FR2417513A1 - Materiau immobilise comportant une proteine biologiquement active liee a un support, sa preparation, et dispositif et procede l'utilisant - Google Patents

Materiau immobilise comportant une proteine biologiquement active liee a un support, sa preparation, et dispositif et procede l'utilisant

Info

Publication number
FR2417513A1
FR2417513A1 FR7904043A FR7904043A FR2417513A1 FR 2417513 A1 FR2417513 A1 FR 2417513A1 FR 7904043 A FR7904043 A FR 7904043A FR 7904043 A FR7904043 A FR 7904043A FR 2417513 A1 FR2417513 A1 FR 2417513A1
Authority
FR
France
Prior art keywords
support
immobilized material
biologically active
preparation
active protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7904043A
Other languages
English (en)
Other versions
FR2417513B1 (fr
Inventor
Kunio Matsumoto
Rokuro Izumi
Hideji Seijo
Hiroyuki Mizuguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Publication of FR2417513A1 publication Critical patent/FR2417513A1/fr
Application granted granted Critical
Publication of FR2417513B1 publication Critical patent/FR2417513B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84—Penicillin amidase (3.5.1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/06—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by desacylation of the substituent in the 6 position

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne un matériau immobilisé consistant en une protéine biologiquement active, comme une enzyme, liée à un support constitue par un polymère de type acrylonitrile contenant des groupements amino. La protéine est liée sur le support, dans un milieu inerte, par absorption physique ou fixation covalente. Un système contenant le maténau immobilisé peut être combiné à un système contenant un substrat sur lequel la protéine est active, pour former un dispositif utilisable dans plusieurs buts. La figure 1 (c) est un exemple d'un tel dispositif, où l'on mesure par l'intermédiaire de l'électrode à oxygène 3 la diminution de l'oxygène dissous, en raison de l'oxydation de l'échantillon B par la choline-oxydase liée à un support 1.
FR7904043A 1978-02-17 1979-02-16 Materiau immobilise comportant une proteine biologiquement active liee a un support, sa preparation, et dispositif et procede l'utilisant Granted FR2417513A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1800178A JPS5548392A (en) 1978-02-17 1978-02-17 Novel immobilizing material combined with biologically active substance, its preparation, device comprising it, method, and preparation of support

Publications (2)

Publication Number Publication Date
FR2417513A1 true FR2417513A1 (fr) 1979-09-14
FR2417513B1 FR2417513B1 (fr) 1983-10-07

Family

ID=11959457

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7904043A Granted FR2417513A1 (fr) 1978-02-17 1979-02-16 Materiau immobilise comportant une proteine biologiquement active liee a un support, sa preparation, et dispositif et procede l'utilisant

Country Status (5)

Country Link
US (2) US4371612A (fr)
JP (1) JPS5548392A (fr)
DE (1) DE2905671C2 (fr)
FR (1) FR2417513A1 (fr)
GB (2) GB2015001B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0216499A2 (fr) * 1985-08-23 1987-04-01 Courtaulds Plc Substrat polymère

