FR2678614A1 - Compose presentant une activite en tant qu'inhibiteur de la collagenase et medicament le contenant. - Google Patents
Compose presentant une activite en tant qu'inhibiteur de la collagenase et medicament le contenant. Download PDFInfo
- Publication number
- FR2678614A1 FR2678614A1 FR9108303A FR9108303A FR2678614A1 FR 2678614 A1 FR2678614 A1 FR 2678614A1 FR 9108303 A FR9108303 A FR 9108303A FR 9108303 A FR9108303 A FR 9108303A FR 2678614 A1 FR2678614 A1 FR 2678614A1
- Authority
- FR
- France
- Prior art keywords
- compounds
- furanyl
- formula
- oil
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/17—Saturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/24—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/003—Esters of saturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/36—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9108303A FR2678614A1 (fr) | 1991-07-03 | 1991-07-03 | Compose presentant une activite en tant qu'inhibiteur de la collagenase et medicament le contenant. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9108303A FR2678614A1 (fr) | 1991-07-03 | 1991-07-03 | Compose presentant une activite en tant qu'inhibiteur de la collagenase et medicament le contenant. |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2678614A1 true FR2678614A1 (fr) | 1993-01-08 |
FR2678614B1 FR2678614B1 (de) | 1995-03-03 |
Family
ID=9414656
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9108303A Granted FR2678614A1 (fr) | 1991-07-03 | 1991-07-03 | Compose presentant une activite en tant qu'inhibiteur de la collagenase et medicament le contenant. |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2678614A1 (de) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0775480A1 (de) * | 1993-10-25 | 1997-05-28 | S. Richard Huber | Lipidische Furane und ihre Anwendung als Hauttherapeutika |
WO1999055657A1 (fr) * | 1998-04-29 | 1999-11-04 | Laboratoires Pharmascience | Nouveaux composes extraits d'huile vegetale utilisables dans l'industrie pharmaceutique et cosmetique, notamment pour l'inhibition de la croissance cellulaire |
FR2798667A1 (fr) * | 1999-09-22 | 2001-03-23 | Pharmascience Lab | Procede d'extraction des composes furaniques et alcools gras polyhydroxyles de l'avocat, composition a base de et utilisation de ces composes en therapeutique, cosmetique et alimentaire |
WO2004012496A2 (fr) * | 2002-07-29 | 2004-02-12 | Laboratoires Expanscience | Procede d'obtention d'un insaponifiable d'avocat riche en lipides furaniques |
FR2870742A1 (fr) * | 2004-05-28 | 2005-12-02 | Expanscience Laboratoires Sa | Utilisation d'alkyle furannes pour la preparation d'un medicament destine au traitement du diabete, de l'obesite et pour le traitement cosmetique de la cellulite et de la surcharge ponderale |
US7589121B2 (en) | 2004-05-28 | 2009-09-15 | Laboratoires Expanscience | Use of furan alkyls for preparing a drug for treating obesity and cosmetically treating overweight |
US7872043B2 (en) | 2004-05-28 | 2011-01-18 | Laboratories Expanscience | Use of furan alkyls for a cellulite cosmetic treatment |
JP2016515585A (ja) * | 2013-03-29 | 2016-05-30 | アボサイエンス、リミテッド、ライアビリティー、カンパニーAvoscience, Llc | 癌、神経障害及び線維性障害の治療のための、脂質フラン、ピロール及びチオフェン化合物 |
US10905673B2 (en) | 2016-04-27 | 2021-02-02 | Avoscience, Llc | Lipidic furan, pyrrole, and thiophene compounds for use in the treatment of atrophic vaginitis |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1425343A (en) * | 1972-02-14 | 1976-02-18 | Unilever Ltd | Phthalic acid derivatives |
-
1991
- 1991-07-03 FR FR9108303A patent/FR2678614A1/fr active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1425343A (en) * | 1972-02-14 | 1976-02-18 | Unilever Ltd | Phthalic acid derivatives |
Non-Patent Citations (5)
Title |
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CHEMICAL ABSTRACTS, vol. 103, no. 19, 11 Novembre 1985, Columbus, Ohio, US; abstract no. 157333D, L. PREVITERA ET AL.: 'Acetogenins from the aquatic plant Elodea canadensis' page 411 ;colonne 2 ; * |
CHEMICAL ABSTRACTS, vol. 105, no. 21, 24 Novembre 1986, Columbus, Ohio, US; abstract no. 187627M, D. MEROLA: 'Elodea canadensis metabolites' page 421 ;colonne 1 ; * |
CHEMICAL ABSTRACTS, vol. 115, no. 21, 25 Novembre 1991, Columbus, Ohio, US; abstract no. 232007D, ULKU OYMAN: 'Dehydration of some 1-(2-furyl) and 1-(2-thienyl)-1-alkanols using cobalt(II) sulfate as catalyst' page 924 ;colonne 2 ; * |
CHEMICAL ABSTRACTS, vol. 72, no. 25, 22 Juin 1970, Columbus, Ohio, US; abstract no. 129380Q, L. NEEMAN ET AL.: 'New antibacterial agent isolated from the avocado pear' page 75 ;colonne 1 ; * |
CHEMICAL ABSTRACTS, vol. 75, no. 19, 8 Novembre 1971, Columbus, Ohio, US; abstract no. 115910N, H. M. ALVES ET AL.: 'Avocatins. New class of natural products' page 27 ;colonne 2 ; * |
