FR2582657B1 - Procede de preparation de sels d'heparine - Google Patents

Procede de preparation de sels d'heparine

Info

Publication number
FR2582657B1
FR2582657B1 FR868607875A FR8607875A FR2582657B1 FR 2582657 B1 FR2582657 B1 FR 2582657B1 FR 868607875 A FR868607875 A FR 868607875A FR 8607875 A FR8607875 A FR 8607875A FR 2582657 B1 FR2582657 B1 FR 2582657B1
Authority
FR
France
Prior art keywords
preparation
heparin salts
heparin
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR868607875A
Other languages
English (en)
French (fr)
Other versions
FR2582657A1 (fr
Inventor
Gyorgy Kerey
Janos Illes
Bela Stefko
Erzsebet Neszmelyi
Pal Gere
Istvan Zambo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Nyrt
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Nyrt
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt, Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Nyrt
Publication of FR2582657A1 publication Critical patent/FR2582657A1/fr
Application granted granted Critical
Publication of FR2582657B1 publication Critical patent/FR2582657B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR868607875A 1985-06-04 1986-06-02 Procede de preparation de sels d'heparine Expired - Fee Related FR2582657B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852197A HU193769B (en) 1985-06-04 1985-06-04 Sodium-exchanging process for producing pharmaceutically acceptable heparinates applicable even for injections

Publications (2)

Publication Number Publication Date
FR2582657A1 FR2582657A1 (fr) 1986-12-05
FR2582657B1 true FR2582657B1 (fr) 1991-12-13

Family

ID=10958239

Family Applications (1)

Application Number Title Priority Date Filing Date
FR868607875A Expired - Fee Related FR2582657B1 (fr) 1985-06-04 1986-06-02 Procede de preparation de sels d'heparine

Country Status (6)

Country Link
AT (1) AT397250B (it)
BE (1) BE904867A (it)
FR (1) FR2582657B1 (it)
GB (1) GB2176200B (it)
HU (1) HU193769B (it)
IT (1) IT1190124B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8702254D0 (sv) * 1987-05-29 1987-05-29 Kabivitrum Ab Novel heparin derivatives
KR920700232A (ko) * 1988-06-03 1992-02-19 원본미기재 글리코사미노글리칸 염류, 그 제조방법 및 이를 함유하는 제약 조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1013641B (de) * 1956-03-20 1957-08-14 Nordmark Werke Gmbh Verfahren zur Reinigung von Heparin
GB904112A (en) * 1958-12-19 1962-08-22 Roussel Uclaf Improvements in or relating to heparine and derivatives thereof
US2989438A (en) * 1958-12-29 1961-06-20 Roussel Uclaf Process of purifying heparin, and product produced therefrom
US3058884A (en) * 1959-09-14 1962-10-16 Abbott Lab Process for purifying heparin
US3160563A (en) * 1960-05-13 1964-12-08 Ormonoterapia Richter Spa Purification of heaprin
US3342683A (en) * 1964-02-25 1967-09-19 Taiyo Gyogyo Kabushiki Kaisha Heparin from whale tissue and method of preparing same
US3451996A (en) * 1968-02-12 1969-06-24 Thompson Farms Co Method for the preparation of heparin
US3817831A (en) * 1973-01-10 1974-06-18 Wilson Pharm & Chem Corp Process for production of alkali metal salt of heparin
GB2027728B (en) * 1978-08-08 1983-03-30 Choay Sa Physiologically acceptable heparin
IT1141263B (it) * 1980-02-29 1986-10-01 Italfarmaco Spa Metodo per la preparazione di eparinato di calcio

Also Published As

Publication number Publication date
HU193769B (en) 1987-11-30
IT1190124B (it) 1988-02-10
AT397250B (de) 1994-02-25
IT8620676A0 (it) 1986-06-04
GB2176200A (en) 1986-12-17
GB8613593D0 (en) 1986-07-09
BE904867A (fr) 1986-10-01
IT8620676A1 (it) 1987-12-04
GB2176200B (en) 1990-01-24
FR2582657A1 (fr) 1986-12-05
ATA144386A (de) 1993-07-15

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Legal Events

Date Code Title Description
ST Notification of lapse