FR2444078A1 - Procede et dispositif pour eprouver l'activite carcinogene ou mutagene de substances - Google Patents

Procede et dispositif pour eprouver l'activite carcinogene ou mutagene de substances

Info

Publication number
FR2444078A1
FR2444078A1 FR7917670A FR7917670A FR2444078A1 FR 2444078 A1 FR2444078 A1 FR 2444078A1 FR 7917670 A FR7917670 A FR 7917670A FR 7917670 A FR7917670 A FR 7917670A FR 2444078 A1 FR2444078 A1 FR 2444078A1
Authority
FR
France
Prior art keywords
carcinogenic
mutagenic activity
test
substances
testing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR7917670A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioresearch Inc
Original Assignee
Bioresearch Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch Inc filed Critical Bioresearch Inc
Publication of FR2444078A1 publication Critical patent/FR2444078A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/807—Gas detection apparatus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Epreuve de l'activité carcinogène ou mutagène potentielle d'une substance. On cultive en 20, en présence d'oxygène, un organisme d'épreuve dans un milieu de croissance ou sa forme mutante peut subir une réversion en la forme normale en présence de la matière active à éprouver, et la réversion est décelée par mesure des différences de consommation d'oxygène à l'aide d'une électrode à oxygène 22 adjacente au milieu de culture 20. Epreuve plus rapide, avec un appareil plus simple, que dans le cas de methodes antérieurement connues.
FR7917670A 1978-12-12 1979-07-06 Procede et dispositif pour eprouver l'activite carcinogene ou mutagene de substances Pending FR2444078A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/968,695 US4256832A (en) 1978-12-12 1978-12-12 Carcinogen and mutagen screening method and apparatus

Publications (1)

Publication Number Publication Date
FR2444078A1 true FR2444078A1 (fr) 1980-07-11

Family

ID=25514635

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7917670A Pending FR2444078A1 (fr) 1978-12-12 1979-07-06 Procede et dispositif pour eprouver l'activite carcinogene ou mutagene de substances

Country Status (6)

Country Link
US (1) US4256832A (fr)
JP (1) JPS5581594A (fr)
AU (1) AU4531679A (fr)
DE (1) DE2949729A1 (fr)
FR (1) FR2444078A1 (fr)
GB (1) GB2045926A (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2535342A1 (fr) * 1982-11-02 1984-05-04 Maillet Jeanne Extrait de mycobacterie en tant que nouveau moyen de detection d'activites cancerigenes et procede mettant en oeuvre ce moyen
EP0258899A2 (fr) * 1986-09-05 1988-03-09 Medical Research Council Test de criblage de l'activité mutagène dans les cellules mammifères
EP0281298A2 (fr) * 1987-02-24 1988-09-07 Mobil Oil Corporation Essai de composés aromatiques polynucléaires
WO1992001064A1 (fr) * 1990-07-05 1992-01-23 Comissariat A L'energie Atomique Procede microbiologique de detection de produits toxiques mineraux ou organiques utilisant des souches de levures du genre saccharomyces

