FR2586017B1 - Nouveaux composes hemiacetaliques et leurs applications - Google Patents

Nouveaux composes hemiacetaliques et leurs applications

Info

Publication number
FR2586017B1
FR2586017B1 FR8608514A FR8608514A FR2586017B1 FR 2586017 B1 FR2586017 B1 FR 2586017B1 FR 8608514 A FR8608514 A FR 8608514A FR 8608514 A FR8608514 A FR 8608514A FR 2586017 B1 FR2586017 B1 FR 2586017B1
Authority
FR
France
Prior art keywords
novel
applications
hemiacetal compounds
hemiacetal
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8608514A
Other languages
English (en)
Other versions
FR2586017A1 (fr
Inventor
Guy Vanlerberghe
Alexandre Zysman
Henri Sebag
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Publication of FR2586017A1 publication Critical patent/FR2586017A1/fr
Application granted granted Critical
Publication of FR2586017B1 publication Critical patent/FR2586017B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/12—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/10—Saturated ethers of polyhydroxy compounds
    • C07C43/11—Polyethers containing —O—(C—C—O—)n units with ≤ 2 n≤ 10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/13—Saturated ethers containing hydroxy or O-metal groups
    • C07C43/135—Saturated ethers containing hydroxy or O-metal groups having more than one ether bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/04—Seven-membered rings not condensed with other rings
    • C07D321/08—1,4-Dioxepines; Hydrogenated 1,4-dioxepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/812—Liposome comprising an antibody, antibody fragment, antigen, or other specific or nonspecific immunoeffector
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8608514A 1985-06-14 1986-06-12 Nouveaux composes hemiacetaliques et leurs applications Expired FR2586017B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU85952A LU85952A1 (fr) 1985-06-14 1985-06-14 Nouveaux composes hemiacetaliques et leurs applications

Publications (2)

Publication Number Publication Date
FR2586017A1 FR2586017A1 (fr) 1987-02-13
FR2586017B1 true FR2586017B1 (fr) 1988-03-25

Family

ID=19730488

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8608514A Expired FR2586017B1 (fr) 1985-06-14 1986-06-12 Nouveaux composes hemiacetaliques et leurs applications

Country Status (5)

Country Link
US (3) US4827003A (fr)
DE (1) DE3619883A1 (fr)
FR (1) FR2586017B1 (fr)
GB (3) GB2176481B (fr)
LU (1) LU85952A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU85952A1 (fr) * 1985-06-14 1987-01-13 Oreal Nouveaux composes hemiacetaliques et leurs applications
US4976953A (en) * 1987-03-06 1990-12-11 The Procter & Gamble Company Skin conditioning/cleansing compositions containing propoxylated glycerol derivatives
US5290562A (en) * 1987-11-27 1994-03-01 L V M H Recherche Compositions and methods employing liposomes including tyrosine or a tyrosine derivative
FR2623716B1 (fr) * 1987-11-27 1991-04-05 Lvmh Rech Composition a base de phases lamellaires lipidiques hydratees ou de liposomes contenant de la tyrosine ou un derive de tyrosine et composition cosmetique ou pharmaceutique, notamment dermatologique, a activite pigmentante, l'incorporant
US6372249B1 (en) 1991-12-16 2002-04-16 Baylor College Of Medicine Senscent cell-derived inhibitors of DNA synthesis
FR2694289B1 (fr) * 1992-07-29 1994-10-14 Oreal Composés amphiphiles soufrés, fluorés et polyglycérolés, composition cosmétique ou pharmaceutique en comportant, procédé de préparation et vésicules formées.
DE4312656C2 (de) * 1993-04-19 1996-01-25 Beiersdorf Ag Kühlend wirkende kosmetische oder dermatologische Zusammensetzungen
DE69427251T2 (de) * 1993-07-27 2001-10-31 Terumo Corp Verabreichungssystem für Arzneistoffe
WO1996012716A1 (fr) * 1994-10-22 1996-05-02 Chong Kun Dang Corp. Derives nucleosidiques et leur procede de preparation
DE19622224A1 (de) 1996-02-16 1997-08-21 Max Planck Gesellschaft Phosphatidyloligoglycerine
CA2246568C (fr) 1996-02-16 2007-08-07 Hans-Jorg Eibl Phosphatidyloligoglycerines
DE19748796A1 (de) * 1997-11-05 1999-05-06 Beiersdorf Ag Verfahren zur Herstellung von Liposomen
DE19835611A1 (de) 1998-08-06 2000-02-10 Max Planck Gesellschaft Neuartige Phospholipide mit synthetischen, ungesättigten Alkyl- und Acylketten
ES2313037T3 (es) * 2003-06-13 2009-03-01 Dsm Ip Assets B.V. Materiales encapsulados.
US20080031909A1 (en) * 2004-12-10 2008-02-07 Dsm Ip Assets B.V. Encapsulated Cosmetic Materials
US8623344B2 (en) * 2007-06-29 2014-01-07 Mcneil-Ppc, Inc. Structured depilatory compositions
WO2009042839A1 (fr) * 2007-09-28 2009-04-02 Varian Medical Systems, Inc. Liposomes radiosensibles
JP5270188B2 (ja) * 2008-02-22 2013-08-21 株式会社クラレ 新規なアクリル酸エステル誘導体、高分子化合物
CN105218511B (zh) * 2015-10-12 2017-07-14 太原理工大学 一种脂肪醛缩甘油磺基琥珀酸单酯盐及其制备工艺
KR101917854B1 (ko) * 2017-08-24 2018-11-12 한국콜마주식회사 세포 수용체 결합능이 있는 펩티드를 포함하는 마이크로 캡슐 및 이를 포함하는 화장료 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US32084A (en) * 1861-04-16 Improvement in corn-planters
GB443559A (en) * 1934-06-15 1936-02-17 Ig Farbenindustrie Ag Improvements in the manufacture and production of valuable watersoluble condensationproducts suitable as assistants in the textile and related industries
US2418297A (en) * 1944-01-04 1947-04-01 Shell Dev Substituted dioxanes
US3427248A (en) * 1965-10-22 1969-02-11 Lever Brothers Ltd Detergent
GB1270578A (en) * 1968-08-17 1972-04-12 Fuji Photo Film Co Ltd Hardening of gelatin
DE2522287C2 (de) * 1975-05-20 1981-09-24 Degussa Ag, 6000 Frankfurt Mittel zur antistatischen Ausrüstung von thermoplastischen Kunststoffen
FR2315991A1 (fr) 1975-06-30 1977-01-28 Oreal Procede de fabrication de dispersions aqueuses de spherules lipidiques et nouvelles compositions correspondantes
DE2631030A1 (de) * 1976-07-09 1978-01-12 Bayer Ag Kationische farbstoffe
USRE32084E (en) 1976-09-17 1986-02-18 National Distillers And Chemical Corporation Glycol aldehyde and ethylene glycol processes
CA1157774A (fr) * 1980-07-30 1983-11-29 Anthony Cerami Methode pour diminuer la viscosite de la mucine
JPS57197236A (en) * 1981-05-28 1982-12-03 Kao Corp 2-hydroxy-3-methyl branched alkoxypropyl glyceryl ether and cosmetic containing the same
EP0094586A3 (fr) * 1982-05-13 1984-06-06 Ono Pharmaceutical Co., Ltd. Dérivés de glycérol, procédé pour leur préparation et compositions pharmaceutiques les contenant
LU85952A1 (fr) * 1985-06-14 1987-01-13 Oreal Nouveaux composes hemiacetaliques et leurs applications

Also Published As

Publication number Publication date
LU85952A1 (fr) 1987-01-13
GB8614435D0 (en) 1986-07-16
GB2218096A (en) 1989-11-08
GB2218096B (en) 1990-04-04
GB8911935D0 (en) 1989-07-12
US5164488A (en) 1992-11-17
US4827003A (en) 1989-05-02
GB2221683A (en) 1990-02-14
FR2586017A1 (fr) 1987-02-13
US5008406A (en) 1991-04-16
GB2176481B (en) 1989-07-19
GB2176481A (en) 1986-12-31
GB8921736D0 (en) 1989-11-08
DE3619883A1 (de) 1986-12-18

Similar Documents

Publication Publication Date Title
FR2586017B1 (fr) Nouveaux composes hemiacetaliques et leurs applications
FR2532646B1 (fr) Nouveaux composes polymeriques d'ammonium quaternaire et leurs applications
KR870700608A (ko) 아미노-살리실산 유도체 및 제약 조성물
FR2523139B1 (fr) Copolyesters et leurs applications
DK266185D0 (da) Pasteuriseringsapparat
MA20407A1 (fr) Derives de l'hydroxy-4-2h-1-benzothiopyran-2-one,leurs preparations et applications
MA20743A1 (fr) Composes nouveaux
IT1197061B (it) Composizioni farmaceutiche ad azione vasodilatatrice e antianossica
BR8605186A (pt) Artigo foto-sensitivo
FR2576020B1 (fr) 5-halopyridine-3-carboxamides et leurs applications
BE870570R (fr) Nouveaux composes de rifamycine et leurs applications en therapeutique
FR2484425B1 (fr) Polyoxyalkylene-siloxanes speciaux et leurs applications
NO920885L (no) Framstilling av plastprodukter
FR2584702B1 (fr) Nouveaux composes du neodyme, leurs procedes de preparation et leurs applications
IT8520843A0 (it) Difosfoniti cicliche loro preparazione e applicazioni.
FR2592379B1 (fr) Pyridine-3-carboxamides et leurs applications
FR2568883B1 (fr) Interferon bovin et sa preparation
FR2571053B1 (fr) Nouveaux composes d'ammonium quaternaire, leur preparation et applications
FR2564465B1 (fr) Nouveaux diamino-1,3 propanols-2, leurs methodes de preparation et leurs applications therapeutiques
FR2552093B1 (fr) Nouveaux derives de sulfures de polycarbone, leur preparation et leurs applications, notamment en electrochimie
FR2549474B1 (fr) Nouveaux thioamides, leurs preparation et applications
BE891462A (fr) Derives d'acide nicotinique et leurs preparations
FR2564461B1 (fr) Derives d'isoquinoleine, leur preparation et leurs applications
FR2568251B1 (fr) Nouveaux derives d'isoquinoleine et leurs applications therapeutiques
FR2313057A1 (fr) Nouveaux composes de la 4,4-diphenylcyclohexylpiperidine et leurs applications

Legal Events

Date Code Title Description
ST Notification of lapse
ST Notification of lapse