FR2541287B1 - Preparation stable administrable par voie orale de macrolides antibiotiques et procede pour les stabiliser - Google Patents

Preparation stable administrable par voie orale de macrolides antibiotiques et procede pour les stabiliser

Info

Publication number
FR2541287B1
FR2541287B1 FR8319359A FR8319359A FR2541287B1 FR 2541287 B1 FR2541287 B1 FR 2541287B1 FR 8319359 A FR8319359 A FR 8319359A FR 8319359 A FR8319359 A FR 8319359A FR 2541287 B1 FR2541287 B1 FR 2541287B1
Authority
FR
France
Prior art keywords
stabilizing
same
stable oral
antibiotic macrolides
oral administrative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8319359A
Other languages
English (en)
French (fr)
Other versions
FR2541287A1 (fr
Inventor
Masataka Morishita
Masaru Ono
Yukio Sumita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Publication of FR2541287A1 publication Critical patent/FR2541287A1/fr
Application granted granted Critical
Publication of FR2541287B1 publication Critical patent/FR2541287B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
FR8319359A 1982-12-04 1983-12-02 Preparation stable administrable par voie orale de macrolides antibiotiques et procede pour les stabiliser Expired FR2541287B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57212942A JPS59104326A (ja) 1982-12-04 1982-12-04 マクロライド抗生物質の安定な経口用製剤および安定化法

Publications (2)

Publication Number Publication Date
FR2541287A1 FR2541287A1 (fr) 1984-08-24
FR2541287B1 true FR2541287B1 (fr) 1987-08-07

Family

ID=16630843

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8319359A Expired FR2541287B1 (fr) 1982-12-04 1983-12-02 Preparation stable administrable par voie orale de macrolides antibiotiques et procede pour les stabiliser

Country Status (5)

Country Link
US (1) US4716153A (enExample)
JP (1) JPS59104326A (enExample)
FR (1) FR2541287B1 (enExample)
GB (1) GB2132086B (enExample)
IT (1) IT1169476B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3524572A1 (de) * 1985-07-10 1987-01-15 Thomae Gmbh Dr K Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung
IT1222309B (it) * 1987-07-08 1990-09-05 Menarini Sas Utilizzazione di forme farmaceutiche per uso topico contenenti miocamicina per la terapia delle infezione da germi sensibili alla miocamicina stessa
US4877615A (en) * 1988-09-23 1989-10-31 Microlife Technics, Inc. Antifungal product
IL129547A (en) * 1994-10-26 2001-01-11 Novartis Ag Pharmaceutical compositions comprising a macrolide and an acid
US7205279B2 (en) * 1995-10-25 2007-04-17 Novartis Ag Pharmaceutical compositions
DE4444051A1 (de) * 1994-12-10 1996-06-13 Rhone Poulenc Rorer Gmbh Pharmazeutische, oral anwendbare Zubereitung
AU6381201A (en) * 2000-03-28 2001-10-08 Biochemie Gmbh Granulated particles with masked taste
US6514537B1 (en) 2000-06-02 2003-02-04 Cumberland Swan Holdings, Inc. Magnesium citrate solution
ITMI20021725A1 (it) * 2002-08-01 2002-10-31 Zambon Spa Composizioni farmaceutiche ad attivita' antibiotica.
GB0230034D0 (en) * 2002-12-23 2003-01-29 Biochemie Gmbh Organic compounds
US7803817B2 (en) * 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en) * 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
WO2007120544A2 (en) * 2006-04-12 2007-10-25 Alexander Rayna L Compositions comprising pyruvate alkyl esters and uses thereof
AU2007278986B2 (en) * 2006-07-25 2010-09-16 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion using derivatives of small dicarboxylic acids in combination with PPI
AU2008316830B2 (en) 2007-10-25 2016-03-17 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
US12403095B2 (en) 2008-05-30 2025-09-02 Veloxis Pharmaceuticals, Inc. Stabilized tacrolimus composition
WO2011100975A2 (en) * 2010-02-17 2011-08-25 Lifecycle Pharma A/S Stabilized tacrolimus composition
US8604078B2 (en) * 2011-04-06 2013-12-10 Carlos Picornell Darder Fosfomycin pharmaceutical composition
WO2013148891A1 (en) * 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
WO2025111352A1 (en) * 2023-11-21 2025-05-30 Veterinary Pharmacy Corporation Formulations of penicillin and methods for stabilizing penicillin

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064230A (en) * 1966-04-25 1977-12-20 Schmid Laboratories, Inc. Polyenic macrolide compositions
GB1375986A (en) * 1966-04-25 1974-12-04 Schmid Inc Julius Polyenic macrolide composition
US3891752A (en) * 1966-04-25 1975-06-24 Schmid Lab Polyenic macrolide compositions and methods of use
GB1380741A (en) * 1971-02-05 1975-01-15 Squibb & Sons Inc Antibiotic compositions and their preparation
GB1322306A (en) * 1971-04-15 1973-07-04 Meiji Seika Co Stabilized antibiotic preparation and manufacturing process therefor
JPS531328B2 (enExample) * 1971-12-13 1978-01-18
US4137307A (en) * 1973-11-15 1979-01-30 The Green Cross Corporation Process for preparing haptoglobin aqueous solution using strong anion exchanger
US4102999A (en) * 1975-02-10 1978-07-25 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Process for producing stable macromomycin powder
US4127647A (en) * 1975-04-08 1978-11-28 Meiji Seika Kaisha, Ltd. Process for preparation of stable amorphous macrolide antibiotic solids
GB1550359A (en) * 1975-08-07 1979-08-15 Beecham Group Ltd Antibiotic compositions for oral administration
GB1511852A (en) * 1975-09-11 1978-05-24 Beecham Group Ltd Reconstitutable powders
AU514992B2 (en) * 1976-06-18 1981-03-12 Rockwell International Corporation Flexible tube, axial flow valve
ZA786259B (en) * 1977-11-09 1979-10-31 Procter & Gamble Therapeutic composition
JPS54115389A (en) * 1978-02-27 1979-09-07 Meiji Seika Kaisha Ltd Novel macrolide antibiotic derivative and its preparation
AU529422B2 (en) * 1978-10-20 1983-06-09 Eli Lilly And Company Stable erythromycin solution
ZA795508B (en) * 1978-10-23 1981-05-27 Schering Corp Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them
US4338335A (en) * 1980-02-05 1982-07-06 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
JPS56135418A (en) * 1980-03-27 1981-10-22 Green Cross Corp:The Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human
US4340582A (en) * 1981-01-15 1982-07-20 Abbott Laboratories Erythromycin base tablets

Also Published As

Publication number Publication date
FR2541287A1 (fr) 1984-08-24
GB2132086A (en) 1984-07-04
US4716153A (en) 1987-12-29
GB8331772D0 (en) 1984-01-04
IT1169476B (it) 1987-05-27
IT8323956A0 (it) 1983-11-30
GB2132086B (en) 1986-05-21
JPS59104326A (ja) 1984-06-16
JPS6411007B2 (enExample) 1989-02-23

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Legal Events

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TP Transmission of property