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3138194A1 (de) * 1981-09-25 1983-04-14 Basf Ag, 6700 Ludwigshafen Wasserunloesliches poroeses proteinmaterial, dessen herstellung und verwendung
US4511711A (en) * 1982-02-10 1985-04-16 Sumitomo Chemical Company, Limited Process for producing semipermeable membrane
HU187153B (en) * 1982-08-24 1985-11-28 Reanal Finomvegyszergyar Process for producing glucose-aminad enzyme-preparates
US4825693A (en) * 1982-09-30 1989-05-02 Honeywell Inc. Slotted diaphragm semiconductor device
AT383739B (de) * 1983-03-16 1987-08-10 Immuno Ag Verfahren zur inaktivierung von unvertraeglichkeitsreaktionen verursachenden substanzen in immunglobulinhaeltigen blutfraktionen
US5234685A (en) * 1983-03-16 1993-08-10 Immuno Aktiengesellschaft Fur Chemisch-Medizinische Produkte Method of determining incompatibility-reaction-causing substances in blood products as well as a method of inactivating said incompatibility-reaction-causing substances
JPS60118181A (ja) * 1983-11-30 1985-06-25 Kikkoman Corp 食酢の製造法
US4705753A (en) * 1984-06-08 1987-11-10 Gregor Harry P Biologically active acrylonitrile-based copolymeric membrane
US4748121A (en) * 1984-11-30 1988-05-31 Ppg Industries, Inc. Porous glass fibers with immobilized biochemically active material
US5208155A (en) * 1985-01-11 1993-05-04 Klaus Mosbach D-amino acid oxidase and method for isolation thereof
DE3515252C2 (de) * 1985-04-27 1994-02-24 Roehm Gmbh Verfahren zur Immobilisierung gelöster Eiweißstoffe
JPS6322802A (ja) * 1987-03-31 1988-01-30 Toyo Jozo Co Ltd 新規なアミノ化アクリロニトリル系ポリマ−の製造法
US5001048A (en) * 1987-06-05 1991-03-19 Aurthur D. Little, Inc. Electrical biosensor containing a biological receptor immobilized and stabilized in a protein film
US5192507A (en) * 1987-06-05 1993-03-09 Arthur D. Little, Inc. Receptor-based biosensors
WO1989002916A1 (fr) * 1987-09-28 1989-04-06 Novo-Nordisk A/S Procede d'immobilisation de lipase
GB8729889D0 (en) * 1987-12-22 1988-02-03 Unilever Plc Bio-catalysts support systems
US5047437A (en) * 1988-11-23 1991-09-10 American Cyanamid Porous polyacrylonitrile beads and process for their production
DE68921431T2 (de) * 1988-11-23 1995-06-29 Cytec Tech Corp Poröse Oberflächen-hydratisierte Substrate aus Polyacrylnitril, wie Perlderivate, Verfahren zu deren Herstellung und Verfahren zur Verwendung.
US5262317A (en) * 1988-11-23 1993-11-16 E. I. Du Pont De Nemours And Company Polyacrylonitrile modified with hydrogen halide for immobilization of biological substances
US4940734A (en) * 1988-11-23 1990-07-10 American Cyanamid Process for the preparation of porous polymer beads
US5312762A (en) * 1989-03-13 1994-05-17 Guiseppi Elie Anthony Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte
CA2048692A1 (fr) * 1989-03-13 1990-09-14 Anthony Guiseppi-Elie Polymeres conducteurs a groupes fonctionnels groffes en surface et leurs derives, et methode pour leur production
US5418284A (en) * 1989-05-08 1995-05-23 Cytec Technology Corp. Surface-modified polyacrylonitrile beads
JP2888142B2 (ja) 1993-11-08 1999-05-10 三菱電機株式会社 回転電動機並びにその製造方法
US5314816A (en) * 1990-01-08 1994-05-24 Nika Health Products Ltd. Method of preparing lysozyme dimers
US5989880A (en) 1990-01-08 1999-11-23 Nika Health Products Ltd. Method of preparing lysozyme dimers
IT1252308B (it) * 1990-12-21 1995-06-08 Antibioticos Spa Procedimento enzimatico per la produzione di acido 7- amminocefalosporanico e derivati
US5500352A (en) * 1993-03-24 1996-03-19 Sepracor, Inc. Membrane filtration process for 6-aminopenicillanic acid
US6121711A (en) 1993-11-08 2000-09-19 Mitsubishi Denki Kabushiki Kaisha Rotary motor and production method thereof, and laminated core and production method thereof
US5593779A (en) * 1994-06-15 1997-01-14 Kao Corporation Fiber for clothing and production method therefor
DE19600930C1 (de) * 1996-01-12 1997-09-25 Forschungszentrum Juelich Gmbh Neue (bio)chemische Reagenz-Festphasen, Verfahren zu deren Herstellung sowie deren Verwendung
US6248924B1 (en) 1996-06-19 2001-06-19 Basf Aktiengesellschaft Process for reacting an organic compound in the presence of a supported ruthenium catalyst
US5936126A (en) * 1996-06-19 1999-08-10 Basf Aktiengesellschaft Process for reacting an organic compound in the presence of a supported ruthenium catalyst
WO1998015620A1 (fr) * 1996-10-10 1998-04-16 Biotechnology Research And Development Corporation Composites polymeres contenant des proteines, procedes de preparation et utilisation associes
US6291582B1 (en) 1996-10-10 2001-09-18 Biotechnology Research & Development Corp. Polymer-protein composites and methods for their preparation and use
DE19643126A1 (de) * 1996-10-18 1998-04-23 Basf Ag Metall-Festbettkatalysator nach Raney, Verfahren zu seiner Herstellung sowie ein Verfahren zur Hydrierung von Polymeren unter Verwendung dieses Katalysators
US6635269B1 (en) * 1997-11-24 2003-10-21 Morphoplant Gmbh Immobilizing mediator molecules via anchor molecules on metallic implant materials containing oxide layer
DE10037850A1 (de) * 2000-08-01 2002-02-21 Herbert P Jennissen Verfahren zur Herstellung bioaktiver Implantatoberflächen
DE10118554A1 (de) * 2001-04-14 2002-10-24 Henkel Kgaa Enzymabbauketten
WO2002089676A2 (fr) * 2001-05-04 2002-11-14 Concentric Medical Dispositif pour occlusion vasculaire a filament hydrogel
US6927051B1 (en) 2002-04-04 2005-08-09 The University Of Akron Polymer-protein surfactants
WO2003106655A2 (fr) * 2002-06-18 2003-12-24 The University Of Akron Systèmes fibreux d'immobilisation de protéines
US7311926B2 (en) * 2002-12-20 2007-12-25 Battelle Memorial Institute Biocomposite materials and methods for making the same
ATE493157T1 (de) * 2003-09-15 2011-01-15 Smart Tech Lp Implantate mit befestigten silylierten therapeutischen mitteln
CN101151526B (zh) * 2005-03-29 2012-05-30 Cci株式会社 生物传感器
DE102007034726A1 (de) * 2007-07-23 2009-01-29 Henkel Ag & Co. Kgaa Entfernung von Nebenprodukten aus vernetzbaren Zubereitungen
CN103387975A (zh) * 2012-05-11 2013-11-13 上海天伟生物制药有限公司 一种固定化环脂肽酰基转移酶及其制备方法和用途
EP2918609A1 (fr) * 2014-03-10 2015-09-16 LANXESS Deutschland GmbH Compositions vulcanisables contenant du caoutchouc de nitrile hydrogéné contenant des groupes aminométhyle, leur procédé de vulcanisation et vulcanisats ainsi obtenus
EP2918608A1 (fr) * 2014-03-10 2015-09-16 LANXESS Deutschland GmbH Caoutchouc de nitrile hydrogéné contenant des groupes aminométhyle et son procédé de fabrication
EP2918612B1 (fr) * 2014-03-10 2016-09-07 ARLANXEO Deutschland GmbH Caoutchouc de nitrile hydrogéné contenant des groupes aminométhyle, leur procédé de fabrication, compositions vulcanisables contenant du caoutchouc de nitrile hydrogéné contenant des groupes aminométhyle, leur procédé de vulcanisation et vulcanisats ainsi obtenus
WO2019006263A1 (fr) 2017-06-30 2019-01-03 Dow Global Technologies Llc Revêtement pour la réhabilitation d'aldéhyde et procédé de fabrication
SG11202011275XA (en) * 2018-05-15 2020-12-30 Life Science Biosensor Diagnostics Pty Ltd Biosensor with porous wicking layer

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1226303B (de) * 1963-01-24 1966-10-06 Hoechst Ag Verfahren zur Hydrierung von Nitrilgruppen enthaltenden Polymerisaten
FR2074027A5 (fr) * 1969-12-18 1971-10-01 Exploaterings Ab Tbf
FR2084750A5 (fr) * 1970-03-18 1971-12-17 Monsanto Co
FR2228785A1 (fr) * 1973-05-07 1974-12-06 Dorr Oliver Inc
FR2288748A1 (fr) * 1974-08-13 1976-05-21 Beecham Group Ltd Preparation d'enzyme comprenant un enzyme fixe sur des groupes non polaires et application a la preparation d'acide 6-amino-penicillanique

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3788950A (en) * 1970-08-05 1974-01-29 Du Pont Enzyme gel and use therefor
US3830699A (en) * 1972-03-16 1974-08-20 Exxon Research Engineering Co Insolubilized enzymes
US3844892A (en) * 1972-12-19 1974-10-29 Gulf Research Development Co Method of immobilizing enzymes
US3841970A (en) * 1972-12-19 1974-10-15 Gulf Research Development Co Immobilized enzymes
GB1550819A (en) * 1975-06-04 1979-08-22 Nat Res Dev Polymeric support for biogically active materials
JPS527485A (en) * 1975-07-04 1977-01-20 Asahi Chem Ind Co Ltd Isolation of urokinase
JPS5354186A (en) * 1976-10-28 1978-05-17 Asahi Chem Ind Co Ltd Protein adsorbent
JPS5858080B2 (ja) * 1976-11-05 1983-12-23 旭化成株式会社 ７−アミノセフエム化合物の製造法
JPS6032497B2 (ja) * 1976-12-24 1985-07-29 旭化成株式会社 蛋白質吸着用物質

