FR2684295A1 - NUTRIENT COMPOSITION FOR CAPILLARY USE AND PROCESS FOR PREPARING THE SAME. - Google Patents
NUTRIENT COMPOSITION FOR CAPILLARY USE AND PROCESS FOR PREPARING THE SAME. Download PDFInfo
- Publication number
- FR2684295A1 FR2684295A1 FR9201361A FR9201361A FR2684295A1 FR 2684295 A1 FR2684295 A1 FR 2684295A1 FR 9201361 A FR9201361 A FR 9201361A FR 9201361 A FR9201361 A FR 9201361A FR 2684295 A1 FR2684295 A1 FR 2684295A1
- Authority
- FR
- France
- Prior art keywords
- hair
- hydrochloric acid
- sodium
- enzymes
- borax
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 238000004519 manufacturing process Methods 0.000 title claims description 12
- 235000015097 nutrients Nutrition 0.000 title claims 11
- 210000004209 hair Anatomy 0.000 claims abstract description 47
- 102000004190 Enzymes Human genes 0.000 claims abstract description 29
- 108090000790 Enzymes Proteins 0.000 claims abstract description 29
- 239000000758 substrate Substances 0.000 claims abstract description 26
- 238000000855 fermentation Methods 0.000 claims abstract description 20
- 230000004151 fermentation Effects 0.000 claims abstract description 20
- 108010082495 Dietary Plant Proteins Proteins 0.000 claims abstract description 15
- 150000002632 lipids Chemical class 0.000 claims abstract description 14
- 230000000050 nutritive effect Effects 0.000 claims abstract description 14
- 238000001914 filtration Methods 0.000 claims abstract description 4
- 230000001737 promoting effect Effects 0.000 claims abstract description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 33
- 102000004882 Lipase Human genes 0.000 claims description 25
- 108090001060 Lipase Proteins 0.000 claims description 25
- 239000004367 Lipase Substances 0.000 claims description 24
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 24
- 235000019421 lipase Nutrition 0.000 claims description 24
- 240000007594 Oryza sativa Species 0.000 claims description 17
- 235000007164 Oryza sativa Nutrition 0.000 claims description 17
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- 235000019833 protease Nutrition 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 15
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- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims description 14
- 239000002253 acid Substances 0.000 claims description 12
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- 229910000162 sodium phosphate Inorganic materials 0.000 claims description 3
- LSDQPPYUSHWIQQ-UHFFFAOYSA-M sodium;2-(dimethylamino)acetate;hydrochloride Chemical compound [Na+].Cl.CN(C)CC([O-])=O LSDQPPYUSHWIQQ-UHFFFAOYSA-M 0.000 claims description 3
- CIJQGPVMMRXSQW-UHFFFAOYSA-M sodium;2-aminoacetic acid;hydroxide Chemical compound O.[Na+].NCC([O-])=O CIJQGPVMMRXSQW-UHFFFAOYSA-M 0.000 claims description 3
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- SDCJMBBHNJPYGW-UHFFFAOYSA-L disodium;hydrogen carbonate;chloride Chemical compound [Na+].[Na+].Cl.[O-]C([O-])=O SDCJMBBHNJPYGW-UHFFFAOYSA-L 0.000 claims description 2
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- QXADHXQCAQTNGW-UHFFFAOYSA-M sodium;boric acid;hydroxide Chemical compound [OH-].[Na+].OB(O)O QXADHXQCAQTNGW-UHFFFAOYSA-M 0.000 claims 3
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- 108020004707 nucleic acids Proteins 0.000 claims 2
- 230000004936 stimulating effect Effects 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 1
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- 239000004247 glycine and its sodium salt Substances 0.000 claims 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
La composition nutritive à usage capillaire selon l'invention est un produit de fermentation par une enzyme appliquée sur un substrat contenant protéine végétale et lipide végétal. La composition nutritive à usage capillaire, obtenue par filtration des produits fermentés, est sans danger car elle n'est composée que de substances inoffensives et présente d'excellents résultats dans la prévention de la chute des cheveux ainsi que pour favoriser la croissance et la repousse des cheveux.The nutritive composition for hair use according to the invention is a product of fermentation by an enzyme applied to a substrate containing vegetable protein and vegetable lipid. The nutritive composition for hair use, obtained by filtration of fermented products, is safe because it is composed only of harmless substances and has excellent results in preventing hair loss as well as promoting growth and regrowth hair.
Description
COMPOSITION NUTRITIVE A USAGE CAPILLAIRENUTRITIVE COMPOSITION FOR CAPILLARY USE
ET SON PROCEDE DE PREPARATIONAND PROCESS FOR PREPARING THE SAME
La présente invention a pour objet une composition nutritive à usage capillaire et son procédé de préparation Plus particulièrement, l'invention vise une composition nutritive à usage capillaire contenant des produits fermentés obtenus en appliquant, par exemple, un The subject of the present invention is a nutritional composition for capillary use and its method of preparation. More particularly, the invention relates to a nutritional composition for capillary use containing fermented products obtained by applying, for example, a
mélange de lipase et de protéinase ou de la levure de riz sur un substrat contenant une pro- mixture of lipase and proteinase or rice yeast on a substrate containing a
téine végétale, par exemple du son de riz, et un lipide végétal, ainsi que son procédé de préparation. vegetable protein, for example rice bran, and vegetable lipid, as well as its preparation process.
Le véritable mécanisme de la chute et de la pousse des cheveux reste encore à découvrir. The real mechanism of hair loss and growth is yet to be discovered.
Toutefois, on pense en règle générale que les principales causes de la chute des cheveux sont une interruption de la circulation sanguine, un métabolisme trop lent, un excès d'hormones However, it is generally thought that the main causes of hair loss are an interruption of the blood circulation, a slow metabolism, an excess of hormones
mâles, une inflammation de la peau et des allergies. males, inflammation of the skin and allergies.
Un cheveu est composé d'une partie faisant saillie au-dessus de la peau et d'une partie A hair is composed of a part protruding above the skin and a part
située sous la peau Le bulbe pileux situé à la racine du cheveu renferme un tissu appelé cel- under the skin The hair bulb at the root of the hair contains a tissue called
lules papillaires De nombreux vaisseaux capillaires entourent le bulbe pileux et les cel- Papillary lules Many capillary vessels surround the hair bulb and the
lules papillaires sont alimentées par le sang circulant dans les vaisseaux capillaires, assu- papillary blood cells are fed by the blood circulating in the capillaries,
rant le renouvellement de la division cellulaire et la croissance du cheveu. the renewal of cell division and hair growth.
Cependant, si le sang n'alimente pas suffisamment les cellules, l'activité de division cellulaire se ralentit, provoquant l'arrêt de la croissance du cheveu En conséquence, il est souvent reconnu comme indispensable à la croissance des cheveux de stimuler la circulation However, if the blood does not supply the cells enough, the cell division activity slows down, causing the hair to stop growing. As a result, it is often recognized as essential for hair growth to stimulate circulation.
sanguine dans la peau et d'activer les fonctions des cellules. blood in the skin and activate the functions of the cells.
Le follicule capillaire qui entoure le cheveu contient une enzyme appelée 5 a-réductase qui se transforme en 5 -dihydrotestostérone par combinaison avec l'hormone mâle et qui est ensuite transportée via les vaisseaux sanguins jusqu'aux cellules papillaires, ralentissant The hair follicle that surrounds the hair contains an enzyme called 5-reductase that converts to 5-dihydrotestosterone by combination with the male hormone and is then transported via the blood vessels to the papillary cells, slowing down
l'activité de l'adénylcyclase de celles-ci et provoquant le ralentissement de la division cellu- activity of adenylcyclase and causing a slowdown in cell division.
laire Ainsi, le follicule capillaire s'atrophie peu à peu et le cheveu devient duveteux, pour Thus, the hair follicle atrophies little by little and the hair becomes fluffy, for
finir par une calvitie.to finish with baldness.
Comme nous l'avons mentionné plus haut à titre d'exemples, il existe de nombreuses hypothèses sur le mécanisme de la chute et de la pousse des cheveux, hypothèse dont aucune n'a été démontrée Il existe actuellement dans le commerce un très grand nombre de produits As mentioned above as examples, there are many hypotheses about the mechanism of hair loss and growth, a hypothesis of which none has been demonstrated. of products
différents pour la pousse des cheveux, affirmant contenir des substances que les distribu- hair growth, claiming to contain substances that the distributors
teurs pensent efficaces par la compréhension qu'ils ont du mécanisme de stimulation de la circulation sanguine au niveau de la peau de la tête et/ou d'activation des cellules papillaires par exemple Pourtant, une composition capillaire qui soit réellement efficace reste à mettre They think they are effective because of their understanding of the mechanism of stimulation of the blood circulation in the skin of the head and / or of the activation of papillary cells. For example, a hair composition that is really effective remains to be put
sur le marché.on the market.
En pareilles circonstances, l'inventeur de la présente invention a poursuivi une longue In such circumstances, the inventor of the present invention pursued a long
et intense recherche et a finalement abouti à la présente invention d'une composition capil- and intense research and finally resulted in the present invention of a hair
laire nutritive qui produit d'excellents résultats sur les cheveux, et comprenant des pro- nutritive product which produces excellent results on the hair, and
duits fermentés obtenus en appliquant, par exemple, un mélange de lipase et de protéinase ou de la levure de riz sur un substrat contenant une protéine végétale, par exemple du son de fermented products obtained by applying, for example, a mixture of lipase and proteinase or rice yeast on a substrate containing a vegetable protein, for example
riz, et un lipide végétal.rice, and a vegetable lipid.
La présente invention concerne une composition capillaire nutritive comprenant des The present invention relates to a nutritional hair composition comprising
produits fermentés obtenus en appliquant, par exemple, un mélange de lipase et de protéina- fermented products obtained by applying, for example, a mixture of lipase and protein
1 o se ou de la levure de riz sur un substrat contenant une protéine végétale, par exemple du son 1 o se or rice yeast on a substrate containing a vegetable protein, for example bran
de riz, et un lipide végétal, ainsi que son procédé de préparation. of rice, and a vegetable lipid, as well as its method of preparation.
Ledit substrat peut renfermer tout ce qui contient une protéine végétale et un lipide vé- Said substrate may contain anything that contains a vegetable protein and a lipid
gétal L'enzyme pour la fermentation doit posséder la capacité de décomposer la protéine vé- The enzyme for fermentation must have the ability to break down the protein
gétale et le lipide végétal dans le substrat Cette enzyme peut être une lipase et une protéina- This enzyme may be a lipase and a proteinaceous
se On peut également rajouter d'autres types d'enzymes comme l'amylase. It is also possible to add other types of enzymes such as amylase.
Les produits fermentés subissent un processus de filtrage et l'on obtient alors des com- Fermented products undergo a filtering process and
positions capillaires nutritives de la présente invention Celles-ci sont inoffensives pour le corps humain et laissent apparaître d'excellents résultats en empêchant la chute des cheveux Nutritive capillary positions of the present invention These are harmless to the human body and show excellent results in preventing hair loss.
et en favorisant leur croissance et leur repousse. and promoting their growth and regrowth.
La présente invention va maintenant être plus amplement décrite dans la description qui The present invention will now be more fully described in the description which
suit. Le substrat pour la production d'une composition capillaire nutritive selon la présente invention peut être tout ce qui renferme une protéine végétale et un lipide végétal Il peut s'agir, par exemple, de produits tirés de graines tels que le son de riz, la lie de saké, les follows. The substrate for the production of a nutritional hair composition according to the present invention may be all that contains a vegetable protein and a plant lipid. It may be, for example, products derived from seeds such as rice bran, sake, the
germes de blé, le son de fusuma, le millet de sarrasin ou le millet complet (soba), de pro- wheat germ, fusuma bran, buckwheat millet or whole millet (soba),
duits tirés des pois tels que le soja, lie de fromage de soja (okara ou lie de tofu), lait de soja, pois adzuki, farine de soja ou mouture de café, ou encore d'autres produits végétaux tels qu'ignames, taros, mouture de thé, miel, sésame, cacahuètes, graines de lotus, ashitaba, from peas such as soya beans, soy bean dregs (okara or tofu beans), soy milk, adzuki peas, soy flour or coffee grounds, or other plant products such as nuts, taro , tea flour, honey, sesame, peanuts, lotus seeds, ashitaba,
"langues de boeuf', algues wakame ou laminaires Sont toutefois particulièrement avanta- However, beef tongues, wakame or laminar algae are particularly
geux le son de riz, la lie de saké, le son de fusuma, la mouture de café, les germes de blé, le sésame, la lie de fromage de soja (okara ou lie de tofu), le soja et les pois adzuki car ils cheerful rice bran, sake dregs, fusuma bran, coffee grounds, wheat sprouts, sesame, soy cheese dregs (okara or tofu dreg), soybeans and adzuki peas they
contiennent des protéines végétales et des lipides végétaux en quantités bien équilibrées. contain vegetable protein and vegetable lipids in well-balanced amounts.
L'enzyme utilisée pour la fermentation dans la présente invention doit être capable de décomposer à la fois la protéine végétale et le liquide végétal dans ledit substrat Cela peut être une lipase et une protéinase et l'on peut également en ajouter d'autres, comme par exemple l'amylase Outre lipase et protéinase, on peut aussi utiliser la levure de riz qui The enzyme used for the fermentation in the present invention must be able to break down both the vegetable protein and the vegetable liquid in said substrate. This may be a lipase and a proteinase, and others may also be added, such as for example amylase In addition to lipase and proteinase, it is also possible to use rice yeast which
possède la capacité de produire une variété d'enzyme dans un corps vivant. possesses the ability to produce a variety of enzymes in a living body.
La spermato lipase est une des lipases pouvant être mise en oeuvre dans la présente in- Spermato lipase is one of the lipases that can be used in the present invention.
vention, spermato lipase qui est utilisé dans la gamme d'acidité que présentent divers moi- vention, spermato lipase which is used in the range of acidity
sissures, levures, micro-organismes, humeurs (liquides biologiques) ou enzymes extraits d'organes internes On peut plus particulièrement utiliser la lipase du pancréas, du foie, de yeasts, yeasts, micro-organisms, humors (biological fluids) or enzymes extracted from internal organs. Lipase of the pancreas, liver,
la bactérie de la tuberculose, la lipase FIB et la lipase de hima. tuberculosis bacteria, lipase FIB and hima lipase.
La protéinase à utiliser dans la présente invention sera de préférence acide avec le p H le plus approprié On pourra à cet effet utiliser la pepsine, la trypsine ou la chymotrypsine, The proteinase to be used in the present invention will preferably be acidic with the most suitable p H may be used for this purpose pepsin, trypsin or chymotrypsin,
qui ne possèdent aucune base active particulière à l'exception du résidu amino-acide de l'en- which have no particular active base except the amino acid residue of the
zyme proprement dite et ne réclament aucun réactif particulier dans leurs activités enzy- zyme itself and do not require any particular reagents in their enzyme activities.
matiques On pourra encore utiliser la plupart des enzymes ou cathepsines que l'on trouve We can still use most of the enzymes or cathepsins we find
dans les enzymes végétales et les cellules animales, telles par exemple la papaine ou la fici- in plant enzymes and animal cells, such as papain or fici-
ne, qui peuvent être activées par un agent réducteur tel que l'hydrocyanate, l'acide ascor- can be activated by a reducing agent such as hydrocyanate, ascorbic acid or
lu bique, la cystéine ou la glutathione On pourra plus particulièrement utiliser la chymotryp- cysteine or glutathione. In particular, chymotryp-
sine, la trypsine, la pepsine, la carboxy peptidase, la cathepsine A, la cathepsine B, la ca- sine, trypsin, pepsin, carboxy peptidase, cathepsin A, cathepsin B, cat-
thepsine C', la cathepsine 111, la cathepsine IV, I'acylase rénale 1, I'acylase rénale 11, la leu- C, cathepsin III, cathepsin IV, renal acylase 1, renal acylase 11, leukemia,
cine amino peptidase, I'aminotripeptidase, la glycilglycine dipectidase, la prolitase, la pro- amino peptidase, aminotripeptidase, glycilglycine dipectidase, prolitase,
linase, la plasmine, la thrompine, la papaine, la ficine, la protéinase du streptocoque, C 1, la linase, plasmin, thrombin, papain, ficin, streptococcal proteinase, C 1,
peptidase ou la protéinase d'historyticum. peptidase or the historyticum proteinase.
Les produits fermentés peuvent être obtenus par application de l'enzyme sur ledit sub- Fermented products can be obtained by applying the enzyme to said sub-
strat Des analyses par HPLC (chromatographie liquide haute performance) ont été réalisées sur les produits fermentés avec les résultats suivants Lesdites analyses ont été effectuées en utilisant un détecteur (LC-9 A, Shimadzu Seisakusho, Co, Ltd) et des colonnes ( 3 m de HPLC (High Performance Liquid Chromatography) analyzes were performed on the fermented products with the following results. These analyzes were performed using a detector (LC-9A, Shimadzu Seisakusho, Co, Ltd) and columns (3m). of
z O long) L'acétonitrile a été utilisé comme éluant et la température de la colonne a été mainte- long) Acetonitrile was used as the eluent and the temperature of the column was now
nue à 30 C environ, le débit étant d'environ 10 ml/min. naked at about 30 C, the flow rate being about 10 ml / min.
Les produits fermentés contenaient des acides gras tels que acide myristique, acide pal- The fermented products contained fatty acids such as myristic acid, palm acid and
mitique, acide stéarique, acide arachique, acide béhénique, acide lignocérique, acide dodécé- mitic acid, stearic acid, arachic acid, behenic acid, lignoceric acid, dodecene
nique, acide tétradécénique, acide tétradécadiénique, acide pentadécénique, acide hexadécé- tetradecenic acid, tetradecadienic acid, pentadecenic acid, hexadecene
nique, acide oléique, acide linoléique, acide linolénique, acide eicosaénique, acide eicosadié- oleic acid, linoleic acid, linolenic acid, eicosaenic acid, eicosedic acid,
nique, acide arachidonique, acide eicosatriénique, acide docosénique et acide docosahexanique. nicotine, arachidonic acid, eicosatrienic acid, docosenic acid and docosahexanic acid.
Les produits fermentés contenaient aussi des acides aminés tels que leucine, isoleucine, lysi- The fermented products also contained amino acids such as leucine, isoleucine, lysine
ne, méthionine, cystéine, phénylalanine, tyrosine, thréonine, tryptophane, valine, histidi- ne, methionine, cysteine, phenylalanine, tyrosine, threonine, tryptophan, valine, histidine
ne, arginine, acide aspartique, alanine, acide glutamique, glycine, proline et céline. arginine, aspartic acid, alanine, glutamic acid, glycine, proline and ciline.
Il est clair, à partir des résultats des analyses, que les produits fermentés obtenus selon la présente invention contiennent divers acides aminés et acides gras On pense que les acides aminés servent à nourrir les cellules papillaires et que les acides gras servent à activer et à dilater les vaisseaux capillaires, à fournir de l'air humide aux cheveux ce qui leur donne une It is clear from the results of the analyzes that the fermented products obtained according to the present invention contain various amino acids and fatty acids. It is believed that amino acids serve to nourish the papillary cells and that the fatty acids serve to activate and dilate the capillaries, to provide moist air to the hair which gives them a
apparence brillante ainsi qu'à inhiber la 5 a-réductase contenue dans les follicules capil- appearance and to inhibit the 5-a-reductase contained in hair follicles.
laires afin d'empêcher le ramollissement du cheveu On pense également que les composants pris seuls ou en combinaison stimulent la croissance et la repousse des cheveux On notera que les produits fermentés contiennent aussi des acides aminés qui comprennent du soufre ou des acides gras insaturés dont on pense qu'ils possèdent d'excellents effets sur la croissance In order to prevent softening of the hair, it is also believed that the components taken alone or in combination stimulate the growth and regrowth of the hair. It will be appreciated that the fermented products also contain amino acids which include sulfur or unsaturated fatty acids. think they have excellent effects on growth
et la repousse des cheveux.and hair regrowth.
Outre les composants confirmés dans lesdits produits fermentés, les produits obtenus In addition to the confirmed components in said fermented products, the products obtained
par fermentation en appliquant de la levure de riz sur le substrat selon l'invention contien- by fermentation by applying rice yeast to the substrate according to the invention containing
nent en petite quantité de vitamine A, de vitamine BI, de vitamine B 2, de vitamine B 6, de vitamine B 12, de vitamine C, de vitamine E, du cuivre, du fer, du calcium, du phosphore, de small amounts of vitamin A, vitamin BI, vitamin B 2, vitamin B 6, vitamin B 12, vitamin C, vitamin E, copper, iron, calcium, phosphorus,
la purine, de l'acide déoxyribonucléique, de l'acide ribonucléique, de l'adénine, de la guani- purine, deoxyribonucleic acid, ribonucleic acid, adenine, guanidine,
ne, de l'uracile, de la cytosine et de la xanthine, obtenus en utilisant un mélange de lipase et de protéinase, car diverses enzymes, outre la lipase et la protéinase, sont produites dans la ne, uracil, cytosine and xanthine, obtained using a mixture of lipase and proteinase, because various enzymes, besides lipase and proteinase, are produced in the
levure de riz, comme par exemple l'amylase, la glutaminase, la cellulase et la pectinase, dé- yeast, such as amylase, glutaminase, cellulase and pectinase,
composant non seulement les protéines végétales et les lipides végétaux, mais aussi d'autres composants du substrat On pense que ces autres composants stimulent aussi la croissance et not only vegetable proteins and plant lipids, but also other components of the substrate. It is believed that these other components also stimulate growth and
la repousse des cheveux par synergie avec lesdits acides aminés et acides gras. hair regrowth by synergy with said amino acids and fatty acids.
Pour conserver les compositions capillaires nutritives de la présente invention, on peut To preserve the nutritional hair compositions of the present invention, it is possible to
les réfrigérer ou les faire bouillir Toutefois, il n'y a aucun changement fonctionnel ou dé- refrigerate or boil them However, there are no functional or
gradation des effets des compositions capillaires nutritives. gradation of the effects of nutritive hair compositions.
Nous allons donner ci-dessous une description d'un procédé de préparation de la compo- We will give below a description of a process for the preparation of the compound
sition capillaire nutritive de la présente invention Le procédé comprend les étapes consis- Nutritional capillary assembly of the present invention. The process comprises the steps of
tant à appliquer l'enzyme sur un substrat contenant une protéine végétale et un lipide végé- to apply the enzyme to a substrate containing a vegetable protein and a vegetable lipid.
tal et à filtrer les produits fermentés ainsi obtenus. and filter the fermented products thus obtained.
La fermentation est réalisée en milieu aqueux La lipase et la protéinase ou la levure de riz qui produit d'autres enzymes tels que l'amylase sont utilisées comme enzyme La lipase et la protéinase peuvent être appliquées séparément ou appliquées ensemble sous forme de mélange Ledit mélange peut contenir d'autres enzymes comme par exemple l'amylase, de manière à stimuler la fonction de décomposition, et à décomposer d'autres composants dans le substrat Il est avantageux d'appliquer 0,1 % en poids, par rapport au substrat, de chacune The fermentation is carried out in an aqueous medium Lipase and proteinase or rice yeast which produces other enzymes such as amylase are used as an enzyme Lipase and proteinase can be applied separately or applied together in the form of a mixture. Said mixture may contain other enzymes such as amylase, so as to stimulate the decomposition function, and to decompose other components in the substrate It is advantageous to apply 0.1% by weight, relative to the substrate, of each
des enzymes dans ledit mélange Dans le cas de la levure de riz, comme la fonction de décom- enzymes in said mixture In the case of rice yeast, such as the decomposition function
position de ladite levure est faible en comparaison de celle de la lipase ou de la protéinase, il position of said yeast is small in comparison with that of lipase or proteinase, it
vaut mieux ajouter 1 % en poids, par rapport au substrat, de levure de riz. It is better to add 1% by weight, relative to the substrate, of rice yeast.
La température de fermentation sera de préférence la température ambiante, ou com- The fermentation temperature will preferably be room temperature, or
prise en 350 C et 450 C, et on pourra utiliser comme solution tampon, avec un p H compris taken at 350 C and 450 C, and it will be possible to use as a buffer solution, with a p H included
entre 6 et 11, un mélange acide chlorhydrique collidine, ou phosphate de potassium pri- between 6 and 11, a mixture of hydrochloric acid collidine, or potassium phosphate
maire phosphate de potassium secondaire, ou acide chlorhydrique sel sodé du Véronal, ou mayor secondary potassium phosphate, or hydrochloric acid soda salt from Veronal, or
acide chlorhydrique trisaminométhane, ou acide chlorhydrique borax, ou acide borique - hydrochloric acid trisaminomethane, or hydrochloric acid borax, or boric acid -
carbonate de sodium, ou acide chlorhydrique aminoéthyl propane diol, ou chlorure d'am- sodium carbonate, or hydrochloric acid aminoethyl propane diol, or ammonium chloride
monium ammoniaque, ou glycine hydroxyde de sodium, ou acide borique hydroxyde de monium ammonia, or glycine sodium hydroxide, or boric acid hydroxide
sodium, ou acide chlorhydrique diméthylglycinate de sodium, ou bicarbonate de sodium - sodium, or hydrochloric acid dimethylglycinate sodium, or sodium bicarbonate -
carbonate de sodium, ou borax hydroxyde de sodium, ou borax carbonate de sodium, ou acide chlorhydrique carbonate de sodium, ou phosphate de sodium secondaire hydroxyde de sodium, ou autres équivalents Toute combinaison simple ou multiple desdites substances sodium carbonate, or borax sodium hydroxide, or sodium borax carbonate, or hydrochloric acid sodium carbonate, or sodium phosphate secondary sodium hydroxide, or other equivalents Any single or multiple combination of those substances
peut également être utilisée sous forme de mélange. can also be used as a mixture.
