FR2717803B1 - Dérivés substitués d'hétérocycles azotés et leurs isomères, actifs sur le système nerveux central, procédé d'obtention et compositions pharmaceutiques les contenant. - Google Patents

Dérivés substitués d'hétérocycles azotés et leurs isomères, actifs sur le système nerveux central, procédé d'obtention et compositions pharmaceutiques les contenant.

Info

Publication number
FR2717803B1
FR2717803B1 FR9403562A FR9403562A FR2717803B1 FR 2717803 B1 FR2717803 B1 FR 2717803B1 FR 9403562 A FR9403562 A FR 9403562A FR 9403562 A FR9403562 A FR 9403562A FR 2717803 B1 FR2717803 B1 FR 2717803B1
Authority
FR
France
Prior art keywords
isomers
obtaining
active
pharmaceutical compositions
nervous system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9403562A
Other languages
English (en)
Other versions
FR2717803A1 (fr
Inventor
Ahmad Youssef El
Pierre Yves Fiez-Vandal
Elisabeth Laurent
Philippe Maillet
Roland Ollivier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MERAM LAB
Original Assignee
MERAM LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MERAM LAB filed Critical MERAM LAB
Priority to FR9403562A priority Critical patent/FR2717803B1/fr
Priority to PCT/FR1995/000367 priority patent/WO1995026336A1/fr
Priority to US08/704,755 priority patent/US5846980A/en
Priority to EP95914413A priority patent/EP0751937A1/fr
Priority to AU21420/95A priority patent/AU2142095A/en
Priority to CA002186460A priority patent/CA2186460A1/fr
Publication of FR2717803A1 publication Critical patent/FR2717803A1/fr
Application granted granted Critical
Publication of FR2717803B1 publication Critical patent/FR2717803B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR9403562A 1994-03-25 1994-03-25 Dérivés substitués d'hétérocycles azotés et leurs isomères, actifs sur le système nerveux central, procédé d'obtention et compositions pharmaceutiques les contenant. Expired - Fee Related FR2717803B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9403562A FR2717803B1 (fr) 1994-03-25 1994-03-25 Dérivés substitués d'hétérocycles azotés et leurs isomères, actifs sur le système nerveux central, procédé d'obtention et compositions pharmaceutiques les contenant.
PCT/FR1995/000367 WO1995026336A1 (fr) 1994-03-25 1995-03-24 Derives de n-(benzhydryloxyalkyl)-4-(carboxy/carbamoyl-methyl)-piperidine comme agents antidepressifs
US08/704,755 US5846980A (en) 1994-03-25 1995-03-24 N-(benzhydryloxyalkyl)-4-(carboxy/carbamoyl methyl)-piperidine derivatives as antidepressants
EP95914413A EP0751937A1 (fr) 1994-03-25 1995-03-24 Derives de n-(benzhydryloxyalkyl)-4-(carboxy/carbamoyl-methyl)-piperidine comme agents antidepressifs
AU21420/95A AU2142095A (en) 1994-03-25 1995-03-24 N-(benzhydryloxyalkyl)-4-(carboxy/carbamoyl-methyl)-piperidi ne derivatives as antidepressants
CA002186460A CA2186460A1 (fr) 1994-03-25 1995-03-24 Derives de n-(benzhydryloxyalkyl)-4-(carboxy/carbamoyl-methyl)-piperidine comme agents antidepressifs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9403562A FR2717803B1 (fr) 1994-03-25 1994-03-25 Dérivés substitués d'hétérocycles azotés et leurs isomères, actifs sur le système nerveux central, procédé d'obtention et compositions pharmaceutiques les contenant.

Publications (2)

Publication Number Publication Date
FR2717803A1 FR2717803A1 (fr) 1995-09-29
FR2717803B1 true FR2717803B1 (fr) 1996-06-21

Family

ID=9461453

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9403562A Expired - Fee Related FR2717803B1 (fr) 1994-03-25 1994-03-25 Dérivés substitués d'hétérocycles azotés et leurs isomères, actifs sur le système nerveux central, procédé d'obtention et compositions pharmaceutiques les contenant.

Country Status (6)

Country Link
US (1) US5846980A (fr)
EP (1) EP0751937A1 (fr)
AU (1) AU2142095A (fr)
CA (1) CA2186460A1 (fr)
FR (1) FR2717803B1 (fr)
WO (1) WO1995026336A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20014548A3 (cs) 1999-06-29 2002-04-17 Eli Lilly And Company Příprava substituovaných piperidin-4-onů
FR2815031A1 (fr) * 2000-10-11 2002-04-12 Gilles Fillion Compositions et methodes pour la regulation du systeme nerveux
CA2504742A1 (fr) * 2002-11-27 2004-06-17 University Of North Carolina At Chapel Hill Procede de synthese de composes bis-aryl diamidoxime
KR102037494B1 (ko) * 2017-12-11 2019-10-28 씨제이헬스케어 주식회사 광학활성을 갖는 피페리딘 유도체의 중간체 및 이의 제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4910312A (en) * 1985-11-08 1990-03-20 Warner-Lambert Company Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof
FR2603583B1 (fr) * 1986-09-05 1988-12-09 Andre Buzas Derives de la benzhydryloxyethyl-piperidine, procede d'obtention et compositions pharmaceutiques les contenant
JPH02212472A (ja) * 1989-02-10 1990-08-23 Sankyo Co Ltd ジフエニルメトキシエチルピペリジン誘導体
TW230771B (fr) * 1990-08-09 1994-09-21 Sankyo Co

Also Published As

Publication number Publication date
AU2142095A (en) 1995-10-17
FR2717803A1 (fr) 1995-09-29
US5846980A (en) 1998-12-08
EP0751937A1 (fr) 1997-01-08
WO1995026336A1 (fr) 1995-10-05
CA2186460A1 (fr) 1995-10-05

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Legal Events

Date Code Title Description
TP Transmission of property

Free format text: PUBLIE A TORT DANS LE BOPI 98/03 SUIVANT LA NOTIFICATION DANS LE BOPI 98/07

TP Transmission of property
ST Notification of lapse