, acides nucleiques correspondants et leurs utilisations

Country Status (22)

Country Link
US (1) US6121005A (fr)
EP (1) EP0941243A1 (fr)
JP (1) JP2001503615A (fr)
KR (1) KR20000049249A (fr)
CN (1) CN1237980A (fr)
AP (1) AP9901510A0 (fr)
AU (1) AU741586B2 (fr)
BG (1) BG63548B1 (fr)
BR (1) BR9711947A (fr)
CA (1) CA2268045A1 (fr)
CZ (1) CZ131899A3 (fr)
EA (1) EA003694B1 (fr)
FR (1) FR2754822B1 (fr)
HU (1) HUP9903956A3 (fr)
IL (1) IL129478A0 (fr)
NO (1) NO991830L (fr)
NZ (1) NZ335283A (fr)
OA (1) OA11034A (fr)
PL (1) PL332874A1 (fr)
SK (1) SK51199A3 (fr)
WO (1) WO1998017686A1 (fr)
ZA (1) ZA979390B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001289652A1 (en) * 2000-06-28 2002-01-08 Aventis Pharma S.A. Compositions and methods for regulating the cell cycle using a ki gene or polypeptide
US8124598B2 (en) 2006-09-14 2012-02-28 Sharon Sageman 7-keto DHEA for psychiatric use
US20100160274A1 (en) * 2007-09-07 2010-06-24 Sharon Sageman 7-KETO DHEA for Psychiatric Use
US20130059773A1 (en) * 2010-02-24 2013-03-07 Veronique Witko-Sarsat Compounds for the treatment of inflammation and neutropenia

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856121A (en) * 1994-02-24 1999-01-05 Case Western Reserve University Growth arrest homebox gene
US5554181A (en) * 1994-05-04 1996-09-10 Regents Of The University Of Minnesota Stent
GB9422175D0 (en) * 1994-11-03 1994-12-21 Univ Dundee Indentification of the p21 waf1-pcna interaction site and therapeutic applications thereof
FR2732357B1 (fr) * 1995-03-31 1997-04-30 Rhone Poulenc Rorer Sa Vecteurs viraux et utilisation pour le traitement des desordres hyperproliferatifs, notamment de la restenose
FR2740344B1 (fr) * 1995-10-31 1997-11-21 Rhone Poulenc Rorer Sa Application de la proteine gax au traitement de cancers

Also Published As

Publication number Publication date
EA003694B1 (ru) 2003-08-28
WO1998017686A1 (fr) 1998-04-30
BR9711947A (pt) 1999-08-24
BG63548B1 (bg) 2002-04-30
IL129478A0 (en) 2000-02-29
AU741586B2 (en) 2001-12-06
CN1237980A (zh) 1999-12-08
SK51199A3 (en) 2000-04-10
EP0941243A1 (fr) 1999-09-15
ZA979390B (en) 1998-05-12
PL332874A1 (en) 1999-10-25
NO991830L (no) 1999-06-16
JP2001503615A (ja) 2001-03-21
US6121005A (en) 2000-09-19
NZ335283A (en) 2001-02-23
AP9901510A0 (en) 1999-06-30
NO991830D0 (no) 1999-04-16
FR2754822A1 (fr) 1998-04-24
HUP9903956A3 (en) 2002-01-28
EA199900387A1 (ru) 1999-10-28
BG103342A (en) 2000-05-31
CA2268045A1 (fr) 1998-04-30
HUP9903956A2 (hu) 2000-03-28
KR20000049249A (ko) 2000-07-25
AU4871397A (en) 1998-05-15
OA11034A (fr) 2003-03-06
CZ131899A3 (cs) 1999-07-14

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