ES8602141A1 - Un metodo de medir un ligando biologico - Google Patents

Un metodo de medir un ligando biologico

Info

Publication number
ES8602141A1
ES8602141A1 ES537707A ES537707A ES8602141A1 ES 8602141 A1 ES8602141 A1 ES 8602141A1 ES 537707 A ES537707 A ES 537707A ES 537707 A ES537707 A ES 537707A ES 8602141 A1 ES8602141 A1 ES 8602141A1
Authority
ES
Spain
Prior art keywords
ligand
combination
enzyme
macromolecular substance
determining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537707A
Other languages
English (en)
Other versions
ES537707A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Inc
Original Assignee
Fujirebio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP21714583A external-priority patent/JPH0245152B2/ja
Priority claimed from JP23124183A external-priority patent/JPS60123767A/ja
Application filed by Fujirebio Inc filed Critical Fujirebio Inc
Publication of ES8602141A1 publication Critical patent/ES8602141A1/es
Publication of ES537707A0 publication Critical patent/ES537707A0/es
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/963—Methods of stopping an enzyme reaction or stabilizing the test materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

METODO DE MEDIDA DE LIGANDOS BIOLOGICOS. CONSISTE EN EMPLEAR UN ANTICUERPO CONTRA UN LIGANDO A QUE HA DE MEDIRSE Y QUE POSEE UNO O MAS DETERMINANTES ANTIGENICOS, UNA ENZIMA CAPAZ DE ACTUAR SOBRE UNA SUSTANCIA MACROMOLECULAR INSOLUBLE EN AGUA Y QUE SE FIJA A DICHO ANTICUERPO O A UN LIGANDO B QUE POSEE AL MENOS EN DETERMINANTE ANTIGENICO COMUN CON EL LIGANDO A, PONER EN CONTACTO EL ANTICUERPO CON EL (LOS) LIGANDO (S) Y PONER EN CONTACTO LA ENZIMA CON LA SUSTANCIA MACROMOLECULAR. DESPUES DE ACABADA LA REACCION SE DETERMINA LA ACTIVIDAD ENZIMATICA. DE APLICACION PARA CUANTIFICAR COMPONENTES TRAZA EN SANGRE CON EL FIN DE FACILITAR EL DIAGNOSTICO DE DIVERSAS ENFERMEDADES.
ES537707A 1983-11-18 1984-11-16 Un metodo de medir un ligando biologico Granted ES537707A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21714583A JPH0245152B2 (ja) 1983-11-18 1983-11-18 Kosoomochiitakogenketsuteikigujubutsushitsunosokuteihoho
JP23124183A JPS60123767A (ja) 1983-12-09 1983-12-09 酵素を用いた抗原決定基具有物質測定法

Publications (2)

Publication Number Publication Date
ES8602141A1 true ES8602141A1 (es) 1985-11-16
ES537707A0 ES537707A0 (es) 1985-11-16

Family

ID=26521843

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537707A Granted ES537707A0 (es) 1983-11-18 1984-11-16 Un metodo de medir un ligando biologico

Country Status (4)

Country Link
US (1) US4692404A (es)
EP (1) EP0144176B1 (es)
DE (1) DE3485339D1 (es)
ES (1) ES537707A0 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757001A (en) * 1984-02-16 1988-07-12 Fujirebio Kabushiki Kaisha Method of measuring biological ligand by utilizing amylase
DE3887314T2 (de) * 1987-07-24 1994-05-11 Nippon Kayaku Kk Methode zum nachweis basischer fötaler proteine im urin und dafür geeigneter analysesatz.
US5179000A (en) * 1987-07-24 1993-01-12 Nippon Kayaku Kabushiki Kaisha Method for assaying basic fetoprotein in urine and assay kit therefor
EP0310940B1 (en) * 1987-09-30 1994-11-23 Fujirebio Kabushiki Kaisha Analytical element for enzyme immunoassays
WO1993011146A1 (en) * 1991-12-06 1993-06-10 University Of Miami Method and ring-opened purine compounds for labeling polynucleotides
DE4217474A1 (de) * 1992-05-27 1993-12-02 Boehringer Mannheim Gmbh Verfahren und Mittel zur Bestimmung eines Analyts
US5447846A (en) * 1992-07-17 1995-09-05 Fuji Photo Film C., Ltd. Homogeneous Immunoassay process using covalent conjugate of enzyme and plural monoclonal antibodies for different epitopes on analyte
US5721112A (en) * 1995-09-14 1998-02-24 Infectech, Inc. Method of determining the presence or absence of a nonparaffinophilic microoganism in a specimen and an associated apparatus
JP2000214165A (ja) * 1999-01-22 2000-08-04 Fuji Photo Film Co Ltd 均一系酵素免疫分析方法
CN101184780B (zh) 2005-05-05 2012-10-03 森馨香料公司 β-葡聚糖和甘露聚糖的制备
JP5492158B2 (ja) 2011-08-24 2014-05-14 富士フイルム株式会社 ヒトｔｓｈ及び犬ｔｓｈに対する抗体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935074A (en) * 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US4268663A (en) * 1979-04-10 1981-05-19 Syva Company Macromolecular glycosidase substrates
US4323647A (en) * 1980-10-15 1982-04-06 University Of Miami Steric hindrance enzyme immunoassay
JPS58122459A (ja) * 1982-01-14 1983-07-21 Yatoron:Kk 酵素の会合を利用した測定方法
IL67289A (en) * 1982-03-18 1985-12-31 Miles Lab Homogeneous immunoassay with labeled monoclonal anti-analyte
DE3362399D1 (en) * 1982-05-24 1986-04-10 Miles Lab Improved homogeneous binding assay method and reagent system, test kit and test device therefor
DE3483620D1 (de) * 1983-03-11 1991-01-03 Fujirebio Kk Verfahren zur bestimmung von liganden.

Also Published As

Publication number Publication date
EP0144176A2 (en) 1985-06-12
EP0144176B1 (en) 1991-12-11
DE3485339D1 (de) 1992-01-23
ES537707A0 (es) 1985-11-16
US4692404A (en) 1987-09-08
EP0144176A3 (en) 1988-08-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050723