FR2639350B1 - Radical nitroxyde, son procede de fabrication et son application en magnetometrie - Google Patents
Radical nitroxyde, son procede de fabrication et son application en magnetometrieInfo
- Publication number
- FR2639350B1 FR2639350B1 FR8815107A FR8815107A FR2639350B1 FR 2639350 B1 FR2639350 B1 FR 2639350B1 FR 8815107 A FR8815107 A FR 8815107A FR 8815107 A FR8815107 A FR 8815107A FR 2639350 B1 FR2639350 B1 FR 2639350B1
- Authority
- FR
- France
- Prior art keywords
- magnetometry
- application
- manufacturing process
- radical nitroxide
- nitroxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- -1 RADICAL NITROXIDE Chemical class 0.000 title 1
- 238000005404 magnetometry Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/20—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations containing free radicals, e.g. trityl radical for overhauser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/653—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/6533—Six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8815107A FR2639350B1 (fr) | 1988-11-21 | 1988-11-21 | Radical nitroxyde, son procede de fabrication et son application en magnetometrie |
GB8924622A GB2225015B (en) | 1988-11-21 | 1989-11-01 | Nitroxide radical,its production process and its use in magnetometry |
US07/433,597 US5006663A (en) | 1988-11-21 | 1989-11-08 | Phosphorus-containing cyclic nitroxide free radicals |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8815107A FR2639350B1 (fr) | 1988-11-21 | 1988-11-21 | Radical nitroxyde, son procede de fabrication et son application en magnetometrie |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2639350A1 FR2639350A1 (fr) | 1990-05-25 |
FR2639350B1 true FR2639350B1 (fr) | 1990-12-21 |
Family
ID=9372036
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8815107A Expired - Lifetime FR2639350B1 (fr) | 1988-11-21 | 1988-11-21 | Radical nitroxyde, son procede de fabrication et son application en magnetometrie |
Country Status (3)
Country | Link |
---|---|
US (1) | US5006663A (fr) |
FR (1) | FR2639350B1 (fr) |
GB (1) | GB2225015B (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2688594B1 (fr) * | 1992-03-13 | 1994-04-29 | Commissariat Energie Atomique | Materiau organique utilisable dans un magnetometre et sonde pour magnetometre a resonance paramagnetique electronique (rpe) utilisant ce materiau. |
US5264204A (en) * | 1992-04-30 | 1993-11-23 | Mallinckrodt Medical, Inc. | Hydrophilic free radicals for magnetic resonance imaging |
FR2707990B1 (fr) * | 1993-07-20 | 1995-10-20 | Centre Nat Rech Scient | Nouvelles nitrones utilisables pour le piégeage des radicaux libres. |
AU8051894A (en) * | 1993-10-25 | 1995-05-22 | Oklahoma Medical Research Foundation | Novel phosphorus-containing spin-trap compositions |
US5622687A (en) * | 1994-11-15 | 1997-04-22 | Molecular Biosystems, Inc. | Calixarene conjugates useful as MRI and CT diagnostic imaging agents |
FR2730240A1 (fr) | 1995-02-07 | 1996-08-09 | Atochem Elf Sa | Stabilisation d'un polymere par un radical libre stable |
FR2776293B1 (fr) * | 1998-03-18 | 2002-10-04 | Centre Nat Rech Scient | Nouveaux aminophosphonates et utilisation d'aminophosphonates comme marqueurs de ph et rmn du 31p |
EP1089734A2 (fr) * | 1998-06-26 | 2001-04-11 | Georgetown University Medical Center | Compositions et procedes d'induction de la mort de cellules |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4920974B1 (fr) * | 1970-06-01 | 1974-05-29 | ||
GB1325775A (en) * | 1970-06-10 | 1973-08-08 | Ciba Geigy Uk Ltd | Phosphorus-containing piperidine derivatives and their use as stabilisers for polymerica material |
CA1001232A (en) * | 1973-11-30 | 1976-12-07 | Ivan Hrvoic | Nuclear dynamic polarization magnetometer |
US4105432A (en) * | 1977-07-18 | 1978-08-08 | Monsanto Company | Cyclized derivatives of N-(2-hydroxyalkyl)-N-phosphonomethylglycine compounds |
FR2546518B1 (fr) * | 1980-10-09 | 1986-08-01 | Commissariat Energie Atomique | Radicaux nitroxydes et leur procede de fabrication, application a la magnetometrie et a la gyrometrie |
-
1988
- 1988-11-21 FR FR8815107A patent/FR2639350B1/fr not_active Expired - Lifetime
-
1989
- 1989-11-01 GB GB8924622A patent/GB2225015B/en not_active Expired - Lifetime
- 1989-11-08 US US07/433,597 patent/US5006663A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
GB8924622D0 (en) | 1989-12-20 |
GB2225015B (en) | 1992-07-15 |
GB2225015A (en) | 1990-05-23 |
FR2639350A1 (fr) | 1990-05-25 |
US5006663A (en) | 1991-04-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CL | Concession to grant licences | ||
ST | Notification of lapse |