FR2452494A1 - 1-epi-fortimicine a et ses derives, utiles notamment comme antibiotiques - Google Patents
1-epi-fortimicine a et ses derives, utiles notamment comme antibiotiquesInfo
- Publication number
- FR2452494A1 FR2452494A1 FR8006885A FR8006885A FR2452494A1 FR 2452494 A1 FR2452494 A1 FR 2452494A1 FR 8006885 A FR8006885 A FR 8006885A FR 8006885 A FR8006885 A FR 8006885A FR 2452494 A1 FR2452494 A1 FR 2452494A1
- Authority
- FR
- France
- Prior art keywords
- lower alkyl
- aminoacyl
- hydrogen atom
- hydroxy
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003242 anti bacterial agent Substances 0.000 title abstract 2
- 229940088710 antibiotic agent Drugs 0.000 title abstract 2
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical group [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 abstract 4
- -1 HYDROXY GROUP Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical class [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 2
- 229930195503 Fortimicin Natural products 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000266 alpha-aminoacyl group Chemical group 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 238000007918 intramuscular administration Methods 0.000 abstract 1
- 238000007912 intraperitoneal administration Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000007920 subcutaneous administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/025,211 US4218442A (en) | 1979-03-29 | 1979-03-29 | 1-Epi-fortimicin A and derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2452494A1 true FR2452494A1 (fr) | 1980-10-24 |
| FR2452494B1 FR2452494B1 (enExample) | 1983-04-22 |
Family
ID=21824686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8006885A Granted FR2452494A1 (fr) | 1979-03-29 | 1980-03-27 | 1-epi-fortimicine a et ses derives, utiles notamment comme antibiotiques |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4218442A (enExample) |
| JP (1) | JPS55130968A (enExample) |
| AR (1) | AR228253A1 (enExample) |
| AU (1) | AU5628280A (enExample) |
| BE (1) | BE882507A (enExample) |
| CA (1) | CA1149813A (enExample) |
| DE (1) | DE3012132A1 (enExample) |
| ES (1) | ES8104318A1 (enExample) |
| FR (1) | FR2452494A1 (enExample) |
| GB (1) | GB2047240B (enExample) |
| GR (1) | GR67745B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4340727A (en) * | 1979-09-26 | 1982-07-20 | Abbott Laboratories | 1,2-Modified fortimicins A and B, intermediates therefor and method for their manufacture |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5850235B2 (ja) * | 1974-12-11 | 1983-11-09 | 明治製菓株式会社 | ３′，４′−α−エポキシ−リボスタマイシン又は−カナマイシンＢの製造法 |
| US4091032A (en) * | 1976-09-23 | 1978-05-23 | Abbott Laboratories | 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A |
| US4124756A (en) * | 1976-12-27 | 1978-11-07 | Abbott Laboratories | 3-DE-O-Methylfortimicins |
| JPS5831603B2 (ja) * | 1977-02-02 | 1983-07-07 | 株式会社東芝 | 分散形ｄｄｃシステムにおける故障バツクアツプ装置 |
| JPS53127401A (en) * | 1977-03-24 | 1978-11-07 | Kowa Co | Novel antibiotics and process for preparing same |
-
1979
- 1979-03-29 US US06/025,211 patent/US4218442A/en not_active Expired - Lifetime
-
1980
- 1980-03-03 CA CA000346821A patent/CA1149813A/en not_active Expired
- 1980-03-07 AU AU56282/80A patent/AU5628280A/en not_active Abandoned
- 1980-03-11 GB GB8008096A patent/GB2047240B/en not_active Expired
- 1980-03-27 ES ES490010A patent/ES8104318A1/es not_active Expired
- 1980-03-27 FR FR8006885A patent/FR2452494A1/fr active Granted
- 1980-03-27 GR GR61538A patent/GR67745B/el unknown
- 1980-03-28 DE DE19803012132 patent/DE3012132A1/de not_active Withdrawn
- 1980-03-28 JP JP3914880A patent/JPS55130968A/ja active Pending
- 1980-03-28 AR AR280484A patent/AR228253A1/es active
- 1980-03-28 BE BE0/200013A patent/BE882507A/fr not_active IP Right Cessation
Non-Patent Citations (1)
| Title |
|---|
| EXBK/77 * |
Also Published As
| Publication number | Publication date |
|---|---|
| GR67745B (enExample) | 1981-09-16 |
| GB2047240A (en) | 1980-11-26 |
| JPS55130968A (en) | 1980-10-11 |
| AU5628280A (en) | 1980-10-02 |
| DE3012132A1 (de) | 1980-10-09 |
| GB2047240B (en) | 1983-07-20 |
| BE882507A (fr) | 1980-09-29 |
| FR2452494B1 (enExample) | 1983-04-22 |
| ES490010A0 (es) | 1981-04-16 |
| CA1149813A (en) | 1983-07-12 |
| US4218442A (en) | 1980-08-19 |
| AR228253A1 (es) | 1983-02-15 |
| ES8104318A1 (es) | 1981-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |