FR2571053B1 - Nouveaux composes d'ammonium quaternaire, leur preparation et applications - Google Patents

Nouveaux composes d'ammonium quaternaire, leur preparation et applications

Info

Publication number
FR2571053B1
FR2571053B1 FR8512700A FR8512700A FR2571053B1 FR 2571053 B1 FR2571053 B1 FR 2571053B1 FR 8512700 A FR8512700 A FR 8512700A FR 8512700 A FR8512700 A FR 8512700A FR 2571053 B1 FR2571053 B1 FR 2571053B1
Authority
FR
France
Prior art keywords
applications
preparation
quaternary ammonium
ammonium compounds
novel quaternary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8512700A
Other languages
English (en)
Other versions
FR2571053A1 (fr
Inventor
Gabriel Amitai
David Balderman
Rachel Bruckstein-Davidov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Israel Institute for Biological Research
Original Assignee
Israel Institute for Biological Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Israel Institute for Biological Research filed Critical Israel Institute for Biological Research
Publication of FR2571053A1 publication Critical patent/FR2571053A1/fr
Application granted granted Critical
Publication of FR2571053B1 publication Critical patent/FR2571053B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20—Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR8512700A 1984-08-28 1985-08-26 Nouveaux composes d'ammonium quaternaire, leur preparation et applications Expired FR2571053B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL72788A IL72788A (en) 1984-08-28 1984-08-28 Bis quaternary oxy-bis methylene(or trimethylene)bis-n-quinuclidines,pyridines and piperidines,their preparation and antidotes against organophosphorus and carbamate poisoning containing them

Publications (2)

Publication Number Publication Date
FR2571053A1 FR2571053A1 (fr) 1986-04-04
FR2571053B1 true FR2571053B1 (fr) 1988-12-02

Family

ID=11055287

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8512700A Expired FR2571053B1 (fr) 1984-08-28 1985-08-26 Nouveaux composes d'ammonium quaternaire, leur preparation et applications

Country Status (3)

Country Link
CA (1) CA1283412C (fr)
FR (1) FR2571053B1 (fr)
IL (1) IL72788A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235878A3 (fr) * 1986-01-16 1989-06-14 Beecham Group Plc Nouveaux composés
DK1345937T3 (da) 2000-12-22 2006-01-16 Almirall Prodesfarma Ag Quinuclidincarbamatderivater og deres anvendelse som M3-antagonister
EE05404B1 (et) * 2000-12-28 2011-04-15 Almirall Prodesfarma Ag Kinuklidiini derivaat, selle saamine ja kasutamine ravimi valmistamiseks, mis on ette n„htud respiratoorsete, kuseelundite v?i mao-soolte haiguste ravimiseks, ning seda sisaldav ravimkompositsioon
ES2204295B1 (es) 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2834779A (en) * 1956-12-11 1958-05-13 Lakeside Lab Inc Disubstituted aminoalkyl quinuclidinium derivatives
US3077476A (en) * 1959-04-28 1963-02-12 Jr Brennie E Hackley Bis quaternary oximes
US3135761A (en) * 1959-04-28 1964-06-02 Jr Brennie E Hackley Bis quaternary oximes
DE1670672A1 (de) * 1966-02-18 1970-12-03 Merck Patent Gmbh Bis-Quartaere Pyridiniumsalze und Verfahren zu ihrer Herstellung
US3919240A (en) * 1966-08-17 1975-11-11 Harold Z Sommer Quaternary quinuclidinones
DE1670208A1 (de) * 1967-04-01 1971-02-25 Albert Scherer Verfahren zur Herstellung von unsymmetrischen Bispyridiniumsalzen der Bishalogenmethylaether
US3852294A (en) * 1968-08-27 1974-12-03 Merck Patent Gmbh Bis-quaternary pyridinium salts
DE2616481A1 (de) * 1976-04-14 1977-11-03 Merck Patent Gmbh Bis-quartaere pyridinium-2-aldoxim- salze und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
IL72788A (en) 1989-07-31
FR2571053A1 (fr) 1986-04-04
IL72788A0 (en) 1984-11-30
CA1283412C (fr) 1991-04-23

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Legal Events

Date Code Title Description
ST Notification of lapse