ZA946989B - Alkanediamine derivatives and their use in the treatment of arrhythmia and ischaemic rhythm disorders - Google Patents

Alkanediamine derivatives and their use in the treatment of arrhythmia and ischaemic rhythm disorders

Info

Publication number
ZA946989B
ZA946989B ZA946989A ZA946989A ZA946989B ZA 946989 B ZA946989 B ZA 946989B ZA 946989 A ZA946989 A ZA 946989A ZA 946989 A ZA946989 A ZA 946989A ZA 946989 B ZA946989 B ZA 946989B
Authority
ZA
South Africa
Prior art keywords
arrhythmia
treatment
rhythm disorders
alkanediamine
ischaemic
Prior art date
Application number
ZA946989A
Other languages
English (en)
Inventor
Guy Marguerite Marie Ge Nadler
Michel Jean Roger Martin
Original Assignee
Smithkline Beecham Lab Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Lab Pharma filed Critical Smithkline Beecham Lab Pharma
Publication of ZA946989B publication Critical patent/ZA946989B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
    • C07C217/84—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/44—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA946989A 1993-09-13 1994-09-12 Alkanediamine derivatives and their use in the treatment of arrhythmia and ischaemic rhythm disorders ZA946989B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9310850A FR2710059A1 (fr) 1993-09-13 1993-09-13 Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments.

Publications (1)

Publication Number Publication Date
ZA946989B true ZA946989B (en) 1995-10-11

Family

ID=9450781

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA946989A ZA946989B (en) 1993-09-13 1994-09-12 Alkanediamine derivatives and their use in the treatment of arrhythmia and ischaemic rhythm disorders

Country Status (5)

Country Link
AU (1) AU7694394A (xx)
FR (1) FR2710059A1 (xx)
TW (1) TW274083B (xx)
WO (1) WO1995007884A1 (xx)
ZA (1) ZA946989B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000034234A1 (fr) * 1998-12-04 2000-06-15 Rimma Iliinichna Ashkinazi Aryl- et heteroarylamides d'acides carboalcoxysulfaniliques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751327A (en) * 1985-06-28 1988-06-14 Xerox Corporation Photoconductive imaging members with unsymmetrical squaraine compounds
GB8603765D0 (en) * 1986-02-15 1986-03-19 Beecham Wuelfung Gmbh & Co Kg Compounds

Also Published As

Publication number Publication date
AU7694394A (en) 1995-04-03
WO1995007884A1 (en) 1995-03-23
TW274083B (xx) 1996-04-11
FR2710059A1 (fr) 1995-03-24

Similar Documents

Publication Publication Date Title
HUP0100069A3 (en) 4(3)substituted-4(3)-aminomethyl-pyran, or -thiopyran-piperidine derivatives, their preparation and their use in the treatment of neurological disorders
HUP9800033A3 (en) Compositions for the treatment of dermatological disorders and methods for their use
HUP0004439A3 (en) 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders
EP0730453A4 (en) METHOD FOR THE TREATMENT OF HEART ARRHYTHMIA
IL114586A (en) Droloxifene for use in the treatment of cardiovascular diseases and pharmaceutical compositions comprising same
IL110204A0 (en) Novel indolene derivatives, processes for their preparation and their use for the treatment of cns disorders
EP0892632A4 (en) AGENTS FOR USE IN PHOTOTHERAPEUTIC TREATMENT OF PROLIFERATIVE SKIN DISORDERS
AU7384094A (en) Use of phenethanolamine derivatives in the treatment of gastrointestinal disorders
HU9503441D0 (en) Use of natural products and related synthetic compounds for the treatment of cardiovascular disease
GB9321341D0 (en) Therapeutic compositions for use in the treatment of skin lesions and method of making same
GB2281863B (en) Improvements in relation to medical diathermy
ZA935154B (en) Use of 1,2,5-oxadiazole-2-oxides for the treatment of erectile dysfunctions
NO934311L (no) alfa,omega-diarylalkanderivater, deres fremstilling og anvendelse ved behandling av sirkulasjonssykdommer og psykoser
ZA929390B (en) The use of D-fenfluramine and fenfluramine compounds in the treatment of hypertension in insulin-resistant subjects.
ZA946989B (en) Alkanediamine derivatives and their use in the treatment of arrhythmia and ischaemic rhythm disorders
EP0453658A3 (en) Use of substituted anilides and sulfonamides in the treatment of cardiovascular diseases
SG47098A1 (en) Diamines in the treatment of arrhythmia
GB2275191B (en) Use of antifungal compounds in the treatment of skin disorders
AU4096789A (en) The use of lactam derivatives in the treatment of cognitive disorders
AU7399394A (en) Measuring bioimpedance values and treating mental disorders
EP0893123A4 (en) MEANS OF PREVENTIVE AND CURATIVE TREATMENT OF CONDITIONS RELATED TO DIFFERENT FORMS OF AGING OF THE ORGANISM
GB2279567B (en) Compositions for the treatment of inflammatory proliferative skin disease and their use
AU7755591A (en) The use of synthetic metalloporphyrins in the treatment of hypertension and other vascular disorders
AU2153092A (en) Spirofurane derivatives and their use in the treatment of neurological disorders
EP0456204A3 (en) Use of benzocycloheptathiophenecarboxylic acid derivatives in the treatment of eosinophile accumulation/activation and connected diseases