FR2585709B1 - Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents
Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennentInfo
- Publication number
- FR2585709B1 FR2585709B1 FR8511936A FR8511936A FR2585709B1 FR 2585709 B1 FR2585709 B1 FR 2585709B1 FR 8511936 A FR8511936 A FR 8511936A FR 8511936 A FR8511936 A FR 8511936A FR 2585709 B1 FR2585709 B1 FR 2585709B1
- Authority
- FR
- France
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- cycloamidic
- lactonic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- IVOMOUWHDPKRLL-KQYNXXCUSA-N Cyclic adenosine monophosphate Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=CN=C2N)=C2N=C1 IVOMOUWHDPKRLL-KQYNXXCUSA-N 0.000 abstract 1
- IVOMOUWHDPKRLL-UHFFFAOYSA-N UNPD107823 Natural products O1C2COP(O)(=O)OC2C(O)C1N1C(N=CN=C2N)=C2N=C1 IVOMOUWHDPKRLL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940095074 cyclic amp Drugs 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8511936A FR2585709B1 (fr) | 1985-08-05 | 1985-08-05 | Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| DK364786A DK364786A (da) | 1985-08-05 | 1986-07-31 | Fremgangsmaade til fremstilling af hidtil ukendte peptidderivater, der har en lakton eller cykloamid struktur |
| US06/892,345 US4725581A (en) | 1985-08-05 | 1986-08-01 | New peptide compounds having a lactone or cycloamide structure |
| EP86401738A EP0217688B1 (fr) | 1985-08-05 | 1986-08-04 | Nouveaux dérivés peptidiques à structure lactonique ou cycloamidique, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
| GR862059A GR862059B (en) | 1985-08-05 | 1986-08-04 | Method for preparing peptidic derivatives of a lactonic or cycloamidic structure |
| CA000515267A CA1276397C (fr) | 1985-08-05 | 1986-08-04 | Derives peptidiques a structure lactonique ou cycloamidique et leur procede de preparation |
| AU60812/86A AU581599B2 (en) | 1985-08-05 | 1986-08-04 | New peptide compounds having a lactone or cycloamide structure |
| AT86401738T ATE56976T1 (de) | 1985-08-05 | 1986-08-04 | Peptidderivate mit lactonischer oder zykloamidischer struktur, deren verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen. |
| NZ217079A NZ217079A (en) | 1985-08-05 | 1986-08-04 | Peptide derivatives and pharmaceutical compositions |
| DE8686401738T DE3674525D1 (de) | 1985-08-05 | 1986-08-04 | Peptidderivate mit lactonischer oder zykloamidischer struktur, deren verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen. |
| ES8600846A ES2000128A6 (es) | 1985-08-05 | 1986-08-04 | Procedimiento de preparacion de nuevos derivados peptidicos de estructura lactonica o cicloamidica |
| ZA865826A ZA865826B (en) | 1985-08-05 | 1986-08-04 | Peptide derivatives having a lactone or cycloamide structure,process for the preparation thereof and pharmaceutical compositions containing them |
| JP61184117A JPS6233198A (ja) | 1985-08-05 | 1986-08-05 | 新規なペプチド誘導体 |
| PT83145A PT83145B (pt) | 1985-08-05 | 1986-08-05 | Processo para a preparacao de novos derivados peptidicos com estrutura lactonica ou cicloamidica |
| IE208586A IE58541B1 (en) | 1985-08-05 | 1986-08-05 | Novel peptide derivatives having a lactone or cycloamide structure, process for the preparation thereof, and pharmaceutical compositions containing them |
| JP64000815A JPH01230597A (ja) | 1985-08-05 | 1989-01-05 | 新規なペプチド誘導体 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8511936A FR2585709B1 (fr) | 1985-08-05 | 1985-08-05 | Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2585709A1 FR2585709A1 (fr) | 1987-02-06 |
| FR2585709B1 true FR2585709B1 (fr) | 1987-10-02 |
Family
ID=9321967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8511936A Expired FR2585709B1 (fr) | 1985-08-05 | 1985-08-05 | Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4725581A (enExample) |
| EP (1) | EP0217688B1 (enExample) |
| JP (2) | JPS6233198A (enExample) |
| AT (1) | ATE56976T1 (enExample) |
| AU (1) | AU581599B2 (enExample) |
| CA (1) | CA1276397C (enExample) |
| DE (1) | DE3674525D1 (enExample) |
| DK (1) | DK364786A (enExample) |
| ES (1) | ES2000128A6 (enExample) |
| FR (1) | FR2585709B1 (enExample) |
| GR (1) | GR862059B (enExample) |
| IE (1) | IE58541B1 (enExample) |
| NZ (1) | NZ217079A (enExample) |
| PT (1) | PT83145B (enExample) |
| ZA (1) | ZA865826B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0696575B2 (ja) * | 1987-09-17 | 1994-11-30 | 三菱化成株式会社 | ４−アミノピリジン誘導体及びその酸付加塩 |
| GB2227658A (en) * | 1989-02-03 | 1990-08-08 | Cellana | Thyrotropin releasing hormone (trh) composition for enhancing immune function |
| FR2649110B1 (fr) * | 1989-06-29 | 1994-10-21 | Adir | Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2663336B1 (fr) * | 1990-06-18 | 1992-09-04 | Adir | Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5504071A (en) * | 1990-10-03 | 1996-04-02 | Polifarma S.P.A. | Compounds with a sequence of three radicals, the central one being α-a |
| IT1242002B (it) * | 1990-10-03 | 1994-02-02 | Polifarma Spa | Composti con attivita' farmacologica antiipertensiva, analgesica, immunomodulante e antiinfiammatoria, che presentano nella molecola una sequenza di tre radicali, essendo alfa-amminoacido quello centrale |
| FR2694295B1 (fr) * | 1992-07-28 | 1994-09-02 | Adir | Nouveaux peptides dérivés de trifluoromethylcetones, leur procéde de préparation et les compositions pharmaceutiques qui les contiennent. |
| AU1757597A (en) * | 1996-02-05 | 1997-08-22 | Eli Lilly And Company | Method of treating beta-amyloid peptide associated conditions using trh |
| DE19616509A1 (de) * | 1996-04-25 | 1998-01-15 | Asta Medica Ag | Neue spezifische Immunophilin-Liganden als Antiasthmatika, Immunsuppressiva |
| BR0308118A (pt) * | 2002-03-01 | 2005-01-11 | Warner Lambert Co | Método para o tratamento de osteoartrite |
| US7628342B2 (en) | 2004-05-11 | 2009-12-08 | Daiwa Can Company | Liquefied gas dispensing nozzle and liquefied gas dispensing apparatus |
| WO2007089616A2 (en) | 2006-01-26 | 2007-08-09 | The University Of Rochester | Inhibiting amyloid-beta peptide/rage interaction at the blood-brain barrier |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5944308B2 (ja) * | 1976-03-23 | 1984-10-29 | 武田薬品工業株式会社 | ペプタイド |
| US4260601A (en) * | 1979-10-23 | 1981-04-07 | Nyegaard & Co. A/S | Chemical compounds |
| US4293481A (en) * | 1980-07-24 | 1981-10-06 | E. R. Squibb & Sons, Inc. | Tripeptide inhibitors of angiotensin-converting enzyme |
| JPS57188526A (en) * | 1981-05-14 | 1982-11-19 | Takeda Chem Ind Ltd | Peptide-containing pharmaceutical preparation |
| US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
| DE3332633A1 (de) * | 1983-09-09 | 1985-04-04 | Luitpold-Werk Chemisch-pharmazeutische Fabrik GmbH & Co, 8000 München | Substituierte carbonsaeurederivate, verfahren zu ihrer herstellung, und arzneimittel |
-
1985
- 1985-08-05 FR FR8511936A patent/FR2585709B1/fr not_active Expired
-
1986
- 1986-07-31 DK DK364786A patent/DK364786A/da not_active Application Discontinuation
- 1986-08-01 US US06/892,345 patent/US4725581A/en not_active Expired - Fee Related
- 1986-08-04 CA CA000515267A patent/CA1276397C/fr not_active Expired - Lifetime
- 1986-08-04 AT AT86401738T patent/ATE56976T1/de not_active IP Right Cessation
- 1986-08-04 GR GR862059A patent/GR862059B/el unknown
- 1986-08-04 EP EP86401738A patent/EP0217688B1/fr not_active Expired - Lifetime
- 1986-08-04 AU AU60812/86A patent/AU581599B2/en not_active Ceased
- 1986-08-04 ES ES8600846A patent/ES2000128A6/es not_active Expired
- 1986-08-04 DE DE8686401738T patent/DE3674525D1/de not_active Expired - Lifetime
- 1986-08-04 ZA ZA865826A patent/ZA865826B/xx unknown
- 1986-08-04 NZ NZ217079A patent/NZ217079A/en unknown
- 1986-08-05 PT PT83145A patent/PT83145B/pt not_active IP Right Cessation
- 1986-08-05 IE IE208586A patent/IE58541B1/en not_active IP Right Cessation
- 1986-08-05 JP JP61184117A patent/JPS6233198A/ja active Granted
-
1989
- 1989-01-05 JP JP64000815A patent/JPH01230597A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| NZ217079A (en) | 1988-05-30 |
| GR862059B (en) | 1986-12-24 |
| EP0217688A1 (fr) | 1987-04-08 |
| EP0217688B1 (fr) | 1990-09-26 |
| JPH0229680B2 (enExample) | 1990-07-02 |
| JPH01230597A (ja) | 1989-09-14 |
| DE3674525D1 (de) | 1990-10-31 |
| DK364786D0 (da) | 1986-07-31 |
| AU6081286A (en) | 1987-02-12 |
| JPS6233198A (ja) | 1987-02-13 |
| ATE56976T1 (de) | 1990-10-15 |
| ZA865826B (en) | 1987-04-29 |
| IE58541B1 (en) | 1993-10-06 |
| AU581599B2 (en) | 1989-02-23 |
| DK364786A (da) | 1987-02-06 |
| PT83145A (fr) | 1986-09-01 |
| JPH0259160B2 (enExample) | 1990-12-11 |
| CA1276397C (fr) | 1990-11-13 |
| US4725581A (en) | 1988-02-16 |
| FR2585709A1 (fr) | 1987-02-06 |
| PT83145B (pt) | 1989-03-30 |
| ES2000128A6 (es) | 1987-12-16 |
| IE862085L (en) | 1987-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse | ||
| R1 | Appeal | ||
| DC | Decision of the supreme court | ||
| ST | Notification of lapse |