FR2622578B1 - Nouveaux derives de l'acide aminopimelique, leur procede de preparation et leur application comme medicaments - Google Patents
Nouveaux derives de l'acide aminopimelique, leur procede de preparation et leur application comme medicamentsInfo
- Publication number
- FR2622578B1 FR2622578B1 FR8715209A FR8715209A FR2622578B1 FR 2622578 B1 FR2622578 B1 FR 2622578B1 FR 8715209 A FR8715209 A FR 8715209A FR 8715209 A FR8715209 A FR 8715209A FR 2622578 B1 FR2622578 B1 FR 2622578B1
- Authority
- FR
- France
- Prior art keywords
- denotes
- hydrogen atom
- radical
- compounds
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title abstract 2
- JUQLUIFNNFIIKC-UHFFFAOYSA-N 2-aminopimelic acid Chemical class OC(=O)C(N)CCCCC(O)=O JUQLUIFNNFIIKC-UHFFFAOYSA-N 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 235000001014 amino acid Nutrition 0.000 abstract 2
- 150000001413 amino acids Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 substituted alkyl radical Chemical class 0.000 abstract 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 235000004279 alanine Nutrition 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000002483 medication Methods 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000003140 primary amides Chemical class 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000003334 secondary amides Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Virology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Priority Applications (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8715209A FR2622578B1 (fr) | 1987-11-03 | 1987-11-03 | Nouveaux derives de l'acide aminopimelique, leur procede de preparation et leur application comme medicaments |
| MX013643A MX173858B (es) | 1987-11-03 | 1988-11-01 | Procedimiento para la preparacion de derivados del acido amino-pimelico y compuestos obtenidos |
| DK607688A DK607688A (da) | 1987-11-03 | 1988-11-01 | Aminopimelinsyrederivater, fremgangsmaade til deres fremstilling samt laegemidler med indhold deraf |
| AT88402741T ATE87299T1 (de) | 1987-11-03 | 1988-11-02 | Aminopimelinsaeure-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel. |
| JP63276337A JPH01151543A (ja) | 1987-11-03 | 1988-11-02 | 新規のアミノピメリン酸誘導体、それらの製造方法及びそれらの薬剤としての使用 |
| ZA888200A ZA888200B (en) | 1987-11-03 | 1988-11-02 | Derivatives of aminopimelic acid,their process of preparation and their application as medicaments |
| CA000581930A CA1310445C (fr) | 1987-11-03 | 1988-11-02 | Derives de l'acide aminopimelique, leur procede de preparation et leurapplication comme medicaments |
| HU885678A HU202471B (en) | 1987-11-03 | 1988-11-02 | Process for producing aminopimelic acid derivatives and pharmaceutical compositions comprising such compounds |
| EP88402741A EP0315519B1 (fr) | 1987-11-03 | 1988-11-02 | Nouveaux dérivés de l'acide aminopimélique, leur procédé de préparation et leur application comme médicaments |
| DE88402741T DE3879622T2 (de) | 1987-11-03 | 1988-11-02 | Aminopimelinsäure-Derivate, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel. |
| ES88402741T ES2053787T3 (es) | 1987-11-03 | 1988-11-02 | Nuevos derivados del acido aminopimelico, su procedimiento de preparacion y su aplicacion como medicamentos. |
| AU24582/88A AU615229B2 (en) | 1987-11-03 | 1988-11-02 | New derivatives of amino pimelic acid, their preparation process and their application as medicaments |
| PT88926A PT88926B (pt) | 1987-11-03 | 1988-11-03 | Processo para a preparacao de derivados do acido aminopimelico e de compostos farmaceuticos que o contem |
| US07/267,190 US5030715A (en) | 1987-11-03 | 1988-11-03 | Novel aminopimelic acids |
| GR920402861T GR3007597T3 (https=) | 1987-11-03 | 1993-04-09 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8715209A FR2622578B1 (fr) | 1987-11-03 | 1987-11-03 | Nouveaux derives de l'acide aminopimelique, leur procede de preparation et leur application comme medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2622578A1 FR2622578A1 (fr) | 1989-05-05 |
| FR2622578B1 true FR2622578B1 (fr) | 1990-03-16 |
Family
ID=9356421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8715209A Expired - Fee Related FR2622578B1 (fr) | 1987-11-03 | 1987-11-03 | Nouveaux derives de l'acide aminopimelique, leur procede de preparation et leur application comme medicaments |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5030715A (https=) |
| EP (1) | EP0315519B1 (https=) |
| JP (1) | JPH01151543A (https=) |
| AT (1) | ATE87299T1 (https=) |
| AU (1) | AU615229B2 (https=) |
| CA (1) | CA1310445C (https=) |
| DE (1) | DE3879622T2 (https=) |
| DK (1) | DK607688A (https=) |
| ES (1) | ES2053787T3 (https=) |
| FR (1) | FR2622578B1 (https=) |
| GR (1) | GR3007597T3 (https=) |
| HU (1) | HU202471B (https=) |
| MX (1) | MX173858B (https=) |
| PT (1) | PT88926B (https=) |
| ZA (1) | ZA888200B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6077915A (en) * | 1990-07-23 | 2000-06-20 | Exxon Research & Engineering | Carbonyl containing compounds |
| DE60135634D1 (de) * | 2000-01-11 | 2008-10-16 | Molecular Insight Pharm Inc | Polypharmacophore verbindungen |
| CN113072456B (zh) * | 2021-04-12 | 2022-04-19 | 中国科学技术大学 | 一种手性α-二氟甲基氨基酸类化合物及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2566410A1 (fr) * | 1984-06-20 | 1985-12-27 | Delalande Sa | Nouveaux derives de l'acide diaminopimelique, leur procede de preparation et leur application en therapeutique |
-
1987
- 1987-11-03 FR FR8715209A patent/FR2622578B1/fr not_active Expired - Fee Related
-
1988
- 1988-11-01 DK DK607688A patent/DK607688A/da not_active Application Discontinuation
- 1988-11-01 MX MX013643A patent/MX173858B/es unknown
- 1988-11-02 DE DE88402741T patent/DE3879622T2/de not_active Expired - Fee Related
- 1988-11-02 AT AT88402741T patent/ATE87299T1/de not_active IP Right Cessation
- 1988-11-02 EP EP88402741A patent/EP0315519B1/fr not_active Expired - Lifetime
- 1988-11-02 HU HU885678A patent/HU202471B/hu not_active IP Right Cessation
- 1988-11-02 CA CA000581930A patent/CA1310445C/fr not_active Expired - Lifetime
- 1988-11-02 ES ES88402741T patent/ES2053787T3/es not_active Expired - Lifetime
- 1988-11-02 JP JP63276337A patent/JPH01151543A/ja active Pending
- 1988-11-02 AU AU24582/88A patent/AU615229B2/en not_active Ceased
- 1988-11-02 ZA ZA888200A patent/ZA888200B/xx unknown
- 1988-11-03 PT PT88926A patent/PT88926B/pt not_active IP Right Cessation
- 1988-11-03 US US07/267,190 patent/US5030715A/en not_active Expired - Fee Related
-
1993
- 1993-04-09 GR GR920402861T patent/GR3007597T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3879622D1 (de) | 1993-04-29 |
| MX13643A (es) | 1993-09-01 |
| MX173858B (es) | 1994-04-07 |
| ZA888200B (en) | 1990-01-31 |
| AU615229B2 (en) | 1991-09-26 |
| DK607688A (da) | 1989-06-20 |
| FR2622578A1 (fr) | 1989-05-05 |
| PT88926A (pt) | 1988-12-01 |
| ATE87299T1 (de) | 1993-04-15 |
| EP0315519A3 (en) | 1990-02-28 |
| CA1310445C (fr) | 1992-11-17 |
| DE3879622T2 (de) | 1993-09-30 |
| US5030715A (en) | 1991-07-09 |
| GR3007597T3 (https=) | 1993-08-31 |
| DK607688D0 (da) | 1988-11-01 |
| ES2053787T3 (es) | 1994-08-01 |
| EP0315519B1 (fr) | 1993-03-24 |
| AU2458288A (en) | 1989-05-25 |
| HU202471B (en) | 1991-03-28 |
| HUT48568A (en) | 1989-06-28 |
| JPH01151543A (ja) | 1989-06-14 |
| EP0315519A2 (fr) | 1989-05-10 |
| PT88926B (pt) | 1993-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |