FR2408589A1 - Nouvelles 13,14-bisdeshydroprostaglandines, leur procede de preparation et leurs applications therapeutiques - Google Patents

Nouvelles 13,14-bisdeshydroprostaglandines, leur procede de preparation et leurs applications therapeutiques

Info

Publication number
FR2408589A1
FR2408589A1 FR7832270A FR7832270A FR2408589A1 FR 2408589 A1 FR2408589 A1 FR 2408589A1 FR 7832270 A FR7832270 A FR 7832270A FR 7832270 A FR7832270 A FR 7832270A FR 2408589 A1 FR2408589 A1 FR 2408589A1
Authority
FR
France
Prior art keywords
bisdeshydroproprostaglandins
news
preparation process
therapeutic applications
pharmacy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7832270A
Other languages
English (en)
Other versions
FR2408589B1 (fr
Inventor
Franco Faustine
Carlo Passarotti
Roberto Ceserani
Carmelo Gandolfi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlo Erba SpA filed Critical Carlo Erba SpA
Publication of FR2408589A1 publication Critical patent/FR2408589A1/fr
Application granted granted Critical
Publication of FR2408589B1 publication Critical patent/FR2408589B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)

Abstract

LES MEDICAMENTS SELON L'INVENTION SONT DES DERIVES DE PROSTAGLANDINE OPTIQUEMENT ACTIFS OU RACEMIQUES REPONDANT A LA FORMULE GENERALE: (CF DESSIN DANS BOPI) AINSI QUE LEURS SELS FORMES AVEC DES ACIDES OU DES BASES ACCEPTABLES EN PHARMACIE OU EN PHARMACIE VETERINAIRE. APPLICATIONS: POUR AMORCER LE TRAVAIL OU COMME ANTIULCEROGENES, EN PERFUSIONS INTRAVEINEUSES A 0,1-500GKG PAR MINUTE, A LA DOSE JOURNALIERE D'ENVIRON 0,1-20MGKG.
FR7832270A 1977-11-15 1978-11-15 Nouvelles 13,14-bisdeshydroprostaglandines, leur procede de preparation et leurs applications therapeutiques Granted FR2408589A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT29654/77A IT1088966B (it) 1977-11-15 1977-11-15 13,14-dideidro-prostaglandine

Publications (2)

Publication Number Publication Date
FR2408589A1 true FR2408589A1 (fr) 1979-06-08
FR2408589B1 FR2408589B1 (fr) 1983-10-07

Family

ID=11228185

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7832270A Granted FR2408589A1 (fr) 1977-11-15 1978-11-15 Nouvelles 13,14-bisdeshydroprostaglandines, leur procede de preparation et leurs applications therapeutiques

Country Status (8)

Country Link
US (1) US4551476A (fr)
JP (1) JPS5484555A (fr)
BE (1) BE871957A (fr)
DE (1) DE2847049C2 (fr)
FR (1) FR2408589A1 (fr)
GB (3) GB2085872B (fr)
IT (1) IT1088966B (fr)
ZA (1) ZA786075B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2517302A1 (fr) * 1981-11-27 1983-06-03 Erba Farmitalia Esters et amides de 13 14-bisdehydroprostaglandines

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2130575B (en) * 1982-11-09 1985-12-11 Erba Farmitalia Amide derivatives of 13, 14-didehydro-cycloalkyl-prostaglandins
GB8329559D0 (en) * 1983-11-04 1983-12-07 Erba Farmitalia Furyl derivatives of 16-substituted prostaglandins preparations
US5741810A (en) * 1996-02-29 1998-04-21 Allergan Cyclopentane heptan(ene)oic acid, 2- heteroarylalkenyl derivatives as therapeutic agents
WO2006137472A1 (fr) * 2005-06-24 2006-12-28 Taisho Pharmaceutical Co., Ltd. Dérivé de la prostaglandine

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2303533A1 (fr) * 1975-03-14 1976-10-08 Erba Carlo Spa Dehydro-13,14 desoxy-11 prostaglandines et procede de leur preparation
FR2316925A1 (fr) * 1975-06-27 1977-02-04 Erba Carlo Spa Dimethyl-16, 16 prostaglandines et procede de leur preparation
FR2376147A1 (fr) * 1976-12-31 1978-07-28 Erba Carlo Spa Prostaglandines bicycliques, utiles notamment comme anti-agglutinants des plaquettes sanguines et leur procede de preparation
FR2378757A1 (fr) * 1974-09-25 1978-08-25 Erba Carlo Spa Nor-o-heterocyclo-dehydro-13, 14 prostaglandines, leur procede de preparation et leur application comme medicaments

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378757A1 (fr) * 1974-09-25 1978-08-25 Erba Carlo Spa Nor-o-heterocyclo-dehydro-13, 14 prostaglandines, leur procede de preparation et leur application comme medicaments
FR2303533A1 (fr) * 1975-03-14 1976-10-08 Erba Carlo Spa Dehydro-13,14 desoxy-11 prostaglandines et procede de leur preparation
FR2316925A1 (fr) * 1975-06-27 1977-02-04 Erba Carlo Spa Dimethyl-16, 16 prostaglandines et procede de leur preparation
FR2376147A1 (fr) * 1976-12-31 1978-07-28 Erba Carlo Spa Prostaglandines bicycliques, utiles notamment comme anti-agglutinants des plaquettes sanguines et leur procede de preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2517302A1 (fr) * 1981-11-27 1983-06-03 Erba Farmitalia Esters et amides de 13 14-bisdehydroprostaglandines

Also Published As

Publication number Publication date
GB2085872B (en) 1982-12-08
IT1088966B (it) 1985-06-10
GB2085872A (en) 1982-05-06
DE2847049C2 (de) 1987-04-16
ZA786075B (en) 1979-10-31
GB2009145A (en) 1979-06-13
FR2408589B1 (fr) 1983-10-07
JPS5484555A (en) 1979-07-05
GB2086373A (en) 1982-05-12
US4551476A (en) 1985-11-05
DE2847049A1 (de) 1979-05-17
GB2009145B (en) 1982-08-11
GB2086373B (en) 1982-11-24
BE871957A (fr) 1979-03-01

Similar Documents

Publication Publication Date Title
FR2370723A1 (fr) Nouveaux aryl-acylamides n-(2-aminocycloaliphatiques), leur procede de preparation et medicament les contenant
ES2061094T3 (es) Un procedimiento para la obtencion de una formulacion para disminuir el deseo imperioso de alcohol (craving) en el tratamiento del alcoholismo cronico.
GEP20002298B (en) Benzimidazole Derivatives, Method of Their Production, Pharmaceutical Composition Containing the Same and Method for Its Treatment
TNSN86117A1 (fr) Nouvelles (piperazinyl 4-substitue) pyridazines utiles notamment comme medicaments analgesiques et antitussifs, et procede pour leur preparation
FR2370722A1 (fr) Nouveaux benzamides trans-n-(2-aminocycloaliphatiques), leur procede de preparation et medicament les contenant
FR2421174A1 (fr) Nouveaux derives de carbostyrile, leur procede de preparation et leurs applications en therapeutique
FR2362834A1 (fr) Nouveaux derives 6-hemicetal ou 6-ceto de prostaglandine, leur procede de preparation et medicament les contenant
FR2416889A1 (fr) Derives esters de l'acide dihydro-1,4-pyridine-dicarboxylique-3,5, medicaments a base de ces derives et leur procede de production
FR2386527A1 (fr) Nouvelles 2-alkyleneaminodihydropyridines, leur procede de preparation et medicament les contenant
FR2453155A1 (fr) Derives de cyanoguanidine, leur procede de preparation et leurs applications en therapeutique
TNSN87012A1 (fr) Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques
FR2354761A1 (fr) Acides n-aryl-anthraniliques, leurs procedes de preparation et compositions pharmaceutiques contenant lesdits acides anthraniliques
TNSN90021A1 (fr) Procede de preparation de tetrahydroimidazo (1,4) benzodiazepin -2- thiones antivirales
FR2361877A1 (fr) Nouvelles lactones d'acides libres du type prostaglandine, leur preparation et medicament les contenant
FR2408589A1 (fr) Nouvelles 13,14-bisdeshydroprostaglandines, leur procede de preparation et leurs applications therapeutiques
FR2359823A1 (fr) 2-benzyl-pyrrolidines, procede pour leur preparation et medicament contenant ces composes
FR2356642A1 (fr) La 2-bromo-6-fluoro-n-2-imidazolinylidene-benzamine, ses sels d'addition avec des acides, procedes pour leur preparation et les medicaments les renfermant
FR2432520A1 (fr) Nouvelles imidazoquinoxalines et leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
FR2450831A1 (fr) Derives de theobromine, leur preparation et leurs applications therapeutiques
FR2390424A1 (fr) Nouveaux derives d'amides de l'acide phenylacetique substitues, leur application en tant que medicament et leur application
FR2426686A1 (fr) Acides phenylaminothiophene-acetiques, leurs procedes de fabrication et medicaments les contenant
FR2385691A1 (fr) Nouveaux derives d'acides diarylmethyleneaminooxyalcanoiques, leur procede de preparation et medicament les contenant
FR2434804A1 (fr) Derives de la n-phenyl-indoline, leur preparation et leur application comme medicaments
FR2446831A1 (fr) Derive oxyimino-e-homo-eburnane, procede pour le preparer et son utilisation dans une composition pharmaceutique pour la preparation de derives ester de l'acide apovincaminique
BE900780A (fr) DERIVES DE LA CHLORO-4-FURO (3,4-c)-PYRIDINE, LEUR PROCEDE DE PREPARATION ET COMPOSITIONS THERAPEUTIQUES A BASE DE CES DERIVES.

Legal Events

Date Code Title Description
CD Change of name or company name
ST Notification of lapse