FR2416887A1 - Nouveaux derives de thioamides contenant un groupe pyridazine - Google Patents
Nouveaux derives de thioamides contenant un groupe pyridazineInfo
- Publication number
- FR2416887A1 FR2416887A1 FR7803663A FR7803663A FR2416887A1 FR 2416887 A1 FR2416887 A1 FR 2416887A1 FR 7803663 A FR7803663 A FR 7803663A FR 7803663 A FR7803663 A FR 7803663A FR 2416887 A1 FR2416887 A1 FR 2416887A1
- Authority
- FR
- France
- Prior art keywords
- derivs
- thioamide
- antiulcer
- prepd
- acid amide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 title abstract 2
- -1 sulphonyl halide Chemical class 0.000 title abstract 2
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 title 1
- 150000001408 amides Chemical class 0.000 title 1
- 230000000767 anti-ulcer Effects 0.000 title 1
- 150000002825 nitriles Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical group OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 abstract 2
- YQQSRZSUGBETRS-UHFFFAOYSA-N 1h-pyridazine-6-thione Chemical group SC1=CC=CN=N1 YQQSRZSUGBETRS-UHFFFAOYSA-N 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 2
- PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical group C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 abstract 2
- 208000008469 Peptic Ulcer Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 125000004001 thioalkyl group Chemical group 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/18—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7803663A FR2416887A1 (fr) | 1978-02-09 | 1978-02-09 | Nouveaux derives de thioamides contenant un groupe pyridazine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7803663A FR2416887A1 (fr) | 1978-02-09 | 1978-02-09 | Nouveaux derives de thioamides contenant un groupe pyridazine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2416887A1 true FR2416887A1 (fr) | 1979-09-07 |
| FR2416887B1 FR2416887B1 (enExample) | 1982-12-31 |
Family
ID=9204397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7803663A Granted FR2416887A1 (fr) | 1978-02-09 | 1978-02-09 | Nouveaux derives de thioamides contenant un groupe pyridazine |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2416887A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0030835A1 (en) * | 1979-12-05 | 1981-06-24 | Morishita Pharmaceutical Co. Ltd. | Derivatives of 2-substituted-6-phenyl-3(2H)pyridazinone, their production and pharmaceutical compositions containing them |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2712542A (en) * | 1952-05-14 | 1955-07-05 | Warner Hudnut Inc | New series of 2-(3-pyridazonyl)-acids and their derivatives and method of preparing members of the series |
| US2832780A (en) * | 1955-09-14 | 1958-04-29 | Warner Lambert Pharmaceutical | Hydrazides of pyridazonyl-substituted alkanoic acids |
| US3328403A (en) * | 1963-12-23 | 1967-06-27 | Chugai Pharmaceutical Co Ltd | 3-phenyl substituted-1-acetamidopyridazone derivatives and their preparation |
| FR2258178A1 (en) * | 1974-01-17 | 1975-08-18 | Ciba Geigy Ag | Alpha-heteroaryl-alkanethiocarboxamides - useful as gastric secretion inhibitors |
-
1978
- 1978-02-09 FR FR7803663A patent/FR2416887A1/fr active Granted
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2712542A (en) * | 1952-05-14 | 1955-07-05 | Warner Hudnut Inc | New series of 2-(3-pyridazonyl)-acids and their derivatives and method of preparing members of the series |
| US2832780A (en) * | 1955-09-14 | 1958-04-29 | Warner Lambert Pharmaceutical | Hydrazides of pyridazonyl-substituted alkanoic acids |
| US3328403A (en) * | 1963-12-23 | 1967-06-27 | Chugai Pharmaceutical Co Ltd | 3-phenyl substituted-1-acetamidopyridazone derivatives and their preparation |
| FR2258178A1 (en) * | 1974-01-17 | 1975-08-18 | Ciba Geigy Ag | Alpha-heteroaryl-alkanethiocarboxamides - useful as gastric secretion inhibitors |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0030835A1 (en) * | 1979-12-05 | 1981-06-24 | Morishita Pharmaceutical Co. Ltd. | Derivatives of 2-substituted-6-phenyl-3(2H)pyridazinone, their production and pharmaceutical compositions containing them |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2416887B1 (enExample) | 1982-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |