FR2630916B1 - Compositions pharmaceutiques de polypeptides adaptees a la resorption gastro-intestinale - Google Patents

Compositions pharmaceutiques de polypeptides adaptees a la resorption gastro-intestinale

Info

Publication number
FR2630916B1
FR2630916B1 FR8907995A FR8907995A FR2630916B1 FR 2630916 B1 FR2630916 B1 FR 2630916B1 FR 8907995 A FR8907995 A FR 8907995A FR 8907995 A FR8907995 A FR 8907995A FR 2630916 B1 FR2630916 B1 FR 2630916B1
Authority
FR
France
Prior art keywords
pharmaceutical compositions
polypeptides
resorption
gastrointestinal
gastrointestinal resorption
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8907995A
Other languages
English (en)
Other versions
FR2630916A1 (fr
Inventor
Vonderscher Jacky
Franz Joachim
Steiger Michel
Hornung Karl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH2138/86A external-priority patent/CH667994A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2630916A1 publication Critical patent/FR2630916A1/fr
Application granted granted Critical
Publication of FR2630916B1 publication Critical patent/FR2630916B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
FR8907995A 1986-05-27 1989-06-14 Compositions pharmaceutiques de polypeptides adaptees a la resorption gastro-intestinale Expired - Fee Related FR2630916B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH214486 1986-05-27
CH2138/86A CH667994A5 (de) 1986-05-27 1986-05-27 Pharmazeutische zusammensetzungen mit polypeptid-wirkstoffen.

Publications (2)

Publication Number Publication Date
FR2630916A1 FR2630916A1 (fr) 1989-11-10
FR2630916B1 true FR2630916B1 (fr) 1993-10-22

Family

ID=25689611

Family Applications (2)

Application Number Title Priority Date Filing Date
FR878707368A Expired FR2599254B1 (fr) 1986-05-27 1987-05-25 Compositions pharmaceutiques de polypeptides adaptees a la resorption gastro-intestinale.
FR8907995A Expired - Fee Related FR2630916B1 (fr) 1986-05-27 1989-06-14 Compositions pharmaceutiques de polypeptides adaptees a la resorption gastro-intestinale

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR878707368A Expired FR2599254B1 (fr) 1986-05-27 1987-05-25 Compositions pharmaceutiques de polypeptides adaptees a la resorption gastro-intestinale.

Country Status (21)

Country Link
US (1) US5393738A (fr)
KR (1) KR870010870A (fr)
AU (1) AU601740B2 (fr)
BE (1) BE1000722A4 (fr)
CA (1) CA1299495C (fr)
DE (1) DE3716437A1 (fr)
DK (1) DK265587A (fr)
ES (1) ES2008126A6 (fr)
FI (1) FI872313A (fr)
FR (2) FR2599254B1 (fr)
GB (1) GB2190838B (fr)
GR (1) GR870820B (fr)
HU (1) HU198626B (fr)
IL (1) IL82645A0 (fr)
LU (1) LU86901A1 (fr)
MY (1) MY101233A (fr)
NL (1) NL8701143A (fr)
NO (1) NO171484C (fr)
NZ (1) NZ220418A (fr)
SE (1) SE8702188L (fr)
WO (1) WO1987007149A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3822557C2 (de) * 1987-07-10 1998-07-02 Ciba Geigy Ag Arzneimittel, enthaltend Somatostatine
FR2668933B1 (fr) * 1990-06-15 1995-05-05 Sandoz Sa Composition pharmaceutique a base de somatostatine.
GB9013448D0 (en) * 1990-06-15 1990-08-08 Sandoz Ltd Pharmaceutical resorption-improved somatostatin compositions,their preparation and use
US5571788A (en) * 1991-12-09 1996-11-05 Ciba-Geigy Corporation Stable calcitonin pharmaceutical compositions
DE19949897A1 (de) * 1999-10-15 2001-04-19 Rainer Rogasch Formkörper und Verfahren zu dessen Herstellung
EP1118333A1 (fr) * 2000-01-18 2001-07-25 Eurand International S.P.A. Compositions avec une biodisponibilité orale augmentée
ES2383303T3 (es) 2005-11-10 2012-06-20 Chemi S.P.A. Formulaciones de inhibidores de la liberación prolongada de la hormona del crecimiento análogos de la somatostatina
ES2629131T3 (es) 2008-09-17 2017-08-07 Chiasma Inc. Composiciones farmacéuticas y métodos de suministro relacionados.
AU2015201581B2 (en) * 2008-09-17 2017-03-09 Amryt Endo, Inc. Pharmaceutical Compositions and Related Methods of Delivery
CA2784120A1 (fr) 2009-12-16 2011-07-14 Nod Pharmaceuticals, Inc. Compositions et procedes d'administration de medicaments par voie orale
US20110142889A1 (en) * 2009-12-16 2011-06-16 Nod Pharmaceuticals, Inc. Compositions and methods for oral drug delivery
US20110182985A1 (en) * 2010-01-28 2011-07-28 Coughlan David C Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof
EP3229824A4 (fr) 2014-12-10 2018-07-11 Chiasma Inc. Octréotide destiné à être administré par voie orale en association avec d'autres agents thérapeutiques
US10265384B2 (en) 2015-01-29 2019-04-23 Novo Nordisk A/S Tablets comprising GLP-1 agonist and enteric coating
MA41462A (fr) 2015-02-03 2021-05-12 Chiasma Inc Méthode de traitement de maladies
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1062898A (en) * 1912-12-09 1913-05-27 Fred Drew Automobile.
GB1062898A (en) * 1963-06-14 1967-03-22 Evans Medical Ltd Pharmaceutical compositions containing protamines
CA959759A (en) * 1970-01-15 1974-12-24 John J. Miskel Method for absorption of drugs
NL167323C (nl) * 1970-09-26 1981-12-16 Organon Nv Werkwijze ter bereiding van een psychofarmacologisch preparaat.
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4041155A (en) * 1974-10-29 1977-08-09 American Home Products Corporation Long acting somatostatin composition
US4151276A (en) * 1975-05-12 1979-04-24 Armour Pharmaceutical Company Method of suppressing gastric acid secretion by the oral administration of calcitonin
CA1098444A (fr) * 1975-05-26 1981-03-31 Leo Geller Preparations de peptide a action prolongee
NL7607987A (nl) * 1975-08-08 1977-02-10 Merck & Co Inc Werkwijze voor het bereiden van peptiden.
SE7612534L (sv) * 1975-12-01 1977-06-02 Henkel & Cie Gmbh Forfarande for framstellning av farmaceutiska preparat for behandling av storningar i kalciumemnesomsettning
US4093574A (en) * 1977-02-02 1978-06-06 Eli Lilly And Company Somatostatin analogs and intermediates thereto
US4087390A (en) * 1977-02-02 1978-05-02 Eli Lilly And Company Somatostatin analogs and intermediates thereto
DK144731C (da) * 1976-07-30 1982-10-18 Nordisk Insulinlab Fremgangsmaade til isolering af proteinhormoner stammende fra humant hypofysevaev
US4230695A (en) * 1976-08-02 1980-10-28 Vitose Corporation Enhanced protein assimilation with fructose
JPS5920647B2 (ja) * 1976-10-01 1984-05-15 武田薬品工業株式会社 注射剤
US4162248A (en) * 1976-10-14 1979-07-24 Merck & Co., Inc. Somatostatin analogs
GB2008403B (en) * 1977-11-04 1982-07-28 Christie R B Parsons J A Pharmaceutical compositions
CA1107273A (fr) * 1978-05-19 1981-08-18 Chester A. Meyers Analogues de la somatostatine ayant un residu tryptophyl substitue en position 8
EP0029579B1 (fr) * 1979-11-27 1983-02-16 Sandoz Ag Polypeptides, procédés pour leur préparation, compositions pharmaceutiques les contenant et leur utilisation
JPS56122309A (en) * 1980-03-03 1981-09-25 Teijin Ltd Calcitonin pharmaceutical for rectal administration
JPS57146722A (en) * 1981-03-06 1982-09-10 Toyo Jozo Co Ltd Pharmaceutical preparation having improved absorption
JPS57146723A (en) * 1981-03-06 1982-09-10 Toyo Jozo Co Ltd Pharmaceutical preparation having improved absorption
JPS57118509A (en) * 1981-01-14 1982-07-23 Toyo Jozo Co Ltd Novel preparation of high absorbability
US4900730A (en) * 1981-01-14 1990-02-13 Toyo Jozo Co., Ltd. Preparation which promotes the absorption of peptides
SE460638B (sv) * 1981-01-14 1989-11-06 Toyo Jozo Kk Suppositoriepreparat med foerbaettrad absorptionsegenskap
JPS5885813A (ja) * 1981-11-17 1983-05-23 Toyo Jozo Co Ltd 吸収性良好な製剤
JPS57128634A (en) * 1981-02-03 1982-08-10 Eisai Co Ltd Elastase-containing compound increasing absorption
WO1982003773A1 (fr) * 1981-04-27 1982-11-11 Baxter Travenol Lab Solution de dialyse contenant du glucose, des acides amines et de l'insuline
EP0083619A1 (fr) * 1981-07-17 1983-07-20 Nordisk Insulinlaboratorium Preparation therapeutique d'insuline aqueuse stable et son procede de preparation
US4457916A (en) * 1982-08-31 1984-07-03 Asahi Kasei Kogyo Kabushiki Kaisha Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same
GB2127689B (en) * 1982-10-05 1986-07-09 Sandoz Ltd Calcitonin inhalation compositions
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
WO1985002118A1 (fr) * 1983-11-21 1985-05-23 Regents Of The University Of Minnesota Melange tamponne de polyol-hormone destine a etre utilise dans l'administration parenterale chronique d'hormones
JPS6197229A (ja) * 1984-10-18 1986-05-15 Chugai Pharmaceut Co Ltd 安定なエリトロポエチン製剤
JPS61267528A (ja) * 1984-11-26 1986-11-27 Yamanouchi Pharmaceut Co Ltd 吸収促進剤を含有するカルシトニン経鼻剤
US4650787A (en) * 1985-04-25 1987-03-17 Schally Andrew Victor Biologically active octapeptides

Also Published As

Publication number Publication date
FI872313A (fi) 1987-11-28
DK265587D0 (da) 1987-05-25
SE8702188D0 (sv) 1987-05-25
ES2008126A6 (es) 1989-07-16
AU7336487A (en) 1987-12-03
NO171484C (no) 1993-03-24
GB8712193D0 (en) 1987-06-24
NO171484B (no) 1992-12-14
HU198626B (en) 1989-11-28
LU86901A1 (fr) 1987-12-16
KR870010870A (ko) 1987-12-18
GB2190838A (en) 1987-12-02
NO872174D0 (no) 1987-05-25
CA1299495C (fr) 1992-04-28
US5393738A (en) 1995-02-28
FR2599254B1 (fr) 1989-12-01
HUT43956A (en) 1988-01-28
MY101233A (en) 1991-08-17
FI872313A0 (fi) 1987-05-25
WO1987007149A1 (fr) 1987-12-03
GR870820B (en) 1987-09-25
DK265587A (da) 1987-11-28
SE8702188L (sv) 1987-11-28
AU601740B2 (en) 1990-09-20
FR2630916A1 (fr) 1989-11-10
NL8701143A (nl) 1987-12-16
FR2599254A1 (fr) 1987-12-04
BE1000722A4 (fr) 1989-03-21
IL82645A0 (en) 1987-11-30
GB2190838B (en) 1990-12-12
NZ220418A (en) 1990-07-26
DE3716437A1 (de) 1987-12-03
NO872174L (no) 1987-11-30

Similar Documents

Publication Publication Date Title
KR880011653U (ko) 의약용 캅셀
DK89090D0 (da) Farmaceutisk praeparat
DK195988A (da) Farmaceutisk praeparat indeholdende mikrokapsler
SE8801813L (sv) Pharmaceutical composition
KR890701101A (ko) 제약학적 조성물
FR2630916B1 (fr) Compositions pharmaceutiques de polypeptides adaptees a la resorption gastro-intestinale
DK100488D0 (da) Farmaceutisk plaster
DK256488A (da) Immunmodulerende farmaceutisk praeparat
DK705488D0 (da) Farmaceutisk praeparat
ATA327387A (de) Pharmazeutisches ranitidinpraeparat
MC1878A1 (fr) Compositions pharmaceutiques
IT1221493B (it) Composizioni farmaceutiche a cessione ritardata
MX172943B (es) Formulacion farmaceutica
DK139388D0 (da) Farmaceutisk praeparat
MX11584A (es) Composiciones farmaceuticas
IT1216814B (it) Composizioni farmaceutiche
DK624587D0 (da) Farmaceutisk praeparat indeholdende imidazolderivater
IT1222142B (it) Composizioni farmaceutiche antivirali
IT1203737B (it) Composizioni farmaceutiche comprendenti 3-amminopropossi-indoli
DK138888A (da) Farmaceutisk praeparat
IT1202567B (it) Preparazione di amoxicillina iniettabile farmaceutica
DK428287D0 (da) Nasalt farmaceutisk praeparat
FR2608597B1 (fr) Compositions pharmaceutiques contenant de l'acetylsalicylate de lysine
SE8602975D0 (sv) Farmaceutisk beredning
SE8603912D0 (sv) Farmaceutisk beredning

Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse