FR2442234A2 - Derives de phenyl-1 piperazine et leur application en therapeutique - Google Patents

Derives de phenyl-1 piperazine et leur application en therapeutique

Info

Publication number
FR2442234A2
FR2442234A2 FR7833105A FR7833105A FR2442234A2 FR 2442234 A2 FR2442234 A2 FR 2442234A2 FR 7833105 A FR7833105 A FR 7833105A FR 7833105 A FR7833105 A FR 7833105A FR 2442234 A2 FR2442234 A2 FR 2442234A2
Authority
FR
France
Prior art keywords
alkyl
useful
cpds
analgesics
cns
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7833105A
Other languages
English (en)
Other versions
FR2442234B2 (fr
Inventor
Henry Najer
Philippe Michel Jacque Manoury
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7822672A external-priority patent/FR2432515A1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7833105A priority Critical patent/FR2442234A2/fr
Priority to FR7916029A priority patent/FR2459797A2/fr
Priority to DE19792930440 priority patent/DE2930440A1/de
Priority to IT24749/79A priority patent/IT1123497B/it
Priority to AU49309/79A priority patent/AU4930979A/en
Priority to NL7905810A priority patent/NL7905810A/nl
Priority to GB7926224A priority patent/GB2027703A/en
Priority to US06/061,245 priority patent/US4267328A/en
Priority to NZ191140A priority patent/NZ191140A/xx
Priority to DK321479A priority patent/DK321479A/da
Priority to NO792502A priority patent/NO792502L/no
Priority to LU81562A priority patent/LU81562A1/fr
Priority to IL57920A priority patent/IL57920A0/xx
Priority to ES483003A priority patent/ES483003A1/es
Priority to BE0/196538A priority patent/BE877994A/fr
Priority to SE7906507A priority patent/SE7906507L/xx
Priority to JP9858679A priority patent/JPS5522690A/ja
Priority to PT70007A priority patent/PT70007A/fr
Priority to FI792401A priority patent/FI792401A/fi
Publication of FR2442234A2 publication Critical patent/FR2442234A2/fr
Priority to GR59710A priority patent/GR69703B/el
Publication of FR2442234B2 publication Critical patent/FR2442234B2/fr
Application granted granted Critical
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Abstract

Dérivés de phényl-1 pipérazine répondant à la formule générale :
FR7833105A 1978-08-01 1978-11-23 Derives de phenyl-1 piperazine et leur application en therapeutique Granted FR2442234A2 (fr)

Priority Applications (20)

Application Number Priority Date Filing Date Title
FR7833105A FR2442234A2 (fr) 1978-08-01 1978-11-23 Derives de phenyl-1 piperazine et leur application en therapeutique
FR7916029A FR2459797A2 (fr) 1978-08-01 1979-06-22 Derives de phenyl-1 piperazine et leur application en therapeutique
DE19792930440 DE2930440A1 (de) 1978-08-01 1979-07-26 1-phenyl-piperazinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
IT24749/79A IT1123497B (it) 1978-08-01 1979-07-27 Derivati di fenil-1 piperazina
AU49309/79A AU4930979A (en) 1978-08-01 1979-07-27 1-phenylpiperazine derivatives
NL7905810A NL7905810A (nl) 1978-08-01 1979-07-27 Werkwijze voor het bereiden van farmaceutisch preparaat op basis van een piperazinederivaat, dat actief is ten aanzien van het centrale zenuwstelsel en een pijnstil- lend middel is, werkwijze ter bereiding van het piperazinederivaat en het aldus bereide farmaceutische preparaat.
GB7926224A GB2027703A (en) 1978-08-01 1979-07-27 1-Phenylpiperazine derivatives
US06/061,245 US4267328A (en) 1978-08-01 1979-07-27 1-Phenylpiperazines
NZ191140A NZ191140A (en) 1978-08-01 1979-07-27 1-phenylpiperazine derivatives pharmaceutical compositions
NO792502A NO792502L (no) 1978-08-01 1979-07-30 Fremgangsmaate for fremstilling av fenylpiperazinderivater
DK321479A DK321479A (da) 1978-08-01 1979-07-30 Fremgangsmaade til fremstilling af 1-phenylpiperazinderivater
LU81562A LU81562A1 (fr) 1978-08-01 1979-07-30 Derives de phenyl-1 piperazine
IL57920A IL57920A0 (en) 1978-08-01 1979-07-30 1-phenylpiperazine derivatives,their preparation and pharmaceutical compositions containing them
JP9858679A JPS5522690A (en) 1978-08-01 1979-07-31 11phenylpiperazine derivative and its manufacture
BE0/196538A BE877994A (fr) 1978-08-01 1979-07-31 Derives de phenyl-1 piperazine
SE7906507A SE7906507L (sv) 1978-08-01 1979-07-31 Fenyl-1-piperazinderivat
ES483003A ES483003A1 (es) 1978-08-01 1979-07-31 Procedimiento de preparacion de derivados de fenil-1-pipera-zina
PT70007A PT70007A (fr) 1978-08-01 1979-07-31 Procede de preparation de derives de phenyl-1 piperazine
FI792401A FI792401A (fi) 1978-08-01 1979-08-01 1-fenyl-piperazinderivat
GR59710A GR69703B (fr) 1978-08-01 1980-07-27

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7822672A FR2432515A1 (fr) 1978-08-01 1978-08-01 Derives de phenyl-1 piperazine et leur application en therapeutique
FR7833105A FR2442234A2 (fr) 1978-08-01 1978-11-23 Derives de phenyl-1 piperazine et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2442234A2 true FR2442234A2 (fr) 1980-06-20
FR2442234B2 FR2442234B2 (fr) 1981-06-12

Family

ID=26220708

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7833105A Granted FR2442234A2 (fr) 1978-08-01 1978-11-23 Derives de phenyl-1 piperazine et leur application en therapeutique

Country Status (1)

Country Link
FR (1) FR2442234A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2179491A1 (fr) * 1972-04-10 1973-11-23 Synthelabo
FR2224464A1 (en) * 1973-04-05 1974-10-31 Synthelabo N-Phenyl-N'-beta-hydroxy-ethyl piperazines - as analgesic and anti-inflammatory agents
FR2258840A1 (en) * 1974-01-29 1975-08-22 Synthelabo (4-Phenylpiperazino) alkyl esters - with analgesic activity for human and veterinary use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2179491A1 (fr) * 1972-04-10 1973-11-23 Synthelabo
FR2224464A1 (en) * 1973-04-05 1974-10-31 Synthelabo N-Phenyl-N'-beta-hydroxy-ethyl piperazines - as analgesic and anti-inflammatory agents
FR2258840A1 (en) * 1974-01-29 1975-08-22 Synthelabo (4-Phenylpiperazino) alkyl esters - with analgesic activity for human and veterinary use

Also Published As

Publication number Publication date
FR2442234B2 (fr) 1981-06-12

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