FR2463763A1 - Derives de naphtacene, un procede et les intermediaires pour leur preparation - Google Patents

Derives de naphtacene, un procede et les intermediaires pour leur preparation Download PDF

Info

Publication number
FR2463763A1
FR2463763A1 FR8018050A FR8018050A FR2463763A1 FR 2463763 A1 FR2463763 A1 FR 2463763A1 FR 8018050 A FR8018050 A FR 8018050A FR 8018050 A FR8018050 A FR 8018050A FR 2463763 A1 FR2463763 A1 FR 2463763A1
Authority
FR
France
Prior art keywords
group
cis
formula
compound
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8018050A
Other languages
English (en)
French (fr)
Other versions
FR2463763B1 (enExample
Inventor
Cedric Herbert Hassal
Michael John Broadhurst
Gareth John Thomas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2463763A1 publication Critical patent/FR2463763A1/fr
Application granted granted Critical
Publication of FR2463763B1 publication Critical patent/FR2463763B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/567—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with sulfur as the only hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8018050A 1979-08-20 1980-08-18 Derives de naphtacene, un procede et les intermediaires pour leur preparation Granted FR2463763A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7928889 1979-08-20
GB8023715A GB2056443B (en) 1979-08-20 1980-07-21 Cyclic compounds

Publications (2)

Publication Number Publication Date
FR2463763A1 true FR2463763A1 (fr) 1981-02-27
FR2463763B1 FR2463763B1 (enExample) 1984-03-09

Family

ID=26272625

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8018050A Granted FR2463763A1 (fr) 1979-08-20 1980-08-18 Derives de naphtacene, un procede et les intermediaires pour leur preparation

Country Status (8)

Country Link
US (1) US4302398A (enExample)
AT (1) AT367387B (enExample)
CH (1) CH646680A5 (enExample)
DE (1) DE3030612A1 (enExample)
FR (1) FR2463763A1 (enExample)
GB (1) GB2056443B (enExample)
IT (1) IT1132539B (enExample)
NL (1) NL8004716A (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415498A (en) * 1979-11-07 1983-11-15 Research Corporation Synthesis of daunomycinone and the derivatives thereof
US4540695A (en) * 1981-08-12 1985-09-10 Sumitomo Chemical Co., Ltd. Aminonaphthacene derivatives and their use
GB2125030B (en) * 1982-08-13 1986-11-26 Erba Farmitalia Naphthacenequinone synthesis
FR2560876B1 (fr) * 1984-03-09 1987-01-16 Hoechst Lab Nouvelles anthracyclinones, leur procede de preparation, nouveaux glycosides (anthracyclines) obtenus a partir de ces anthracyclinones, utilisation de ces glycosides en tant que medicaments
DE3712350A1 (de) * 1987-04-11 1988-10-20 Behringwerke Ag Semisynthetische rhodomycine, verfahren zu ihrer herstellung und ihre verwendung als zytostatika
DE3822220A1 (de) * 1988-07-01 1990-01-04 Behringwerke Ag Modifizierte rhodomycine, verfahren zu ihrer herstellung und ihre verwendung

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4107423A (en) * 1976-06-14 1978-08-15 Societa Farmaceutici Italia S.P.A. Process for preparing daunomycin and analogues thereof
US4132721A (en) * 1976-06-19 1979-01-02 Societa Farmaceutici Italia S.P.A. Optically active anthracyclinones and process therefor
EP0013577A2 (en) * 1979-01-16 1980-07-23 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Process for the preparation of hexahydronaphthacene derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB877874A (en) * 1959-02-09 1961-09-20 American Cyanamid Co Method of producing polycyclic aromatic boron-containing compounds
US3287270A (en) * 1964-05-05 1966-11-22 Mobil Oil Corp Lubricants and fuels containing boroxarophenanthrene compounds

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4107423A (en) * 1976-06-14 1978-08-15 Societa Farmaceutici Italia S.P.A. Process for preparing daunomycin and analogues thereof
US4132721A (en) * 1976-06-19 1979-01-02 Societa Farmaceutici Italia S.P.A. Optically active anthracyclinones and process therefor
EP0013577A2 (en) * 1979-01-16 1980-07-23 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Process for the preparation of hexahydronaphthacene derivatives

Also Published As

Publication number Publication date
DE3030612C2 (enExample) 1990-06-21
FR2463763B1 (enExample) 1984-03-09
NL8004716A (nl) 1981-02-24
CH646680A5 (de) 1984-12-14
GB2056443A (en) 1981-03-18
IT8024048A0 (it) 1980-08-07
DE3030612A1 (de) 1981-03-12
US4302398A (en) 1981-11-24
GB2056443B (en) 1984-01-18
AT367387B (de) 1982-06-25
ATA422580A (de) 1981-11-15
IT1132539B (it) 1986-07-02

Similar Documents

Publication Publication Date Title
EP2931708B1 (fr) Composes cyclopropylboroniques, leur procede de preparation et leur utilisation
FR2462437A1 (fr) Nouveaux derives de la camptothecine doues d'activite antitumorale et leur procede de preparation
EP2595977A1 (fr) Procede de preparation de derives de benzofurane substitues en position 5
BE1003843A4 (fr) Procede stereospecifique pour la preparation des enantiomeres de la furo (3,4-c) pyridine et composes ainsi obtenus.
MC2028A1 (fr) Procede de preparation de thiazepine-4(5h)-ones optiquement actives,intermediaires de synthese,et procede de preparation de ces intermediaires
EP0334695A1 (fr) Procédé de préparation de dérivés d'isoquinoléine
FR2463763A1 (fr) Derives de naphtacene, un procede et les intermediaires pour leur preparation
FR2587335A1 (fr) Intermediaires intervenant dans la production d'epipodophyllotoxine et composes apparentes : procedes de preparation et emploi
FR2552081A1 (fr) Procede de preparation de prolines substituees
EP0011057B1 (fr) Procédé de synthèse de la vincadifformine et des dérivés apparentés à celle-ci, produits intermédiaires obtenus pendant cette synthèse et procédé pour leur préparation
BE875053A (fr) Composes analogues aux cephalosporines
CH640829A5 (fr) Derives d'hydroquinone et leur procede de synthese.
WO1996038447A1 (fr) Derives du 2-azabicyclo[2.2.1]heptane, leur preparation et leur application
CH638183A5 (fr) Derives de pyrrolidine et de piperidine.
BE1009080A4 (fr) Procede de preparation de l'epibatidine.
EP0419297B1 (fr) Nouveau procédé de séparation d'isomères optiques des dérivés de la dihydro-1,4 pyridine
EP0915867B1 (fr) Derives du thienylcyclohexane pour la synthese de thienylcyclohexyles
BE884828A (fr) Derives de naphtacene
BE563113A (enExample)
EP0828740B1 (fr) Derives du 2-azabicyclo[2.2.1]heptane, leur preparation et leur application
EP1100799B1 (fr) Preparation de derives de la camptothecine et de la nothapodytine
FR2505332A1 (fr) Composes pour la synthese de prostaglandines et prostacyclines contenant de l'azote, et procede pour leur preparation
JPH06172297A (ja) ヒドロキシカルボニル誘導体およびその製造方法
FR2523969A1 (fr) Procede de synthese d'hydroxyethyltetrazolethiols et nouveaux esters alkyliques d'acides n-(hydroxy protege ethyl)dithiocarbamiques et composes de 1-(hydroxy protege ethyl)-1h-tetrazole-5-thiol
FR2477139A1 (fr) Procede de preparation de tetrahydronaphtacenes, derives obtenus et intermediaires de preparation

Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse