FR2657881A1 - Nouveaux polypeptides hydrosolubles, sequences d'adn, nouvelles cellules, procede de preparation, applications et compositions renfermant lesdits polypeptides. - Google Patents

Nouveaux polypeptides hydrosolubles, sequences d'adn, nouvelles cellules, procede de preparation, applications et compositions renfermant lesdits polypeptides. Download PDF

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Publication number
FR2657881A1
FR2657881A1 FR9001298A FR9001298A FR2657881A1 FR 2657881 A1 FR2657881 A1 FR 2657881A1 FR 9001298 A FR9001298 A FR 9001298A FR 9001298 A FR9001298 A FR 9001298A FR 2657881 A1 FR2657881 A1 FR 2657881A1
Authority
FR
France
Prior art keywords
soluble
receptor
water
interferon
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR9001298A
Other languages
English (en)
French (fr)
Other versions
FR2657881B1 (https=
Inventor
Eid Pierre
Gresser Ion
Lutfalla Georges
Meyer Francois
Mogensen Knud Erik
Michael G Tovey
Uze Gilles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EUROP BIOTECHNOLOGIE LAB
Original Assignee
EUROP BIOTECHNOLOGIE LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EUROP BIOTECHNOLOGIE LAB filed Critical EUROP BIOTECHNOLOGIE LAB
Priority to FR9001298A priority Critical patent/FR2657881A1/fr
Priority to HU9203955A priority patent/HU215587B/hu
Publication of FR2657881A1 publication Critical patent/FR2657881A1/fr
Application granted granted Critical
Publication of FR2657881B1 publication Critical patent/FR2657881B1/fr
Granted legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9001298A 1990-02-05 1990-02-05 Nouveaux polypeptides hydrosolubles, sequences d'adn, nouvelles cellules, procede de preparation, applications et compositions renfermant lesdits polypeptides. Granted FR2657881A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR9001298A FR2657881A1 (fr) 1990-02-05 1990-02-05 Nouveaux polypeptides hydrosolubles, sequences d'adn, nouvelles cellules, procede de preparation, applications et compositions renfermant lesdits polypeptides.
HU9203955A HU215587B (hu) 1990-02-05 1991-04-17 Eljárás alfa- és béta-interferonokkal szemben nagy affinitással rendelkező vízoldható polipeptidek, az azokat kódoló DNS-szekvenciák, a polipeptideket kifejezni képes sejtek és a polipeptideket tartalmazó gyógyászati készítmények előállítására

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9001298A FR2657881A1 (fr) 1990-02-05 1990-02-05 Nouveaux polypeptides hydrosolubles, sequences d'adn, nouvelles cellules, procede de preparation, applications et compositions renfermant lesdits polypeptides.

Publications (2)

Publication Number Publication Date
FR2657881A1 true FR2657881A1 (fr) 1991-08-09
FR2657881B1 FR2657881B1 (https=) 1994-08-19

Family

ID=9393388

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9001298A Granted FR2657881A1 (fr) 1990-02-05 1990-02-05 Nouveaux polypeptides hydrosolubles, sequences d'adn, nouvelles cellules, procede de preparation, applications et compositions renfermant lesdits polypeptides.

Country Status (2)

Country Link
FR (1) FR2657881A1 (https=)
HU (1) HU215587B (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992018626A1 (fr) * 1991-04-17 1992-10-29 Laboratoire Europeen De Biotechnologie POLYPEPTIDES HYDROSOLUBLES AYANT UNE HAUTE AFFINITE POUR LES INTERFERONS α ET $g(b)
EP0588177A3 (en) * 1992-09-03 1994-08-17 Yeda Res & Dev An interferon-alpha/beta binding protein, its preparation and pharmaceutical compositions containing it
US5821078A (en) * 1992-09-03 1998-10-13 Yeda Research And Development Co. Ltd. Nucleic acid encoding interferon-α/β binding protein
US6429186B1 (en) 1991-05-10 2002-08-06 Genentech, Inc. Ligand antagonists for treatment of breast cancer
EP1329459A3 (en) * 1992-03-31 2003-09-10 Medisup International N.V. Monoclonal antibodies against the interferon receptor, with neutralizing activity against type I interferon
US7087726B2 (en) 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CELL, vol. 60, janvier 1990, pages 225-234, Cell Press; G. UZE et al.: "Genetic transfer of a functional human interferon alpha receptor into mouse cells: Cloning and expression of its cDNA" *
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES USA, vol. 80, juin 1983, pages 3269-3273; C.R. FALTYNEK et al.: "Characterization of an interferon receptor on human lymphoblastoid cells" *
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES USA, vol. 80, mai 1983, pages 2539-2543; H. ARNHEITER et al.: "Orientation of a human leukocyte interferon molecule on its cell surface receptor: Carboxyl terminus remains accessible to a monoclonal antibody made against a synthetic interferon fragment" *

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992018626A1 (fr) * 1991-04-17 1992-10-29 Laboratoire Europeen De Biotechnologie POLYPEPTIDES HYDROSOLUBLES AYANT UNE HAUTE AFFINITE POUR LES INTERFERONS α ET $g(b)
US6475983B1 (en) 1991-04-17 2002-11-05 Medisup International N.V. Water-soluble polypeptides having a high affinity for α and β interferons
US6429186B1 (en) 1991-05-10 2002-08-06 Genentech, Inc. Ligand antagonists for treatment of breast cancer
EP1329459A3 (en) * 1992-03-31 2003-09-10 Medisup International N.V. Monoclonal antibodies against the interferon receptor, with neutralizing activity against type I interferon
US6787634B2 (en) * 1992-03-31 2004-09-07 Medisup International, N.V. Isolated peptide or polypeptide of the extracellular portion of the human interferon receptor (IFN-R).
US7465451B2 (en) 1992-03-31 2008-12-16 Medarex, Inc. Monoclonal antibodies against the interferon receptor, with neutralizing activity against type I interferon
US6458932B1 (en) 1992-09-03 2002-10-01 Yeda Research And Development Co. Ltd. Interferon-α/β binding protein, its preparation and use
US5821078A (en) * 1992-09-03 1998-10-13 Yeda Research And Development Co. Ltd. Nucleic acid encoding interferon-α/β binding protein
EP0588177A3 (en) * 1992-09-03 1994-08-17 Yeda Res & Dev An interferon-alpha/beta binding protein, its preparation and pharmaceutical compositions containing it
US7087726B2 (en) 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies
US7582445B2 (en) 2001-02-22 2009-09-01 Genentech, Inc. Anti-interferon-α antibodies
US7910707B2 (en) 2001-02-22 2011-03-22 Genentech, Inc. Anti-interferon-α antibodies
US8349331B2 (en) 2001-02-22 2013-01-08 Genentech, Inc. Anti-interferon-α antibodies
US8557967B2 (en) 2001-02-22 2013-10-15 Genentech, Inc. Anti-interferon-α antibodies

Also Published As

Publication number Publication date
HU9203955D0 (en) 1993-03-29
FR2657881B1 (https=) 1994-08-19
HU215587B (hu) 1999-01-28
HUT65413A (en) 1994-06-28

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