FR2521727A2 - Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ - Google Patents
Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ Download PDFInfo
- Publication number
- FR2521727A2 FR2521727A2 FR8202323A FR8202323A FR2521727A2 FR 2521727 A2 FR2521727 A2 FR 2521727A2 FR 8202323 A FR8202323 A FR 8202323A FR 8202323 A FR8202323 A FR 8202323A FR 2521727 A2 FR2521727 A2 FR 2521727A2
- Authority
- FR
- France
- Prior art keywords
- fiber
- radiation
- face
- axis
- organ
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000000056 organ Anatomy 0.000 title claims abstract description 23
- 239000013307 optical fiber Substances 0.000 claims abstract description 14
- 239000000835 fiber Substances 0.000 claims description 38
- 230000005855 radiation Effects 0.000 claims description 36
- 230000003287 optical effect Effects 0.000 claims description 13
- 230000005540 biological transmission Effects 0.000 claims description 10
- 230000033116 oxidation-reduction process Effects 0.000 claims description 6
- 238000005286 illumination Methods 0.000 claims description 5
- 238000011065 in-situ storage Methods 0.000 claims description 3
- 230000001902 propagating effect Effects 0.000 claims 1
- 238000011477 surgical intervention Methods 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 230000003071 parasitic effect Effects 0.000 description 4
- 238000005259 measurement Methods 0.000 description 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 239000000298 carbocyanine Substances 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 238000007675 cardiac surgery Methods 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 238000005253 cladding Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 238000012625 in-situ measurement Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 1
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 108091008695 photoreceptors Proteins 0.000 description 1
- QWYZFXLSWMXLDM-UHFFFAOYSA-M pinacyanol iodide Chemical compound [I-].C1=CC2=CC=CC=C2N(CC)C1=CC=CC1=CC=C(C=CC=C2)C2=[N+]1CC QWYZFXLSWMXLDM-UHFFFAOYSA-M 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6484—Optical fibres
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Surgery (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Optics & Photonics (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8202323A FR2521727A2 (fr) | 1981-03-25 | 1982-02-12 | Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ |
| DE19823210593 DE3210593A1 (de) | 1981-03-25 | 1982-03-23 | Vorrichtung zum messen des oxido-reduktionszustands eines organs am lebenden objekt |
| US06/362,012 US4449535A (en) | 1981-03-25 | 1982-03-25 | Apparatus for measuring in situ the state of oxidation-reduction of a living organ |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8105948A FR2502783A1 (fr) | 1981-03-25 | 1981-03-25 | Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ |
| FR8202323A FR2521727A2 (fr) | 1981-03-25 | 1982-02-12 | Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2521727A2 true FR2521727A2 (fr) | 1983-08-19 |
| FR2521727B2 FR2521727B2 (ref) | 1984-12-07 |
Family
ID=26222296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8202323A Granted FR2521727A2 (fr) | 1981-03-25 | 1982-02-12 | Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US4449535A (ref) |
| DE (1) | DE3210593A1 (ref) |
| FR (1) | FR2521727A2 (ref) |
Families Citing this family (94)
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| GB8416219D0 (en) * | 1984-06-26 | 1984-08-01 | Antec Systems | Patient monitoring apparatus |
| JPS5940830A (ja) * | 1982-08-31 | 1984-03-06 | 浜松ホトニクス株式会社 | レ−ザ光パルスを用いた癌の診断装置 |
| DE3323365C2 (de) * | 1982-09-04 | 1994-10-20 | Gsf Forschungszentrum Umwelt | Verfahren und Vorrichtung zur Ausleuchtung von Hohlräumen |
| US4553034A (en) * | 1983-12-02 | 1985-11-12 | Westinghouse Electric Corp. | Ion exchange resin intrusion monitor |
| US4622974A (en) * | 1984-03-07 | 1986-11-18 | University Of Tennessee Research Corporation | Apparatus and method for in-vivo measurements of chemical concentrations |
| IT1206462B (it) * | 1984-08-07 | 1989-04-27 | Anic Spa | Fotometro a luce impulsata a lunghezza d'onda multipla per monitoraggio non-invasivo. |
| FR2571604B1 (fr) * | 1984-10-11 | 1989-01-06 | Inst Nat Sante Rech Med | Dispositif pour suivre l'etat d'oxydoreduction d'un organe vivant au cours d'une intervention chirurgicale |
| US4657014A (en) * | 1985-03-11 | 1987-04-14 | Shiley, Inc. | Liquid interface fiberoptic coupler |
| EP0590268B1 (en) * | 1985-03-22 | 1998-07-01 | Massachusetts Institute Of Technology | Fiber Optic Probe System for Spectrally Diagnosing Tissue |
| US5318024A (en) * | 1985-03-22 | 1994-06-07 | Massachusetts Institute Of Technology | Laser endoscope for spectroscopic imaging |
| US4718417A (en) * | 1985-03-22 | 1988-01-12 | Massachusetts Institute Of Technology | Visible fluorescence spectral diagnostic for laser angiosurgery |
| US5125404A (en) * | 1985-03-22 | 1992-06-30 | Massachusetts Institute Of Technology | Apparatus and method for obtaining spectrally resolved spatial images of tissue |
| US4913142A (en) * | 1985-03-22 | 1990-04-03 | Massachusetts Institute Of Technology | Catheter for laser angiosurgery |
| US5104392A (en) * | 1985-03-22 | 1992-04-14 | Massachusetts Institute Of Technology | Laser spectro-optic imaging for diagnosis and treatment of diseased tissue |
| US5199431A (en) * | 1985-03-22 | 1993-04-06 | Massachusetts Institute Of Technology | Optical needle for spectroscopic diagnosis |
| CN85100424B (zh) * | 1985-04-01 | 1986-10-29 | 上海医疗器械研究所 | 恶性肿瘤固有荧光诊断仪 |
| GB2203831B (en) * | 1986-07-07 | 1991-02-06 | Academy Of Applied Sciences | Apparatus and method for the diagnosis of malignant tumours |
| US5190040A (en) * | 1986-12-26 | 1993-03-02 | Nihon Kohden Corporation | Apparatus for measuring the change in the concentration of a pigment in blood |
| US4894547A (en) * | 1987-09-28 | 1990-01-16 | Yale University | Optical method and apparatus for detecting and measuring aging, photoaging, dermal disease and pigmentation in skin |
| US5111821A (en) * | 1988-11-08 | 1992-05-12 | Health Research, Inc. | Fluorometric method for detecting abnormal tissue using dual long-wavelength excitation |
| ATE133545T1 (de) * | 1988-12-21 | 1996-02-15 | Massachusetts Inst Technology | Verfahren für laserinduzierte fluoreszenz von gewebe |
| US5148022A (en) * | 1989-02-15 | 1992-09-15 | Hitachi, Ltd. | Method for optically inspecting human body and apparatus for the same |
| US5048524A (en) * | 1989-03-03 | 1991-09-17 | Camino Laboratories, Inc. | Blood parameter measurement |
| US5201318A (en) * | 1989-04-24 | 1993-04-13 | Rava Richard P | Contour mapping of spectral diagnostics |
| USH1114H (en) | 1990-04-30 | 1992-12-01 | Medtronic, Inc. | Fiber-optic oxygen saturation/hematocrit sensor |
| US5197470A (en) * | 1990-07-16 | 1993-03-30 | Eastman Kodak Company | Near infrared diagnostic method and instrument |
| NL9001660A (nl) * | 1990-07-20 | 1992-02-17 | Laica Laser Technology Venture | Inrichting voor het detecteren van lucht in de pleura-holte en pneumothorax-detector met deze inrichting. |
| US5166756A (en) * | 1990-11-28 | 1992-11-24 | Nir Systems Incorporated | Powder fiber optic probe having angled end in nir optical analyzing instrument |
| DE69231614T2 (de) | 1991-02-26 | 2001-05-03 | Massachusetts Institute Of Technology, Cambridge | Molekularspektroskopieverfahren und -einrichtungen zur gewebediagnose |
| US5280788A (en) * | 1991-02-26 | 1994-01-25 | Massachusetts Institute Of Technology | Devices and methods for optical diagnosis of tissue |
| GB9206948D0 (en) * | 1992-03-31 | 1992-05-13 | Kodak Ltd | Optical fibre sensors |
| US5341805A (en) * | 1993-04-06 | 1994-08-30 | Cedars-Sinai Medical Center | Glucose fluorescence monitor and method |
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| US5541081A (en) * | 1994-03-22 | 1996-07-30 | President And Fellows Of Harvard College | Process for assessing oocyte and embryo quality |
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| US5764840A (en) * | 1995-11-20 | 1998-06-09 | Visionex, Inc. | Optical fiber with enhanced light collection and illumination and having highly controlled emission and acceptance patterns |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3136310A (en) * | 1960-01-18 | 1964-06-09 | Bausch & Lomb | Optical catheter |
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-
1982
- 1982-02-12 FR FR8202323A patent/FR2521727A2/fr active Granted
- 1982-03-23 DE DE19823210593 patent/DE3210593A1/de not_active Withdrawn
- 1982-03-25 US US06/362,012 patent/US4449535A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FR2521727B2 (ref) | 1984-12-07 |
| DE3210593A1 (de) | 1982-10-28 |
| US4449535A (en) | 1984-05-22 |
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| AM | Act modifying the rights related to an application or a patent | ||
| TP | Transmission of property |