ES475807A1 - Un procedimiento para preparar acidos 5-acil-1-hidrocarbil- pirrol-2-acetico. - Google Patents

Un procedimiento para preparar acidos 5-acil-1-hidrocarbil- pirrol-2-acetico.

Info

Publication number
ES475807A1
ES475807A1 ES475807A ES475807A ES475807A1 ES 475807 A1 ES475807 A1 ES 475807A1 ES 475807 A ES475807 A ES 475807A ES 475807 A ES475807 A ES 475807A ES 475807 A1 ES475807 A1 ES 475807A1
Authority
ES
Spain
Prior art keywords
pyrrole
acetic acid
hydrocarbyl
hydrocarbylpyrrole
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES475807A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP14658277A external-priority patent/JPS5481264A/ja
Priority claimed from JP14658177A external-priority patent/JPS5490171A/ja
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Publication of ES475807A1 publication Critical patent/ES475807A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Un procedimiento para preparar ácidos 5-acil-l-hidrocarbilpirrol-2-acético, caracterizado porque se hace reaccionar un ácido 5-ciano-l-hidrocarbilpirrol-2-acético con un compuesto de Grignard y después se hidroliza el producto de reacción resultante.
ES475807A 1977-12-08 1978-12-07 Un procedimiento para preparar acidos 5-acil-1-hidrocarbil- pirrol-2-acetico. Expired ES475807A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14658277A JPS5481264A (en) 1977-12-08 1977-12-08 Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid
JP14658177A JPS5490171A (en) 1977-12-08 1977-12-08 5-cyano-1-methylpyrrole-2-acetic acid and its preparation

Publications (1)

Publication Number Publication Date
ES475807A1 true ES475807A1 (es) 1979-04-16

Family

ID=26477382

Family Applications (1)

Application Number Title Priority Date Filing Date
ES475807A Expired ES475807A1 (es) 1977-12-08 1978-12-07 Un procedimiento para preparar acidos 5-acil-1-hidrocarbil- pirrol-2-acetico.

Country Status (16)

Country Link
US (1) US4238396A (es)
AU (1) AU529229B2 (es)
CA (1) CA1121364A (es)
CH (1) CH644103A5 (es)
DE (1) DE2852975C2 (es)
DK (1) DK553378A (es)
ES (1) ES475807A1 (es)
FI (1) FI66848C (es)
FR (2) FR2411180A1 (es)
GB (1) GB2014131B (es)
IE (1) IE47793B1 (es)
IT (1) IT1157750B (es)
LU (1) LU80620A1 (es)
NL (1) NL7811940A (es)
PH (2) PH15394A (es)
SE (1) SE435278B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359422A (en) * 1979-04-09 1982-11-16 Ethyl Corporation Acid stabilized compositions of 2,2,2-trichloro-1-(N-hydrocarbylpyrryl-2)-ethanol
US4246175A (en) 1979-05-29 1981-01-20 Ethyl Corporation Synthesis of 5-cyano-1-hydrocarbylpyrrole-2-acetic acid
US4335136A (en) * 1980-04-18 1982-06-15 E. I. Du Pont De Nemours And Company Anti-inflammatory 4,5-diaryl-α-(polyfluoroalkyl)-1H-pyrrole-2-methanamines
EP0044485A1 (en) * 1980-07-21 1982-01-27 E.I. Du Pont De Nemours And Company Antiinflammatory 2,3-diaryl-5(2,2,2-trifluoro-1-(trifluoromethyl)-ethyl)-1H-pyrroles
US4528382A (en) * 1982-11-16 1985-07-09 Mcneilab, Inc. Imidoyl substituted pyrroles

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313852A (en) * 1960-06-03 1967-04-11 Smith Kline French Lab Trifluoromethyl substituted o-aminophenyl ketimines
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles
SE396949B (sv) * 1970-06-15 1977-10-10 Mcneilab Inc Forfarande for framstellning av aroyl-substituerade pyrroler med terapeutisk verkan
US3803171A (en) * 1972-01-21 1974-04-09 Mc Neil Labor Inc 5-phenylacetyl-pyrroles
BE794161A (fr) * 1972-01-21 1973-07-17 Mcneilab Inc Acides 5-cinnamoyl-pyrrole-2-acetiques et leurs esters
US3998844A (en) * 1975-06-02 1976-12-27 Mcneil Laboratories, Incorporated Uncatalyzed aroylation of 1-alkylpyrrole-2-acetic acid derivatives

Also Published As

Publication number Publication date
DE2852975A1 (de) 1979-06-13
LU80620A1 (de) 1979-06-15
GB2014131A (en) 1979-08-22
FR2411180B1 (es) 1982-07-09
FI66848C (fi) 1984-12-10
DK553378A (da) 1979-06-09
SE7811704L (sv) 1979-06-09
IE782419L (en) 1979-06-08
FR2411180A1 (fr) 1979-07-06
IT1157750B (it) 1987-02-18
NL7811940A (nl) 1979-06-12
FR2414040B1 (es) 1982-03-05
CA1121364A (en) 1982-04-06
AU529229B2 (en) 1983-06-02
IT7852240A0 (it) 1978-12-07
IE47793B1 (en) 1984-06-27
SE435278B (sv) 1984-09-17
US4238396A (en) 1980-12-09
FR2414040A1 (fr) 1979-08-03
PH17068A (en) 1984-05-24
FI783768A (fi) 1979-06-09
DE2852975C2 (de) 1982-04-08
FI66848B (fi) 1984-08-31
AU4231378A (en) 1979-06-14
PH15394A (en) 1982-12-23
CH644103A5 (de) 1984-07-13
GB2014131B (en) 1982-09-02

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971201