FR2442837A1 - Hexahydro-2,6-methano-3-benzazocines, leur preparation et leur utilisation therapeutique - Google Patents

Hexahydro-2,6-methano-3-benzazocines, leur preparation et leur utilisation therapeutique

Info

Publication number
FR2442837A1
FR2442837A1 FR7929171A FR7929171A FR2442837A1 FR 2442837 A1 FR2442837 A1 FR 2442837A1 FR 7929171 A FR7929171 A FR 7929171A FR 7929171 A FR7929171 A FR 7929171A FR 2442837 A1 FR2442837 A1 FR 2442837A1
Authority
FR
France
Prior art keywords
methano
hexahydro
benzazocins
preparation
therapeutic use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7929171A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of FR2442837A1 publication Critical patent/FR2442837A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

L'invention concerne des 3-R1 -7-R2 "-8-R2 -9-R2 '-10-R2 "'- 11 (ax)-R 3 -6 (eq) - R4 -11 (eq)-(CH2 CH2 CH2 R 5 ) -1,2,3,4,5,6-hexahydro-2,6-méthano-3-benzazocines de formule :
FR7929171A 1978-11-30 1979-11-27 Hexahydro-2,6-methano-3-benzazocines, leur preparation et leur utilisation therapeutique Withdrawn FR2442837A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/964,915 US4208523A (en) 1978-11-30 1978-11-30 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines

Publications (1)

Publication Number Publication Date
FR2442837A1 true FR2442837A1 (fr) 1980-06-27

Family

ID=25509154

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7929171A Withdrawn FR2442837A1 (fr) 1978-11-30 1979-11-27 Hexahydro-2,6-methano-3-benzazocines, leur preparation et leur utilisation therapeutique

Country Status (12)

Country Link
US (1) US4208523A (fr)
JP (1) JPS5585569A (fr)
AU (1) AU5303979A (fr)
BE (1) BE880288A (fr)
DE (1) DE2948308A1 (fr)
DK (1) DK507579A (fr)
FR (1) FR2442837A1 (fr)
GB (1) GB2036022B (fr)
IT (1) IT1126432B (fr)
NL (1) NL7908594A (fr)
NZ (1) NZ192189A (fr)
SE (1) SE7909870L (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4912114A (en) * 1988-03-18 1990-03-27 Sandoz Ltd. Morphinan derivatives
DE19740110A1 (de) 1997-09-12 1999-03-18 Boehringer Ingelheim Pharma Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US6375279B1 (en) 1999-02-02 2002-04-23 Kelsey-Hayes Company Hydraulic control unit with fluid compensator to accommodate travel of master cylinder piston

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2034487A1 (fr) * 1969-01-23 1970-12-11 Merck & Co Inc
US3932422A (en) * 1974-05-20 1976-01-13 Sterling Drug Inc. 8-Methylene-3-azabicyclo[3.3.1]non-6-en-4-ones
AT356657B (de) * 1978-03-15 1980-05-12 Sterling Drug Inc Verfahren zur herstellung von 2,6-methano-3- -benzazocinen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1925296A1 (de) * 1969-05-17 1970-11-19 Bayer Ag Benzomorphanderivate
IE34235B1 (en) * 1969-06-04 1975-03-19 Acf Chemiefarma Nv 6,7-benzomorphans and their preparation
US4020164A (en) * 1972-06-30 1977-04-26 Schering Aktiengesellschaft Benzomorphan derivatives
CA1010031A (en) * 1972-10-31 1977-05-10 Kentaro Tamaki 6,7-benzomorphan derivatives
SU510999A3 (ru) * 1973-10-27 1976-04-15 К.Х.Берингер Зон, (Фирма) Способ получени (метоксиметил-фурилметил)6,7-бензоморфанов илиморфинанов
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2034487A1 (fr) * 1969-01-23 1970-12-11 Merck & Co Inc
US3932422A (en) * 1974-05-20 1976-01-13 Sterling Drug Inc. 8-Methylene-3-azabicyclo[3.3.1]non-6-en-4-ones
AT356657B (de) * 1978-03-15 1980-05-12 Sterling Drug Inc Verfahren zur herstellung von 2,6-methano-3- -benzazocinen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/63 *

Also Published As

Publication number Publication date
NL7908594A (nl) 1980-06-03
DE2948308A1 (de) 1980-06-19
GB2036022B (en) 1982-12-01
JPS5585569A (en) 1980-06-27
BE880288A (fr) 1980-05-28
DK507579A (da) 1980-05-31
SE7909870L (sv) 1980-05-31
AU5303979A (en) 1980-06-05
NZ192189A (en) 1981-07-13
IT1126432B (it) 1986-05-21
GB2036022A (en) 1980-06-25
IT7927720A0 (it) 1979-11-29
US4208523A (en) 1980-06-17

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