Cited By (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0775480A1 (de) * | 1993-10-25 | 1997-05-28 | S. Richard Huber | Lipidische Furane und ihre Anwendung als Hauttherapeutika |
WO1999055657A1 (fr) * | 1998-04-29 | 1999-11-04 | Laboratoires Pharmascience | Nouveaux composes extraits d'huile vegetale utilisables dans l'industrie pharmaceutique et cosmetique, notamment pour l'inhibition de la croissance cellulaire |
FR2778181A1 (fr) * | 1998-04-29 | 1999-11-05 | Pharmascience Lab | Nouveaux composes extraits d'huile vegetale utilisables dans l'industrie pharmaceutique et cosmetique,notamment pour l'inhibition de la croissance cellulaire |
JP2003509506A (ja) * | 1999-09-22 | 2003-03-11 | ラボラトワール ファルマシアンス | アボガドのフラン脂質化合物およびポリヒドロキシル化された脂肪族アルコールを抽出する方法、該化合物に基く組成物および治療、美容並びに食品における該化合物の使用 |
WO2001021605A2 (fr) * | 1999-09-22 | 2001-03-29 | Laboratoires Pharmascience | Procede d'extraction des composes lipides furaniques et alcools gras polyhydroxyles de l'avocat, composition a base de ces composes et leur utilisation en therapeutique, cosmetique et alimentaire |
WO2001021605A3 (fr) * | 1999-09-22 | 2001-10-25 | Pharmascience Lab | Procede d'extraction des composes lipides furaniques et alcools gras polyhydroxyles de l'avocat, composition a base de ces composes et leur utilisation en therapeutique, cosmetique et alimentaire |
US6582688B1 (en) | 1999-09-22 | 2003-06-24 | Pharmascience | Method for extracting compounds of furan lipids and polyhydroxylated fatty alcohols of avocado, composition based on said compounds, and therapeutic, cosmetical or food use of said compounds |
JP5021879B2 (ja) * | 1999-09-22 | 2012-09-12 | ラボラトワール エクスパンシアンス | アボガドのフラン脂質化合物およびポリヒドロキシル化された脂肪族アルコールを抽出する方法、該化合物に基く組成物および治療、美容並びに食品における該化合物の使用 |
FR2798667A1 (fr) * | 1999-09-22 | 2001-03-23 | Pharmascience Lab | Procede d'extraction des composes furaniques et alcools gras polyhydroxyles de l'avocat, composition a base de et utilisation de ces composes en therapeutique, cosmetique et alimentaire |
US7371420B2 (en) | 2002-07-29 | 2008-05-13 | Laboratoires Expanscience | Method for producing an avocado unsaponifiable rich in furan lipids |
WO2004012496A2 (fr) * | 2002-07-29 | 2004-02-12 | Laboratoires Expanscience | Procede d'obtention d'un insaponifiable d'avocat riche en lipides furaniques |
WO2004016106A1 (fr) * | 2002-07-29 | 2004-02-26 | Laboratoires Expanscience | Procede d'obtention d'un insaponifiable d'avocat riche en lipides furaniques |
WO2004012496A3 (fr) * | 2002-07-29 | 2004-04-08 | Expanscience Lab | Procede d'obtention d'un insaponifiable d'avocat riche en lipides furaniques |
WO2005117856A1 (fr) * | 2004-05-28 | 2005-12-15 | Laboratoires Expanscience | Utilisation d’alkyle furannes pour la preparation d’un medicament destine au traitement du diabete |
US7589121B2 (en) | 2004-05-28 | 2009-09-15 | Laboratoires Expanscience | Use of furan alkyls for preparing a drug for treating obesity and cosmetically treating overweight |
CN1960722B (zh) * | 2004-05-28 | 2010-09-08 | 科学发展实验室 | 烷基呋喃在制备抗糖尿病药物中的用途 |
US7872043B2 (en) | 2004-05-28 | 2011-01-18 | Laboratories Expanscience | Use of furan alkyls for a cellulite cosmetic treatment |
FR2870742A1 (fr) * | 2004-05-28 | 2005-12-02 | Expanscience Laboratoires Sa | Utilisation d'alkyle furannes pour la preparation d'un medicament destine au traitement du diabete, de l'obesite et pour le traitement cosmetique de la cellulite et de la surcharge ponderale |
US8859617B2 (en) | 2004-05-28 | 2014-10-14 | Laboratoires Expanscience | Use of furan alkyl for preparing an antidiabetic drug |
JP2016515585A (ja) * | 2013-03-29 | 2016-05-30 | アボサイエンス、リミテッド、ライアビリティー、カンパニーAvoscience, Llc | 癌、神経障害及び線維性障害の治療のための、脂質フラン、ピロール及びチオフェン化合物 |
US10085962B2 (en) | 2013-03-29 | 2018-10-02 | Avoscience, Llc | Lipidic furan, pyrrole, and thiophene compounds for treatment of cancer, neurological disorders, and fibrotic disorders |
US10525031B2 (en) | 2013-03-29 | 2020-01-07 | Avoscience, Llc | Lipid furan, pyrrole, and thiophene compounds for treatment of cancer, neurological disorders, and fibrotic disorders |
US11058663B2 (en) | 2013-03-29 | 2021-07-13 | Avoscience, Llc | Lipidic furan, pyrrole, and thiophene compounds for treatment of cancer, neurological disorders, and fibrotic disorders |
US11833129B2 (en) | 2013-03-29 | 2023-12-05 | Avoscience, Llc | Thiophene compound for treatment of exfoliating glaucoma |
US10905673B2 (en) | 2016-04-27 | 2021-02-02 | Avoscience, Llc | Lipidic furan, pyrrole, and thiophene compounds for use in the treatment of atrophic vaginitis |
US11602518B2 (en) | 2016-04-27 | 2023-03-14 | Avoscience, Llc | Lipidic furan, pyrrole, and thiophene compounds for use in the treatment of atrophic vaginitis |
Also Published As
Publication number | Publication date |
---|---|
FR2678614B1 (de) | 1995-03-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CD | Change of name or company name |