FR2673952A1 - Moyens pour le diagnostic in vitro de constituants de granules cytoplasmiques et applications biologiques. - Google Patents

Moyens pour le diagnostic in vitro de constituants de granules cytoplasmiques et applications biologiques. Download PDF

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Publication number
FR2673952A1
FR2673952A1 FR9103108A FR9103108A FR2673952A1 FR 2673952 A1 FR2673952 A1 FR 2673952A1 FR 9103108 A FR9103108 A FR 9103108A FR 9103108 A FR9103108 A FR 9103108A FR 2673952 A1 FR2673952 A1 FR 2673952A1
Authority
FR
France
Prior art keywords
cells
perforin
antibodies
granzyme
monoclonal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR9103108A
Other languages
English (en)
French (fr)
Other versions
FR2673952B1 (enrdf_load_stackoverflow
Inventor
Sasportes Marilyne
Tschopp Jurg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Priority to FR9103108A priority Critical patent/FR2673952A1/fr
Priority to JP4508582A priority patent/JPH06506112A/ja
Priority to EP19920909090 priority patent/EP0575539A1/fr
Priority to CA 2106193 priority patent/CA2106193A1/fr
Priority to PCT/FR1992/000240 priority patent/WO1992016644A1/fr
Publication of FR2673952A1 publication Critical patent/FR2673952A1/fr
Application granted granted Critical
Publication of FR2673952B1 publication Critical patent/FR2673952B1/fr
Granted legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6467Granzymes, e.g. granzyme A (3.4.21.78); granzyme B (3.4.21.79)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
FR9103108A 1991-03-14 1991-03-14 Moyens pour le diagnostic in vitro de constituants de granules cytoplasmiques et applications biologiques. Granted FR2673952A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR9103108A FR2673952A1 (fr) 1991-03-14 1991-03-14 Moyens pour le diagnostic in vitro de constituants de granules cytoplasmiques et applications biologiques.
JP4508582A JPH06506112A (ja) 1991-03-14 1992-03-16 細胞質顆粒構成成分のインビトロ診断のための手段及びその生物学的応用
EP19920909090 EP0575539A1 (fr) 1991-03-14 1992-03-16 Moyens pour le diagnostic in vitro de constituants de granules cytoplasmiques et applications biologiques
CA 2106193 CA2106193A1 (fr) 1991-03-14 1992-03-16 Moyens pour le diagnostic in vitro de constituants de granules cytoplasmiques et applications biologiques
PCT/FR1992/000240 WO1992016644A1 (fr) 1991-03-14 1992-03-16 Moyens pour le diagnostic in vitro de constituants de granules cytoplasmiques et applications biologiques

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9103108A FR2673952A1 (fr) 1991-03-14 1991-03-14 Moyens pour le diagnostic in vitro de constituants de granules cytoplasmiques et applications biologiques.

Publications (2)

Publication Number Publication Date
FR2673952A1 true FR2673952A1 (fr) 1992-09-18
FR2673952B1 FR2673952B1 (enrdf_load_stackoverflow) 1995-05-12

Family

ID=9410734

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9103108A Granted FR2673952A1 (fr) 1991-03-14 1991-03-14 Moyens pour le diagnostic in vitro de constituants de granules cytoplasmiques et applications biologiques.

Country Status (5)

Country Link
EP (1) EP0575539A1 (enrdf_load_stackoverflow)
JP (1) JPH06506112A (enrdf_load_stackoverflow)
CA (1) CA2106193A1 (enrdf_load_stackoverflow)
FR (1) FR2673952A1 (enrdf_load_stackoverflow)
WO (1) WO1992016644A1 (enrdf_load_stackoverflow)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2887060B2 (ja) * 1993-06-30 1999-04-26 日清製粉株式会社 グリセンチンの生産方法
US5858758A (en) * 1997-05-07 1999-01-12 Incyte Pharmaceuticals, Inc. Human serine protease precursor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783410A (en) * 1985-06-28 1988-11-08 Massachusetts Institute Of Technology Cytotoxic t lymphocyte serine esterase and method for stimulation and inhibition
EP0245051B1 (en) * 1986-05-06 1992-08-12 The Board Of Trustees Of The Leland Stanford Junior University Killer cell cytotoxic composition

Also Published As

Publication number Publication date
WO1992016644A1 (fr) 1992-10-01
EP0575539A1 (fr) 1993-12-29
CA2106193A1 (fr) 1992-09-15
JPH06506112A (ja) 1994-07-14
FR2673952B1 (enrdf_load_stackoverflow) 1995-05-12

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Legal Events

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ER Errata listed in the french official journal (bopi)

Free format text: 38/92

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