FR2411180A1 - Procede de preparation de 1-hydrocarbyl-2-(2',2',2'-trihalogeno-1'-hydroxyethyl)pyrroles - Google Patents

Procede de preparation de 1-hydrocarbyl-2-(2',2',2'-trihalogeno-1'-hydroxyethyl)pyrroles

Info

Publication number
FR2411180A1
FR2411180A1 FR7834471A FR7834471A FR2411180A1 FR 2411180 A1 FR2411180 A1 FR 2411180A1 FR 7834471 A FR7834471 A FR 7834471A FR 7834471 A FR7834471 A FR 7834471A FR 2411180 A1 FR2411180 A1 FR 2411180A1
Authority
FR
France
Prior art keywords
trihalogeno
pyrroles
hydrocarbyl
hydroxyethyl
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7834471A
Other languages
English (en)
Other versions
FR2411180B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP14658277A external-priority patent/JPS5481264A/ja
Priority claimed from JP14658177A external-priority patent/JPS5490171A/ja
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Publication of FR2411180A1 publication Critical patent/FR2411180A1/fr
Application granted granted Critical
Publication of FR2411180B1 publication Critical patent/FR2411180B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

L'INVENTION CONCERNE LA PRODUCTION DE 1-HYDROCARBYL-2-(2,2,2-TRIHALOGENO-1-HYDROXYETHYL)PYRROLES. ON OBTIENT CES COMPOSES PAR REACTION D'UN 1-HYDROCARBYLPYRROLE AVEC UN TRIHALOGENACETALDEHYDE EN PRESENCE D'UN ACIDE ORGANIQUE OU D'UNE RESINE D'ECHANGE CATIONIQUE. LES COMPOSES OBTENUS SONT UTILES POUR LA PREPARATION D'ACIDES 5-CYANO-1-HYDROCARBYLPYRROLE-2-ACETIQUES.
FR7834471A 1977-12-08 1978-12-07 Procede de preparation de 1-hydrocarbyl-2-(2',2',2'-trihalogeno-1'-hydroxyethyl)pyrroles Granted FR2411180A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14658277A JPS5481264A (en) 1977-12-08 1977-12-08 Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid
JP14658177A JPS5490171A (en) 1977-12-08 1977-12-08 5-cyano-1-methylpyrrole-2-acetic acid and its preparation

Publications (2)

Publication Number Publication Date
FR2411180A1 true FR2411180A1 (fr) 1979-07-06
FR2411180B1 FR2411180B1 (fr) 1982-07-09

Family

ID=26477382

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7834471A Granted FR2411180A1 (fr) 1977-12-08 1978-12-07 Procede de preparation de 1-hydrocarbyl-2-(2',2',2'-trihalogeno-1'-hydroxyethyl)pyrroles
FR7909463A Granted FR2414040A1 (fr) 1977-12-08 1979-04-13 Acides 5-cyano-1-hydrocarbylpyrrole-2-acetiques leur preparation et leur application a la production d'acides 5-acyles correspondants

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7909463A Granted FR2414040A1 (fr) 1977-12-08 1979-04-13 Acides 5-cyano-1-hydrocarbylpyrrole-2-acetiques leur preparation et leur application a la production d'acides 5-acyles correspondants

Country Status (16)

Country Link
US (1) US4238396A (fr)
AU (1) AU529229B2 (fr)
CA (1) CA1121364A (fr)
CH (1) CH644103A5 (fr)
DE (1) DE2852975C2 (fr)
DK (1) DK553378A (fr)
ES (1) ES475807A1 (fr)
FI (1) FI66848C (fr)
FR (2) FR2411180A1 (fr)
GB (1) GB2014131B (fr)
IE (1) IE47793B1 (fr)
IT (1) IT1157750B (fr)
LU (1) LU80620A1 (fr)
NL (1) NL7811940A (fr)
PH (2) PH15394A (fr)
SE (1) SE435278B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0038536A1 (fr) * 1980-04-18 1981-10-28 E.I. Du Pont De Nemours And Company 4,5-Diaryl-alpha-(polyfluoroalkyl)-1H-pyrrole-2-méthanamines anti-inflammatoires
EP0044485A1 (fr) * 1980-07-21 1982-01-27 E.I. Du Pont De Nemours And Company 2,3-Diaryl-5-(2,2,2-trifluoro-1-(trifluorométhyl)éthyl)-1H-pyrroles anti-inflammatoires

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359422A (en) * 1979-04-09 1982-11-16 Ethyl Corporation Acid stabilized compositions of 2,2,2-trichloro-1-(N-hydrocarbylpyrryl-2)-ethanol
US4246175A (en) 1979-05-29 1981-01-20 Ethyl Corporation Synthesis of 5-cyano-1-hydrocarbylpyrrole-2-acetic acid
US4528382A (en) * 1982-11-16 1985-07-09 Mcneilab, Inc. Imidoyl substituted pyrroles

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313852A (en) * 1960-06-03 1967-04-11 Smith Kline French Lab Trifluoromethyl substituted o-aminophenyl ketimines
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles
SE396949B (sv) * 1970-06-15 1977-10-10 Mcneilab Inc Forfarande for framstellning av aroyl-substituerade pyrroler med terapeutisk verkan
BE794161A (fr) * 1972-01-21 1973-07-17 Mcneilab Inc Acides 5-cinnamoyl-pyrrole-2-acetiques et leurs esters
US3803171A (en) * 1972-01-21 1974-04-09 Mc Neil Labor Inc 5-phenylacetyl-pyrroles
US3998844A (en) * 1975-06-02 1976-12-27 Mcneil Laboratories, Incorporated Uncatalyzed aroylation of 1-alkylpyrrole-2-acetic acid derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/69 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0038536A1 (fr) * 1980-04-18 1981-10-28 E.I. Du Pont De Nemours And Company 4,5-Diaryl-alpha-(polyfluoroalkyl)-1H-pyrrole-2-méthanamines anti-inflammatoires
EP0044485A1 (fr) * 1980-07-21 1982-01-27 E.I. Du Pont De Nemours And Company 2,3-Diaryl-5-(2,2,2-trifluoro-1-(trifluorométhyl)éthyl)-1H-pyrroles anti-inflammatoires

Also Published As

Publication number Publication date
DE2852975A1 (de) 1979-06-13
DK553378A (da) 1979-06-09
FI66848B (fi) 1984-08-31
IT7852240A0 (it) 1978-12-07
LU80620A1 (de) 1979-06-15
CA1121364A (fr) 1982-04-06
PH17068A (en) 1984-05-24
IT1157750B (it) 1987-02-18
FI783768A (fi) 1979-06-09
GB2014131B (en) 1982-09-02
FR2414040A1 (fr) 1979-08-03
IE47793B1 (en) 1984-06-27
US4238396A (en) 1980-12-09
DE2852975C2 (de) 1982-04-08
FR2411180B1 (fr) 1982-07-09
IE782419L (en) 1979-06-08
CH644103A5 (de) 1984-07-13
FI66848C (fi) 1984-12-10
GB2014131A (en) 1979-08-22
AU529229B2 (en) 1983-06-02
ES475807A1 (es) 1979-04-16
FR2414040B1 (fr) 1982-03-05
PH15394A (en) 1982-12-23
AU4231378A (en) 1979-06-14
SE435278B (sv) 1984-09-17
SE7811704L (sv) 1979-06-09
NL7811940A (nl) 1979-06-12

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