Le temps de réaction pour la fermentation sera de préférence compris entre 5 et 10 heures, sous agitation La fin de la réaction peut être connue, pour ce qui est de la lipase, en prenant comme indicateur une couleur prédéterminée, et en vérifiant la quantité d'acides The reaction time for the fermentation will preferably be between 5 and 10 hours, with stirring. The end of the reaction may be known, as far as the lipase is concerned, by taking as indicator a predetermined color, and by checking the quantity of acids
gras extraits qui sont produits par hydrolyse de l'ester, ou encore par dosage électrochi- extracts which are produced by hydrolysis of the ester, or by electrochemical
mique en utilisant une base alcaline Lorsqu'on ne peut mettre en oeuvre facilement ces techniques, on peut utiliser la colorimétrie pour l'alcool extrait lors de l'hydrolyse Pour ce If these techniques can not be easily implemented, colorimetry can be used for the alcohol extracted during the hydrolysis.
qui est de la protéinase, on peut utiliser la colorimétrie à la ninhydrine, qui est la colorimé- which is proteinase, we can use the colorimetry with ninhydrin, which is the colorimetric
trie d'acides aminés par la couleur bleuâtre produite par la ninhydrine lorsqu'elle est sort of amino acids by the bluish color produced by ninhydrin when it is
chauffée Lorsqu'on ne peut mettre en oeuvre facilement cette technique, il est possible d'u- If this technique can not be easily implemented, it is possible to
tiliser le dosage au formol par la méthode de 50 rensen Cette méthode utilise le phénomène de to use the formaldehyde assay by the method of 50 rensen This method uses the phenomenon of
divergence de la courbe de titrage pour le radical a-amino ou imino en présence de formaldé- divergence of the titration curve for the α-amino or imino radical in the presence of formaldehyde
hyde Pour ce qui est de la stérilisation, on préférera la stérilisation en autoclave. As for sterilization, sterilization by autoclave is preferred.
La composition capillaire nutritive de la présente invention est obtenue par adjonction The nutritional hair composition of the present invention is obtained by adding
d'eau ou d'alcool aux produits fermentés après filtration desdits produits fermentés La com- water or alcohol to the fermented products after filtration of said fermented products.
position capillaire nutritive ainsi obtenue peut être utilisée telle quelle ou être mélangée à une lotion capillaire, à une crème capillaire, à un liquide capillaire, à un tonique capillaire, Nutritive capillary position thus obtained can be used as is or be mixed with a hair lotion, a hair cream, a capillary liquid, a hair tonic,
à une pommade, à un shampoing ou à un produit de rinçage. an ointment, shampoo or rinse aid.
Il est possible de mélanger à la composition capillaire nutritive de la présente invention It is possible to mix with the nutritional hair composition of the present invention
certains composants qui sont souvent utilisés dans les traitements capillaires destinés à fa- certain components that are often used in hair treatments intended to
voriser la croissance et la repousse des cheveux, comme par exemple stimulants de la circu- promote hair growth and regrowth, such as stimulants in the circulation.
lation sanguine, stimulants du métabolisme, anti-hormones mâles, antiinflammatoires, anti-allergéniques, produits hydratants, anti- bactériens, ettou produits rafraîchissants Il blood, metabolic stimulants, anti-male hormones, anti-inflammatory, anti-allergenic, moisturizers, antibacterials, and / or refreshing products.
s'agit par exemple de l'acétate de tocophérol, du chlorure de capronium, de dioxyde de carbo- This is, for example, tocopherol acetate, capronium chloride, carbon dioxide,
ne, de l'lnokitiol, du benzoate de pantonyle éthyléther, du pentadécanate de glycéride, de la lnokitiol, ethyl pantheryl benzoate, glyceride pentadecanate,
vitamine H, de l'éthinylestradiol, de l'acide glycylricinoléique, du chlorure de diphénylhy- vitamin H, ethinyl estradiol, glycyl-1-olicoleic acid, diphenyl hy-
drazinium, de l'acide hyaluronique, d'extrait de Minisasanishiki, de mononitroguaiacol, de drazinium, hyaluronic acid, Minisasanishiki extract, mononitroguaiacol,
teinture de Togarashi, de teinture de Shoukyo, de l'hydrocortisone, du chlorure de diphénic- tincture of Togarashi, Shoukyo tincture, hydrocortisone, diphenic
hydrazinium, du D-pantothénylol, de l'acide salicylique, de l'acide lactique, du lactate de so- hydrazinium, D-pantothenylol, salicylic acid, lactic acid, lactate
dium, du menthol, etcdium, menthol, etc.
Exemple 1Example 1
On utilise 500 g de son de riz comme substrat On ajoute 1000 mi d'eau chaude audit son de riz ( 500 g) et l'on mélange soigneusement Le mélange est alors placé dans un récipient 500 g of rice bran is used as the substrate. 1000 ml of hot water is added to the rice bran (500 g) and the mixture is carefully mixed. The mixture is then placed in a container.
adéquat, comme par exemple un récipient en verre ou en plastique, et l'on ajoute 5 g de le- such as a glass or plastic container, and 5 g of
vure de riz audit mélange On ajoute également 3 g de bicarbonate de sodium comme tampon pour contrôler le p H Le récipient est chauffé à une température d'environ 450 C que l'on 3 g of sodium bicarbonate are also added as a buffer to control the pH. The container is heated to a temperature of about 450.degree.
garde constante Le mélange est laissé ainsi une journée entière sous agitation occasionnelle. constant keeping The mixture is left thus a whole day with occasional stirring.
Le mélange devient pâteux et ce liquide pâteux est filtré avec un filtre en toile pour obtenir The mixture becomes pasty and this pasty liquid is filtered with a cloth filter to obtain
environ 1000 ml d'un liquide capillaire nutritif semi-transparent. about 1000 ml of a semitransparent nutritive liquid liquid.
Exemple 2Example 2
On utilise 200 g de mouture de graines de soja comme substrat On ajoute 600 ml d'eau à ladite mouture de graines de soja ( 200 g) On prépare 100 g d'organes internes d'animaux et l'on ajoute 200 ml d'eau auxdits organes internes d'animaux, et l'on broie alors le tout avec un homogénéisateur en verre afin d'obtenir un homogénéisat Ledit homogénéisat est 200 g of soybean meal are used as the substrate. 600 ml of water are added to said soybean meal (200 g). 100 g of internal organs of animals are prepared and 200 ml of water to said internal organs of animals, and then the whole is ground with a glass homogenizer to obtain a homogenizate Said homogenate is
alors centrifugé à une vitesse de 1 500 tr/min Le fluide surnageant ( 100 mi) est alors ré- then centrifuged at a speed of 1500 rpm. The supernatant fluid (100 ml) is then
cupéré et ajouté au substrat On ajoute également à ce moment là un mélange composé de car- The mixture is then added to the substrate.
bonate de sodium et d'acide borique comme tampon pour ajuster le p H à 10 Le mélange est maintenu à 400 C environ L'activité enzymatique est examinée au moyen d'un colorimètre photo-électrique de Kletto (filtre N O 540) et la fin de cette activité est observée après 8 The mixture is maintained at about 400 ° C. The enzyme activity is examined by means of a Kletto photo-electric colorimeter (filter NO 540) and the end. of this activity is observed after 8
heures environ.hours.
On ajoute 40 mi du mélange carbonate de sodium acide borique ( 0,1 M, p H 10) comme tampon au liquide fermenté ainsi obtenu On ajoute alors la chymotrypsine pour obtenir une 40 ml of boric acid sodium carbonate mixture (0.1 M, p H 10) is added as a buffer to the fermented liquid thus obtained. Chymotrypsin is then added to obtain a
molarité de 0,1 M Le mélange est laissé à environ 400 C La confirmation de la fin de la fer- molarity of 0.1 M The mixture is left at about 400 C The confirmation of the end of the iron
mentation est obtenue en mesurant, avec la méthode de Conway, la quantité d'ammoniac dans is obtained by measuring, with Conway's method, the amount of ammonia
des échantillons de liquide de 0,2 mi chacun prélevés sur ledit mélange Au bout de 10 h en- liquid samples of 0.2 ml each taken from said mixture After 10 hours
viron, la production d'ammoniac cesse et la fermentation est terminée Le liquide fermenté viron, ammonia production ceases and fermentation is over Fermented liquid
est alors filtré et lavé à l'eau Une lotion capillaire nutritive est ainsi obtenue. is then filtered and washed with water A nutritive hair lotion is thus obtained.
Exemple 3 On utilise 200 g de mouture d'Adzuki comme substrat On ajoute 500 mi d'eau à cette mouture et le mélange se fait sous forme d'une suspension Séparément, on fait flotter de la EXAMPLE 3 200 g of Adzuki millet are used as substrate. 500 ml of water are added to this milling and the mixture is in the form of a suspension. Separately, the mixture is floated.
lipase obtenue à partir de mycélium FIB dans de l'eau distillée ( 100 ml), et l'on agite en- lipase obtained from mycelium FIB in distilled water (100 ml), and stirred
suite avec un mélangeur de Knapp-March pendant 2 minutes environ, puis on laisse à tem- followed by a Knapp-March mixer for approximately 2 minutes, then leave
pérature ambiante pendant environ 20 minutes Le liquide surnageant obtenu après centri- at room temperature for about 20 minutes The supernatant fluid obtained after centrifugation
fugation du mélange à 2 000 tr/min pendant 30 minutes est ajouté audit mélange de mouture d'Adzuki et d'eau Un tampon de Britton-Robinson (acide phosphorique, acide acétique, acide fugation of the mixture at 2000 rpm for 30 minutes is added to said mixture of Adzuki milling and water. Britton-Robinson buffer (phosphoric acid, acetic acid, acid
borique, soude caustique) est ajouté pour ajuster le p H à 9 On maintient sous agitation pen- boric acid, caustic soda) is added to adjust the pH to 9.
dant environ 8 heures à 350 C environ Le processus de fermentation est suivi par dosage en utilisant de l'acide chlorhydrique alcoolique à 0, 05 M. About 8 hours at about 350 ° C. The fermentation process is monitored by assay using 0.05 M alcoholic hydrochloric acid.
Séparément, de la papaine du commerce dissoute dans un mélange d'eau et d'acide sulf- Separately, commercial papain dissolved in a mixture of water and sulphuric acid
hydrique est envoyée dans le mélange pendant plusieurs heures On ajoute alors de l'alcool audit mélange pour faire précipiter la papaine On ajoute de l'eau à la papaïne raffinée ( 1 g de papaine, 100 ml d'eau) puis on ajoute également un tampon de Britton-Robinson pour ajuster le p H à 9 avant d'ajouter l'ensemble audit liquide de fermentation renfermant ledit substrat Le liquide de fermentation est laissé à 400 C environ La fin de la fermentation est confirmée par dosage, au moyen d'alcool, d'échantillons de liquide de 0,2 ml chacun prélevés The water is then added to the mixture for several hours. Alcohol is then added to the mixture to precipitate the papain. Water is added to the refined papain (1 g of papain, 100 ml of water). Britton-Robinson buffer to adjust the pH to 9 before adding the assembly to said fermentation liquid containing said substrate. The fermentation liquid is left at about 400 ° C. The end of the fermentation is confirmed by assay, by means of alcohol, liquid samples of 0.2 ml each taken
sur ledit liquide de fermentation La fermentation est achevée au bout de 12 heures environ. on said fermentation liquid The fermentation is completed after about 12 hours.
Le liquide fermenté est filtré et l'on obtient ainsi une lotion capillaire nutritive. The fermented liquid is filtered and thus a nutritive hair lotion is obtained.
Exemple 4Example 4
On utilise comme substrat 100 g de lie de fromage de soja (okara ou lie de tofu) On aj- 100 g of soy cheese lees (okara or tofu binder) are used as substrate.
oute à cette lie 500 mi d'eau et l'on maintient le mélange à environ 500 C Séparément, de la lipase rénale commerciale est dissoute ( 1 %) dans de l'eau distillée Ladite eau distillée contenant ladite lipase rénale ( 5 ml) est ajoutée audit mélange On ajoute également 5 ml d'acide phosphorique ( 0,6 M, p H 7) comme tampon et l'ensemble du mélange est maintenu à to 500 ml of water and the mixture is maintained at about 500 ° C. Separately, commercial renal lipase is dissolved (1%) in distilled water Said distilled water containing said renal lipase (5 ml) 5 ml of phosphoric acid (0.6 M, p H 7) is added as a buffer and the whole mixture is maintained at
400 C environ pendant 10 heures environ, avec agitation occasionnelle La fin de la fermen- 400 C for about 10 hours, with occasional stirring The end of fermentation
tation est confirmée par observation de l'arrêt de la production de dioxyde de carbone en uti- This is confirmed by observing the cessation of carbon dioxide production in use.
lisant un manomètre de Warburg.reading a Warburg manometer.
Séparément, on dissout 10 g de pepsine commerciale (Cuhady, 1/10 000 pepsine so- Separately, 10 g of commercial pepsin (Cuhady, 1/10 000 pepsin so-
luble USP (Pharmacopée américaine" dans 10 mi d'une solution d'éthanol à 20 %, et l'on ajoute le tout audit liquide de fermentation On ajoute également mélange acide chlorhydrique ammonium afin d'ajuster le p H à 7 5 Le liquide est laissé à environ 350 C pendant environ USP (American Pharmacopoeia) in 10 ml of a 20% ethanol solution, and the whole is added to said fermentation liquid. Ammonia hydrochloric acid mixture is also added to adjust the pH to 7. is left at about 350 C for about
heures Il est alors filtré au moyen d'un filtre ( 5 g) Le p H est alors de 7 Le liquide fil- hours It is then filtered by means of a filter (5 g) The p H is then 7
tré est laissé à 370 C environ La fin de la fermentation est confirmée avec un appareil de The end of the fermentation is confirmed with an apparatus of
Conway en prélevant des échantillons de liquide de 0,5 ml chacun du liquide filtré et en mé- Conway by taking liquid samples of 0.5 ml each from the filtered liquid and
langeant chaque échantillon avec 1 mi de carbonate de potassium se trouvant dans ledit appa- languishing each sample with 1 ml of potassium carbonate in the same
reil La fin de la fermentation est connue par observation des changements dans les quantités d'ammoniac se volatilisant, ceci par dosage La fin de la fermentation est confirmée après 10 heures approximativement Le liquide ainsi obtenu est filtré de la manière habituelle et l'on The end of the fermentation is known by observing the changes in the quantities of ammonia volatilizing, this by dosage The end of the fermentation is confirmed after approximately 10 hours The liquid thus obtained is filtered in the usual manner and
obtient une lotion capillaire nutritive. gets a nutritive hair lotion.
Evaluation des résultats Les liquides capillaires nutritifs obtenus selon les exemples 1 à 4 ont été dilués avec de l'éthanol et les mélanges ont été appliqués sur des hommes et sur des souris tous les jours, une fois le matin et une fois le soir Après 30 jours d'application, les deux types de témoins présentaient des résultats étonnants quant à la croissance et à la repousse des cheveux Dans Evaluation of the results The nutritive capillary liquids obtained according to Examples 1 to 4 were diluted with ethanol and the mixtures were applied to men and mice daily, once in the morning and once in the evening. days of application, both types of controls showed surprising results in hair growth and regrowth.
le cas des souris tout particulièrement, l'influence sur la poussée des cheveux était énorme. the case of the mice in particular, the influence on the thrust of the hair was enormous.
Claims (1)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP31611091 | 1991-11-29 |
Publications (2)
Publication Number | Publication Date |
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FR2684295A1 true FR2684295A1 (en) | 1993-06-04 |
FR2684295B1 FR2684295B1 (en) | 1995-05-19 |
Family
ID=18073362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9201361A Expired - Fee Related FR2684295B1 (en) | 1991-11-29 | 1992-01-31 | NUTRITIONAL COMPOSITION FOR HAIR USE AND PROCESS FOR PREPARING THE SAME. |
Country Status (19)
Country | Link |
---|---|
KR (1) | KR0160141B1 (en) |
CN (1) | CN1053098C (en) |
AT (1) | AT405016B (en) |
AU (1) | AU663301B2 (en) |
CA (1) | CA2059314C (en) |
CH (1) | CH683317A5 (en) |
DE (1) | DE4202645A1 (en) |
DK (1) | DK292A (en) |
FI (1) | FI920035A (en) |
FR (1) | FR2684295B1 (en) |
GB (1) | GB2261818B (en) |
HK (1) | HK496A (en) |
IT (1) | IT1254612B (en) |
MY (1) | MY107936A (en) |
NL (1) | NL9200160A (en) |
NO (1) | NO920202L (en) |
NZ (1) | NZ241290A (en) |
PH (1) | PH30444A (en) |
ZA (1) | ZA92186B (en) |
Cited By (1)
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FR2951944A1 (en) * | 2009-11-03 | 2011-05-06 | Isp Investments Inc | USE OF A COMPOSITION COMPRISING A PEPTIDE HYDROLYZATE OF NON-FERMENTENT RICE FOR STIMULATING HAIR GROWTH. |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9909294D0 (en) * | 1999-04-22 | 1999-06-16 | Unilever Plc | Treating hair by targeting enzymes |
JP2000327538A (en) * | 1999-05-24 | 2000-11-28 | Toyo Hakko:Kk | Agent composition for hair treatment |
EP1500386A1 (en) * | 2003-07-23 | 2005-01-26 | Wella Aktiengesellschaft | Method for time-dependent decrease of ph in a cosmetic composition and a composition for permanent hair shaping with time-dependent decrease of the wave-shaping efficiency |
KR20050041573A (en) * | 2003-10-31 | 2005-05-04 | 김민호 | Composition for straight permanent of gel type |
JP5315992B2 (en) * | 2006-06-08 | 2013-10-16 | 味の素株式会社 | Hair growth composition |
FR2963234B1 (en) | 2010-07-29 | 2020-07-17 | Isp Investments Inc | USE OF A COMPOSITION COMPRISING A PEPTIDE EXTRACT OF BEANS FOR STIMULATING HAIR GROWTH |
CN105125475A (en) * | 2015-09-27 | 2015-12-09 | 常州市奥普泰科光电有限公司 | Cosmetic film-forming moisture preserving additive |
CN112022792B (en) * | 2020-09-27 | 2022-12-09 | 黑龙江省中医药科学院 | Preparation method of edible traditional Chinese medicine hair dye with homology of medicine and food |
DE102020125874A1 (en) * | 2020-10-02 | 2022-04-07 | Dr. Kurt Wolff Gmbh & Co. Kg | Hair and skin treatment composition |
DE102020125876A1 (en) * | 2020-10-02 | 2022-04-07 | Dr. Kurt Wolff Gmbh & Co. Kg | Hair and scalp treatment composition |
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FR1268459A (en) * | 1959-05-05 | 1961-08-04 | Product for the treatment of the scalp and hair and process for the preparation thereof | |
FR1363121A (en) * | 1961-12-19 | 1964-06-12 | Hygienic-dietetic method for preventing baldness and in particular seborrheic alopecia | |
FR2072694A5 (en) * | 1969-12-05 | 1971-09-24 | Dragoco Gerberding Co Gmbh | Plant extract non-dissociable by fermenta- - tion for dilution with water or alcohol |
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EP0117087A1 (en) * | 1983-02-02 | 1984-08-29 | Suntory Limited | Hair tonic composition |
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CH367937A (en) * | 1958-05-23 | 1963-03-15 | Dubois Raymond | Process for preparing a product for treating the scalp and hair |
US3395019A (en) * | 1965-10-18 | 1968-07-30 | Vylactos Lab Inc | Preparation of animal feed from oat hulls |
JPS51151396A (en) * | 1975-06-18 | 1976-12-25 | Kikkoman Corp | Process for preparing solid koji |
JPS5356394A (en) * | 1976-10-28 | 1978-05-22 | Fukushima Hiroo | Liquid flavoring and process for preparing same |
JPS59134710A (en) * | 1983-01-21 | 1984-08-02 | Suntory Ltd | Hair tonic from fermentation product |
US4548939A (en) * | 1984-10-01 | 1985-10-22 | Janssen Pharmaceutica N. V. | 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones |
DE3445919A1 (en) * | 1984-12-17 | 1986-06-19 | Henkel KGaA, 4000 Düsseldorf | COSMETIC PREPARATION WITH ALMOND PROTEIN HYDROLYSATE |
JP2640349B2 (en) * | 1987-10-15 | 1997-08-13 | 株式会社三光生物科学研究所 | Hair restoration |
JPH01128912A (en) * | 1987-11-13 | 1989-05-22 | Shogo Ogura | Production of hair dressing and growing agent |
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- 1992-01-02 DK DK000292A patent/DK292A/en not_active Application Discontinuation
- 1992-01-03 FI FI920035A patent/FI920035A/en unknown
- 1992-01-10 ZA ZA92186A patent/ZA92186B/en unknown
- 1992-01-13 NZ NZ241290A patent/NZ241290A/en unknown
- 1992-01-14 PH PH43776A patent/PH30444A/en unknown
- 1992-01-14 MY MYPI92000058A patent/MY107936A/en unknown
- 1992-01-14 AU AU10211/92A patent/AU663301B2/en not_active Ceased
- 1992-01-14 CA CA002059314A patent/CA2059314C/en not_active Expired - Fee Related
- 1992-01-16 NO NO92920202A patent/NO920202L/en unknown
- 1992-01-17 GB GB9200976A patent/GB2261818B/en not_active Expired - Fee Related
- 1992-01-25 KR KR1019920001091A patent/KR0160141B1/en not_active IP Right Cessation
- 1992-01-29 NL NL9200160A patent/NL9200160A/en not_active Application Discontinuation
- 1992-01-30 DE DE4202645A patent/DE4202645A1/en not_active Withdrawn
- 1992-01-31 FR FR9201361A patent/FR2684295B1/en not_active Expired - Fee Related
- 1992-01-31 CN CN92100775A patent/CN1053098C/en not_active Expired - Fee Related
- 1992-02-06 CH CH339/92A patent/CH683317A5/en not_active IP Right Cessation
- 1992-02-18 IT ITMI920349A patent/IT1254612B/en active IP Right Grant
- 1992-02-24 AT AT0034392A patent/AT405016B/en not_active IP Right Cessation
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FR1363121A (en) * | 1961-12-19 | 1964-06-12 | Hygienic-dietetic method for preventing baldness and in particular seborrheic alopecia | |
FR2072694A5 (en) * | 1969-12-05 | 1971-09-24 | Dragoco Gerberding Co Gmbh | Plant extract non-dissociable by fermenta- - tion for dilution with water or alcohol |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2951944A1 (en) * | 2009-11-03 | 2011-05-06 | Isp Investments Inc | USE OF A COMPOSITION COMPRISING A PEPTIDE HYDROLYZATE OF NON-FERMENTENT RICE FOR STIMULATING HAIR GROWTH. |
FR2951947A1 (en) * | 2009-11-03 | 2011-05-06 | Isp Investments Inc | USE OF A COMPOSITION COMPRISING A PEPTIDE EXTRACT OF NON-FERMENTENT RICE FOR STIMULATING HAIR GROWTH |
WO2011055032A2 (en) | 2009-11-03 | 2011-05-12 | Isp Investments Inc. | Use of a composition comprising a non-fermented rice peptide hydrolysate for stimulating hair growth |
WO2011055032A3 (en) * | 2009-11-03 | 2011-06-30 | Isp Investments Inc. | Use of a composition comprising a non-fermented rice peptide hydrolysate for stimulating hair growth |
US8541374B2 (en) | 2009-11-03 | 2013-09-24 | Isp Investments Inc. | Use of a composition comprising a non-fermented rice peptidic hydrolyzate for stimulating hair growth |
Also Published As
Publication number | Publication date |
---|---|
GB2261818A (en) | 1993-06-02 |
CH683317A5 (en) | 1994-02-28 |
FI920035A0 (en) | 1992-01-03 |
ATA34392A (en) | 1998-09-15 |
NL9200160A (en) | 1993-06-16 |
IT1254612B (en) | 1995-09-28 |
CN1072588A (en) | 1993-06-02 |
NO920202D0 (en) | 1992-01-16 |
CA2059314A1 (en) | 1993-05-30 |
AU663301B2 (en) | 1995-10-05 |
GB9200976D0 (en) | 1992-03-11 |
DE4202645A1 (en) | 1993-06-03 |
KR930009589A (en) | 1993-06-21 |
NZ241290A (en) | 1993-10-26 |
AU1021192A (en) | 1993-06-03 |
NO920202L (en) | 1993-06-01 |
AT405016B (en) | 1999-04-26 |
FR2684295B1 (en) | 1995-05-19 |
DK292D0 (en) | 1992-01-02 |
FI920035A (en) | 1993-05-30 |
ZA92186B (en) | 1992-09-30 |
HK496A (en) | 1996-01-12 |
DK292A (en) | 1992-01-02 |
MY107936A (en) | 1996-06-29 |
PH30444A (en) | 1997-05-09 |
CA2059314C (en) | 1999-03-30 |
GB2261818B (en) | 1995-09-27 |
CN1053098C (en) | 2000-06-07 |
ITMI920349A0 (en) | 1992-02-18 |
ITMI920349A1 (en) | 1993-08-18 |
KR0160141B1 (en) | 1998-12-01 |
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