FR2710059A1 - Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments. - Google Patents

Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments. Download PDF

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Publication number
FR2710059A1
FR2710059A1 FR9310850A FR9310850A FR2710059A1 FR 2710059 A1 FR2710059 A1 FR 2710059A1 FR 9310850 A FR9310850 A FR 9310850A FR 9310850 A FR9310850 A FR 9310850A FR 2710059 A1 FR2710059 A1 FR 2710059A1
Authority
FR
France
Prior art keywords
formula
group
compound
pharmaceutically acceptable
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR9310850A
Other languages
English (en)
French (fr)
Inventor
Nadler Guy Marguerite M Gerard
Cham Laboratoi Pharmaceutiques
Martin Michel Jean Roger
Atoires Pharmaceutiques
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Laboratoires Pharmaceutiques
Original Assignee
SmithKline Beecham Laboratoires Pharmaceutiques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Laboratoires Pharmaceutiques filed Critical SmithKline Beecham Laboratoires Pharmaceutiques
Priority to FR9310850A priority Critical patent/FR2710059A1/fr
Priority to PCT/EP1994/002959 priority patent/WO1995007884A1/en
Priority to AU76943/94A priority patent/AU7694394A/en
Priority to ZA946989A priority patent/ZA946989B/xx
Priority to TW083108466A priority patent/TW274083B/zh
Publication of FR2710059A1 publication Critical patent/FR2710059A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
    • C07C217/84—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/44—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9310850A 1993-09-13 1993-09-13 Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments. Pending FR2710059A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR9310850A FR2710059A1 (fr) 1993-09-13 1993-09-13 Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments.
PCT/EP1994/002959 WO1995007884A1 (en) 1993-09-13 1994-09-05 Alkanediamine derivatives and their use in the treatment of arrhythmic and ischaemic rhythm disorders
AU76943/94A AU7694394A (en) 1993-09-13 1994-09-05 Alkanediamine derivatives and their use in the treatment of arrhythmic and ischaemic rhythm disorders
ZA946989A ZA946989B (en) 1993-09-13 1994-09-12 Alkanediamine derivatives and their use in the treatment of arrhythmia and ischaemic rhythm disorders
TW083108466A TW274083B (enrdf_load_stackoverflow) 1993-09-13 1994-09-14

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9310850A FR2710059A1 (fr) 1993-09-13 1993-09-13 Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments.

Publications (1)

Publication Number Publication Date
FR2710059A1 true FR2710059A1 (fr) 1995-03-24

Family

ID=9450781

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9310850A Pending FR2710059A1 (fr) 1993-09-13 1993-09-13 Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments.

Country Status (5)

Country Link
AU (1) AU7694394A (enrdf_load_stackoverflow)
FR (1) FR2710059A1 (enrdf_load_stackoverflow)
TW (1) TW274083B (enrdf_load_stackoverflow)
WO (1) WO1995007884A1 (enrdf_load_stackoverflow)
ZA (1) ZA946989B (enrdf_load_stackoverflow)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3061499A (en) * 1998-12-04 2000-06-26 Rimma Iliinichna Ashkinazi Aryl- and heteroarylamides of carboalkoxysulfanilic acids

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0233762A2 (en) * 1986-02-15 1987-08-26 BEECHAM - WUELFING GmbH & Co. KG Use of aromatic diamines for the treatment of angina pectoris, and diamines therefor
WO1988002362A1 (en) * 1986-10-02 1988-04-07 Schering Aktiengesellschaft Aryl-n-aminoalkyl-4-(sulfonamido)benzamides, antiarrhytmic agents and compositions thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0233762A2 (en) * 1986-02-15 1987-08-26 BEECHAM - WUELFING GmbH & Co. KG Use of aromatic diamines for the treatment of angina pectoris, and diamines therefor
WO1988002362A1 (en) * 1986-10-02 1988-04-07 Schering Aktiengesellschaft Aryl-n-aminoalkyl-4-(sulfonamido)benzamides, antiarrhytmic agents and compositions thereof

Also Published As

Publication number Publication date
TW274083B (enrdf_load_stackoverflow) 1996-04-11
ZA946989B (en) 1995-10-11
WO1995007884A1 (en) 1995-03-23
AU7694394A (en) 1995-04-03

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