FR2657260B1 - Procede et composition permettant de purifier l'amphotericine b.. - Google Patents

Procede et composition permettant de purifier l'amphotericine b..

Info

Publication number
FR2657260B1
FR2657260B1 FR909000722A FR9000722A FR2657260B1 FR 2657260 B1 FR2657260 B1 FR 2657260B1 FR 909000722 A FR909000722 A FR 909000722A FR 9000722 A FR9000722 A FR 9000722A FR 2657260 B1 FR2657260 B1 FR 2657260B1
Authority
FR
France
Prior art keywords
amphotericin
purifying
composition
purifying amphotericin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR909000722A
Other languages
English (en)
Other versions
FR2657260A1 (fr
Inventor
Gerd W Michel
Wilbur L Bryan
Bryan Elizabeth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2657260A1 publication Critical patent/FR2657260A1/fr
Application granted granted Critical
Publication of FR2657260B1 publication Critical patent/FR2657260B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR909000722A 1987-10-27 1990-01-23 Procede et composition permettant de purifier l'amphotericine b.. Expired - Lifetime FR2657260B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/113,790 US4902789A (en) 1987-10-27 1987-10-27 Process and composition for the purification of amphotericin B
CA002007367A CA2007367C (fr) 1987-10-27 1990-01-09 Procede et composition pour la purification de l'amphotericine b
CN90100998A CN1029617C (zh) 1987-10-27 1990-01-31 纯化与结晶两性霉素b的方法

Publications (2)

Publication Number Publication Date
FR2657260A1 FR2657260A1 (fr) 1991-07-26
FR2657260B1 true FR2657260B1 (fr) 1992-04-24

Family

ID=36754226

Family Applications (1)

Application Number Title Priority Date Filing Date
FR909000722A Expired - Lifetime FR2657260B1 (fr) 1987-10-27 1990-01-23 Procede et composition permettant de purifier l'amphotericine b..

Country Status (8)

Country Link
US (1) US4902789A (fr)
JP (1) JPH03240793A (fr)
CN (1) CN1029617C (fr)
CA (1) CA2007367C (fr)
DE (1) DE4002351A1 (fr)
FR (1) FR2657260B1 (fr)
GB (1) GB2239653B (fr)
HU (1) HU205768B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8404217B2 (en) * 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US8648050B2 (en) * 2002-10-03 2014-02-11 University Of Mississippi Methods and formulations for reducing amphotericin B treatment side effects
DE60320283T2 (de) * 2002-10-03 2009-08-27 University of Mississippi, University Zusammensetzungen mit Amphotericin B enthaltend weniger als 4% Verunreinigungen
US7776831B2 (en) 2006-02-01 2010-08-17 Weg Stuart L Use of antifungal compositions to treat upper gastrointestinal conditions
CN102746352B (zh) * 2011-04-20 2016-03-30 上海新亚药业有限公司 一种治疗深部真菌感染药物的纯化工艺
CN112175029A (zh) * 2019-07-01 2021-01-05 刘力 抗真菌的大环多烯类新化合物
CN114605484A (zh) * 2020-12-09 2022-06-10 上海上药新亚药业有限公司 一种获得两性霉素b新晶型的纯化方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2908611A (en) * 1954-12-28 1959-10-13 Olin Mathieson Amphotericin b, its production, and its salts
FR2173632A1 (en) * 1971-02-04 1973-10-12 Le N Iss Purificn of amfotericin b - in dmf soln by adding water acidifying filtering adding water,making alkaline and washing
CH556879A (de) * 1971-04-23 1974-12-13 Le Nii Antibiotikov Verfahren zur gewinnung und chemischen reinigung von amphoterizin b.
US3965090A (en) * 1973-03-05 1976-06-22 E. R. Squibb & Sons, Inc. Amphotericin complexes
US4049898A (en) * 1973-03-05 1977-09-20 E. R. Squibb & Sons, Inc. Amphotericin complexes containing oxalic acid and calcium
DE2500731A1 (de) * 1975-01-10 1976-07-15 Magg Einrichtung zum spannen von tauen, seilen oder draehten
US4054734A (en) * 1975-03-03 1977-10-18 E. R. Squibb & Sons, Inc. Amphotericin complexes containing citric acid and calcium
US4177265A (en) * 1977-03-02 1979-12-04 E. R. Squibb & Sons, Inc. Process for the purification of amphotericin B and A solubilizing media useful in that process
US4308375A (en) * 1980-10-06 1981-12-29 E. R. Squibb & Sons, Inc. Method for purifying water-insoluble polyene antibiotics

Also Published As

Publication number Publication date
CA2007367C (fr) 2000-03-14
GB9000357D0 (en) 1990-03-07
HU900124D0 (en) 1990-03-28
JPH03240793A (ja) 1991-10-28
CA2007367A1 (fr) 1991-07-09
CN1029617C (zh) 1995-08-30
FR2657260A1 (fr) 1991-07-26
HUT56377A (en) 1991-08-28
GB2239653A (en) 1991-07-10
GB2239653B (en) 1993-06-23
HU205768B (en) 1992-06-29
CN1053794A (zh) 1991-08-14
DE4002351A1 (de) 1991-08-01
US4902789A (en) 1990-02-20

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20060929