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4442203A (en) * 1981-06-30 1984-04-10 Massachusetts Institute Of Technology Gene amplification assay for detecting tumor promoters
FI67404C (fi) * 1982-07-12 1986-07-28 Labsystems Oy Foerfarande foer utfoering av mutagenitettest
US4871661A (en) * 1983-11-23 1989-10-03 The Ohio State University Research Foundation Process for testing the carcinogenicity of a material or the presence of cancer-inducing factors in an environment
US4499187A (en) * 1984-01-30 1985-02-12 Mobil Oil Corporation Method for evaluating mutagenicity
US5169755A (en) * 1986-12-30 1992-12-08 E. I. Du Pont De Nemours And Company Process for inducing cytochrome P-450 enzymes in streptomyces bacteria and determining the mutagenicity of chemicals
US4822474A (en) * 1987-04-30 1989-04-18 Pennwalt Corporation Residual analyzer assembly
US4997757A (en) * 1987-12-23 1991-03-05 Genebiomed, Inc. Process for detecting potential carcinogens
AUPP438598A0 (en) 1998-06-29 1998-07-23 Garvan Institute Of Medical Research NPY-Y7 receptor gene
US20040107986A1 (en) * 2002-12-06 2004-06-10 Neilson Andy C. High throughput microcalorimeter systems and methods
WO2004065618A2 (fr) * 2003-01-16 2004-08-05 Thermogenic Imaging Procedes et dispositifs permettant de controler le metabolisme cellulaire dans des chambres de retenue de cellules
US7276351B2 (en) 2003-09-10 2007-10-02 Seahorse Bioscience Method and device for measuring multiple physiological properties of cells
US8658349B2 (en) * 2006-07-13 2014-02-25 Seahorse Bioscience Cell analysis apparatus and method
US20070087401A1 (en) * 2003-10-17 2007-04-19 Andy Neilson Analysis of metabolic activity in cells using extracellular flux rate measurements
US8202702B2 (en) * 2008-10-14 2012-06-19 Seahorse Bioscience Method and device for measuring extracellular acidification and oxygen consumption rate with higher precision
JP2013230145A (ja) * 2012-04-30 2013-11-14 Masahiko Sato 細胞集団の状態を評価するための方法、候補化合物の発癌性を評価するための方法、潜在的な抗癌化合物の抗癌活性を評価するための方法及び治療用細胞集団の品質を評価するための方法
WO2014078379A2 (fr) 2012-11-13 2014-05-22 Seahorse Bioscience Appareil et procédés pour des mesures de tissu tridimensionnel sur la base d'un écoulement de milieu contrôlé
US10118177B2 (en) 2014-06-02 2018-11-06 Seahorse Bioscience Single column microplate system and carrier for analysis of biological samples

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3765841A (en) * 1971-08-06 1973-10-16 Beckman Instruments Inc Method and apparatus for chemical analysis
US4038143A (en) * 1973-10-29 1977-07-26 The Regents Of The University Of Michigan Test kit for the genetic detection of microorganisms
US4066510A (en) * 1976-05-24 1978-01-03 Massachusetts Institute Of Technology Assay for mutagenesis in diploid human lymphoblasts
US4072574A (en) * 1976-07-30 1978-02-07 The Institute For Cancer Research System for in vitro assay for mutagenicity and/or carcinogenicity of chemicals or other exogenous agents
GB1579344A (en) 1976-10-25 1980-11-19 British Petroleum Co Microbiological method for estimating the toxicity of industrial effluents

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2535342A1 (fr) * 1982-11-02 1984-05-04 Maillet Jeanne Extrait de mycobacterie en tant que nouveau moyen de detection d'activites cancerigenes et procede mettant en oeuvre ce moyen
EP0258899A2 (fr) * 1986-09-05 1988-03-09 Medical Research Council Test de criblage de l'activité mutagène dans les cellules mammifères
EP0258899A3 (fr) * 1986-09-05 1990-10-10 Medical Research Council Test de criblage de l'activité mutagène dans les cellules mammifères
EP0281298A2 (fr) * 1987-02-24 1988-09-07 Mobil Oil Corporation Essai de composés aromatiques polynucléaires
EP0281298A3 (fr) * 1987-02-24 1989-02-22 Mobil Oil Corporation Essai de composés aromatiques polynucléaires
WO1992001064A1 (fr) * 1990-07-05 1992-01-23 Comissariat A L'energie Atomique Procede microbiologique de detection de produits toxiques mineraux ou organiques utilisant des souches de levures du genre saccharomyces

Also Published As

Publication number Publication date
DE2949729A1 (de) 1980-07-10
JPS5581594A (en) 1980-06-19
AU4531679A (en) 1980-06-19
GB2045926A (en) 1980-11-05
US4256832A (en) 1981-03-17

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