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1226303B (de) * 1963-01-24 1966-10-06 Hoechst Ag Verfahren zur Hydrierung von Nitrilgruppen enthaltenden Polymerisaten
FR2074027A5 (fr) * 1969-12-18 1971-10-01 Exploaterings Ab Tbf
FR2084750A5 (fr) * 1970-03-18 1971-12-17 Monsanto Co
FR2228785A1 (fr) * 1973-05-07 1974-12-06 Dorr Oliver Inc
FR2288748A1 (fr) * 1974-08-13 1976-05-21 Beecham Group Ltd Preparation d'enzyme comprenant un enzyme fixe sur des groupes non polaires et application a la preparation d'acide 6-amino-penicillanique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/59 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0216499A2 (fr) * 1985-08-23 1987-04-01 Courtaulds Plc Substrat polymère
EP0216499A3 (fr) * 1985-08-23 1989-02-22 Courtaulds Plc Substrat polymère

Also Published As

Publication number Publication date
JPS6247516B2 (fr) 1987-10-08
FR2417513B1 (fr) 1983-10-07
US4371612A (en) 1983-02-01
GB2090601A (en) 1982-07-14
US4486549A (en) 1984-12-04
GB2015001B (en) 1982-08-25
GB2090601B (en) 1983-02-23
DE2905671A1 (de) 1979-08-30
GB2015001A (en) 1979-09-05
DE2905671C2 (de) 1985-10-31
JPS5548392A (en) 1980-04-07

Similar Documents

Publication Publication Date Title
FR2417513A1 (fr) Materiau immobilise comportant une proteine biologiquement active liee a un support, sa preparation, et dispositif et procede l'utilisant
US5272087A (en) Enzymatic electrode and its preparation method
Arnold et al. Recent advances in the development and analytical applications of biosensing probes
Cahn Biosensors
Gouda et al. Enhancement of operational stability of an enzyme biosensor for glucose and sucrose using protein based stabilizing agents
Umana Protein-Modified Electrochemically Active Biomaterial Surface
Cremisini et al. Evaluation of the use of free and immobilised acetylcholinesterase for paraoxon detection with an amperometric choline oxidase based biosensor
Coulet Polymeric membranes and coupled enzymes in the design of biosensors
AU608875B2 (en) Sensor of the enzyme electrode type for the determination of an analyte
Fennouh et al. Increased paraoxon detection with solvents using acetylcholinesterase inactivation measured with a choline oxidase biosensor
Ikariyama et al. One step fabrication of microbiosensor prepared by the codeposition of enzyme and platinum particles
Schneider et al. Hydrogel matrix for three enzyme entrapment in creatine/creatinine amperometric biosensing
EP0250068B1 (fr) Senseur enzymatique
Marty et al. Amperometric determination of choline and acetylcholine with enzymes immobilized in a photocross-linkable polymer
Hlavay et al. Fibre-optic biosensor for hypoxanthine and xanthine based on a chemiluminescence reaction
US4780191A (en) L-glutamine sensor
Chang et al. Determination of glutamate pyruvate transaminase activity in clinical specimens using a biosensor composed of immobilized L-glutamate oxidase in a photo-crosslinkable polymer membrane on a palladium-deposited screen-printed carbon electrode
Mascini et al. Clinical uses of enzyme electrode probes
Chien-Yuan et al. Amperometric L-glutamate sensor using a novel L-glutamate oxidase from Streptomyces platensis NTU 3304
Laurinavicius et al. Amperometric glyceride biosensor
Turdean et al. Sensitive detection of organophosphorus pesticides using a needle type amperometric acetylcholinesterase-based bioelectrode. Thiocholine electrochemistry and immobilised enzyme inhibition
Thévenot Problems in adapting a glucose-oxidase electrochemical sensor into an implantable glucose-sensing device
Kumaran et al. Insecticide determination with enzyme electrodes using different enzyme immobilization techniques
FR2393535A1 (fr) Procede pour l'obtention de proteines alimentaires d'origine fongique ou a partir de micro-organismes pluricellulaires, dispositif de fermentation et proteines obtenues
Koochaki et al. The diffusion limited oxidase-based glucose enzyme electrode: relation between covering membrane permeability and substrate response

Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse