FR2547813B1 - 3-(3-hydroxybutoxy)-1-butanol et sa preparation - Google Patents

3-(3-hydroxybutoxy)-1-butanol et sa preparation

Info

Publication number
FR2547813B1
FR2547813B1 FR848408571A FR8408571A FR2547813B1 FR 2547813 B1 FR2547813 B1 FR 2547813B1 FR 848408571 A FR848408571 A FR 848408571A FR 8408571 A FR8408571 A FR 8408571A FR 2547813 B1 FR2547813 B1 FR 2547813B1
Authority
FR
France
Prior art keywords
hydroxybutoxy
butanol
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR848408571A
Other languages
English (en)
French (fr)
Other versions
FR2547813A1 (fr
Inventor
Elso Manghisi
Aldo Salimbeni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Luso Farmaco dItalia SpA
Original Assignee
Istituto Luso Farmaco dItalia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Luso Farmaco dItalia SpA filed Critical Istituto Luso Farmaco dItalia SpA
Publication of FR2547813A1 publication Critical patent/FR2547813A1/fr
Application granted granted Critical
Publication of FR2547813B1 publication Critical patent/FR2547813B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/13—Saturated ethers containing hydroxy or O-metal groups
    • C07C43/132—Saturated ethers containing hydroxy or O-metal groups both carbon chains being substituted by hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/164—Unsaturated ethers containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR848408571A 1983-05-30 1984-05-30 3-(3-hydroxybutoxy)-1-butanol et sa preparation Expired FR2547813B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21352/83A IT1164254B (it) 1983-05-30 1983-05-30 3-(3-idrossibutossi)-1-butanolo e suo metodo di preparazione

Publications (2)

Publication Number Publication Date
FR2547813A1 FR2547813A1 (fr) 1984-12-28
FR2547813B1 true FR2547813B1 (fr) 1989-01-27

Family

ID=11180528

Family Applications (1)

Application Number Title Priority Date Filing Date
FR848408571A Expired FR2547813B1 (fr) 1983-05-30 1984-05-30 3-(3-hydroxybutoxy)-1-butanol et sa preparation

Country Status (8)

Country Link
US (1) US4584321A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS604146A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE899790A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3419947A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8507449A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2547813B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2142623B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1164254B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2369074C (en) * 1999-04-01 2012-03-13 Esperion Therapeutics, Inc. Ether compounds, compositions, and uses thereof
WO2002030860A2 (en) 2000-10-11 2002-04-18 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
CN101426763A (zh) 2000-10-11 2009-05-06 埃斯佩里安医疗公司 用于胆固醇治疗和相关应用的硫化物和二硫化物化合物和组合物
US20040122091A1 (en) * 2000-10-11 2004-06-24 Esperion Therapeutics, Inc. Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
IL155215A0 (en) 2000-10-11 2003-11-23 Esperion Therapeutics Inc Ether compounds and compositions for cholesterol management and related uses
US7304093B2 (en) * 2000-10-11 2007-12-04 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
JP2004531459A (ja) 2000-10-11 2004-10-14 エスペリオン セラピューティクス，インコーポレイテッド コレステロールマネージメント用スルホキシドおよびビススルホキシド化合物ならびに組成物および関連する使用
US20040192771A1 (en) * 2001-10-11 2004-09-30 Dasseux Jean-Louis Henri Ether compounds and compositions for cholesterol management and related uses
US20050020694A1 (en) * 2001-10-11 2005-01-27 Dasseux Jean-Louis Henri Sulfide and disulfide compounds and compositions for cholesterol management and related uses
US20040204502A1 (en) * 2001-10-11 2004-10-14 Dasseux Jean-Louis Henri Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
CA2480410A1 (en) * 2002-04-10 2003-10-23 Esperion Therapeutics, Inc. Mimics of acyl coenzyme-a comprising pantolactone and pantothenic acid derivatives, compositions thereof, and methods of cholesterol management and related uses
AU2003299993A1 (en) * 2003-01-23 2004-08-23 Esperion Therapeutics, Inc. Hydroxyl compounds and compositions for cholesterol management and related uses
JP2007525408A (ja) 2003-12-24 2007-09-06 エスペリオン セラピューティクス，インコーポレイテッド コレステロール管理および関連使用のためのケトン化合物および組成物
CN103848726B (zh) * 2012-12-09 2017-09-05 河北凯盛医药科技有限公司 一种高纯度二羟二丁基醚及其制备方法
CN103304383B (zh) * 2013-06-18 2015-04-08 重庆医科大学 保胆健素的新合成方法
CN103319316B (zh) * 2013-06-24 2015-06-10 大连理工大学 一种二羟基二丁醚的绿色制备方法
CN103333057A (zh) * 2013-06-24 2013-10-02 大连理工大学 一种二羟基二丁醚的制备方法
CN104230674A (zh) * 2014-08-28 2014-12-24 成都邦泽生物医药科技有限公司 一种二羟基二丁醚的制备方法
BR112017019358A2 (pt) 2015-03-13 2018-05-08 Esperion Therapeutics Inc combinações e formulações de dose fixa compreendendo etc1002 e ezetimiba e métodos de tratamento ou redução do risco de doença cardiovascular
MA41793A (fr) 2015-03-16 2018-01-23 Esperion Therapeutics Inc Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire
CN112437765A (zh) 2019-06-21 2021-03-02 艾斯柏伦治疗公司 贝派地酸的盐形式及其使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT957008B (it) * 1967-11-09 1973-10-10 Luso Farmaco Inst Processo per la preparazione di eteri simmetrici di glicoli re canti ossidrili primari e secon dari
DE2218935C3 (de) * 1972-04-19 1980-01-31 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von wäßrigen Lösungen von N-Vinylpyrrolidonpolymerisaten

Also Published As

Publication number Publication date
GB8411356D0 (en) 1984-06-06
US4584321A (en) 1986-04-22
JPS6241702B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-09-04
ES532802A0 (es) 1985-10-01
JPS604146A (ja) 1985-01-10
IT8321352A1 (it) 1984-11-30
IT1164254B (it) 1987-04-08
BE899790A (fr) 1984-11-30
GB2142623A (en) 1985-01-23
DE3419947C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-11-26
IT8321352A0 (it) 1983-05-30
DE3419947A1 (de) 1984-12-06
GB2142623B (en) 1987-04-15
FR2547813A1 (fr) 1984-12-28
ES8507449A1 (es) 1985-10-01

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