FR2420541A1 - Glycoproteine-hgi capable de stimuler la proliferation et la differentiation des granulocytes humains, sa preparation et medicaments de la leucopenie en contenant - Google Patents
Glycoproteine-hgi capable de stimuler la proliferation et la differentiation des granulocytes humains, sa preparation et medicaments de la leucopenie en contenantInfo
- Publication number
- FR2420541A1 FR2420541A1 FR7906887A FR7906887A FR2420541A1 FR 2420541 A1 FR2420541 A1 FR 2420541A1 FR 7906887 A FR7906887 A FR 7906887A FR 7906887 A FR7906887 A FR 7906887A FR 2420541 A1 FR2420541 A1 FR 2420541A1
- Authority
- FR
- France
- Prior art keywords
- reaction
- glycoprotein
- stimulating
- proliferation
- differentiation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000282414 Homo sapiens Species 0.000 title abstract 2
- 230000004069 differentiation Effects 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 210000003714 granulocyte Anatomy 0.000 title abstract 2
- 230000035755 proliferation Effects 0.000 title abstract 2
- 230000004936 stimulating effect Effects 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 201000002364 leukopenia Diseases 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 abstract 6
- 102000003886 Glycoproteins Human genes 0.000 abstract 2
- 108090000288 Glycoproteins Proteins 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- MYKOKMFESWKQRX-UHFFFAOYSA-N 10h-anthracen-9-one;sulfuric acid Chemical compound OS(O)(=O)=O.C1=CC=C2C(=O)C3=CC=CC=C3CC2=C1 MYKOKMFESWKQRX-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 210000001185 bone marrow Anatomy 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 239000010200 folin Substances 0.000 abstract 1
- 230000000788 granulopoietic effect Effects 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- HHIVCXLCMPHUSC-UHFFFAOYSA-N hydron;1h-indol-1-ium;sulfate Chemical compound OS(O)(=O)=O.C1=CC=C2NC=CC2=C1 HHIVCXLCMPHUSC-UHFFFAOYSA-N 0.000 abstract 1
- HFOJRTIFHRRHGA-UHFFFAOYSA-N naphthalen-1-ol;sulfuric acid Chemical compound OS(O)(=O)=O.C1=CC=C2C(O)=CC=CC2=C1 HFOJRTIFHRRHGA-UHFFFAOYSA-N 0.000 abstract 1
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 abstract 1
- 229920001184 polypeptide Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/04—Heat
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP53031999A JPS6030291B2 (ja) | 1978-03-20 | 1978-03-20 | 人顆粒球の分化増殖を促進するｈｇｉ糖蛋白質、ｈｇｉ糖蛋白質の製造法及びｈｇｉ糖蛋白質を含有する白血球減少症治療剤 |
| JP53080695A JPS6030293B2 (ja) | 1978-07-03 | 1978-07-03 | 人顆粒球の分化増殖を促進する加熱処理ｈｇｉｇｐ及びｈｇｉｇｐの加熱処理方法 |
| JP53080694A JPS6030292B2 (ja) | 1978-07-03 | 1978-07-03 | 人顆粒球の分化増殖を促進する加熱処理ｈｇｉｇｐ及びｈｇｉｇｐの加熱処理法 |
| JP53118203A JPS6030294B2 (ja) | 1978-09-26 | 1978-09-26 | 人顆粒球の分化増殖を促進する糖蛋白質を含有する分画の加熱処理方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2420541A1 true FR2420541A1 (fr) | 1979-10-19 |
| FR2420541B1 FR2420541B1 (enrdf_load_stackoverflow) | 1983-05-06 |
Family
ID=27459534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7906887A Granted FR2420541A1 (fr) | 1978-03-20 | 1979-03-19 | Glycoproteine-hgi capable de stimuler la proliferation et la differentiation des granulocytes humains, sa preparation et medicaments de la leucopenie en contenant |
Country Status (8)
| Country | Link |
|---|---|
| AT (1) | AT362392B (enrdf_load_stackoverflow) |
| AU (1) | AU523077B2 (enrdf_load_stackoverflow) |
| CH (1) | CH640865A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2910745A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2420541A1 (enrdf_load_stackoverflow) |
| GB (1) | GB2016477B (enrdf_load_stackoverflow) |
| NL (1) | NL190759C (enrdf_load_stackoverflow) |
| SE (1) | SE451844B (enrdf_load_stackoverflow) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4342828A (en) * | 1979-07-20 | 1982-08-03 | Morinaga Milk Industry Co., Ltd. | Method for producing substance capable of stimulating differentiation and proliferation of human granulopoietic stem cells |
| JPS57144225A (en) * | 1981-03-04 | 1982-09-06 | Tadao Kokubu | Antigenetic preparation for treating nonspecific allergic diseases and its preparation |
| JPH0753667B2 (ja) * | 1985-08-09 | 1995-06-07 | 新技術開発事業団 | 骨髄移植療法補助剤 |
| JPH0618778B2 (ja) * | 1985-10-04 | 1994-03-16 | 中外製薬株式会社 | 白血球減少症治療剤 |
| AU589731B2 (en) * | 1985-11-27 | 1989-10-19 | Genetics Institute, Llc | Colony stimulating factor for the treatment of aids-type diseases |
| GR871067B (en) * | 1986-07-18 | 1987-11-19 | Chugai Pharmaceutical Co Ltd | Process for producing stable pharmaceutical preparation containing granulocyte colony stimulating factor |
-
1979
- 1979-03-16 SE SE7902372A patent/SE451844B/sv not_active IP Right Cessation
- 1979-03-16 AU AU45197/79A patent/AU523077B2/en not_active Expired
- 1979-03-19 GB GB7909494A patent/GB2016477B/en not_active Expired
- 1979-03-19 DE DE19792910745 patent/DE2910745A1/de active Granted
- 1979-03-19 FR FR7906887A patent/FR2420541A1/fr active Granted
- 1979-03-19 CH CH254879A patent/CH640865A5/de not_active IP Right Cessation
- 1979-03-20 NL NL7902178A patent/NL190759C/xx not_active IP Right Cessation
- 1979-03-20 AT AT208479A patent/AT362392B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CH640865A5 (de) | 1984-01-31 |
| DE2910745C2 (enrdf_load_stackoverflow) | 1988-06-23 |
| GB2016477B (en) | 1982-08-25 |
| FR2420541B1 (enrdf_load_stackoverflow) | 1983-05-06 |
| NL190759B (nl) | 1994-03-01 |
| NL190759C (nl) | 1994-08-01 |
| AU523077B2 (en) | 1982-07-08 |
| ATA208479A (de) | 1980-10-15 |
| GB2016477A (en) | 1979-09-26 |
| SE451844B (sv) | 1987-11-02 |
| AT362392B (de) | 1981-05-11 |
| DE2910745A1 (de) | 1979-10-04 |
| AU4519779A (en) | 1979-09-27 |
| SE7902372L (enrdf_load_stackoverflow) | 1979-09-21 |
| NL7902178A (nl) | 1979-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |