FR2404847A1 - METHOD FOR DETECTING TOXIC SUBSTANCES IN LIQUIDS - Google Patents

METHOD FOR DETECTING TOXIC SUBSTANCES IN LIQUIDS

Info

Publication number
FR2404847A1
FR2404847A1 FR7827822A FR7827822A FR2404847A1 FR 2404847 A1 FR2404847 A1 FR 2404847A1 FR 7827822 A FR7827822 A FR 7827822A FR 7827822 A FR7827822 A FR 7827822A FR 2404847 A1 FR2404847 A1 FR 2404847A1
Authority
FR
France
Prior art keywords
microorganism
luminous
liquids
substance
toxic substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7827822A
Other languages
French (fr)
Other versions
FR2404847B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc
Publication of FR2404847A1 publication Critical patent/FR2404847A1/en
Application granted granted Critical
Publication of FR2404847B1 publication Critical patent/FR2404847B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/18Water
    • G01N33/186Water using one or more living organisms, e.g. a fish
    • G01N33/1866Water using one or more living organisms, e.g. a fish using microorganisms

Abstract

L'invention concerne une méthode pour détecter une substance ou une condition toxique. Selon l'invention, on soumet une suspension aqueuse d'un micro-organisme lumineux à un contact avec une substance ou une condition suspectée d'être toxique pour le micro-organisme ; on détecte la lumière à la sortie du micro-organisme lumineux après contact avec la substance; et on compare la lumière à la sortie du micro-organisme lumineux sur ligne de base avant formation du mélange. On utilise un système 10 comprenant un récipient 12 contenant la suspension des micro-organismes lumineux, un détecteur de lumière 14, un amplificateur 16 et un appareil de mesure 18. L'invention s'applique notamment à l'examen de l'eau pour rechercher sa pollution.A method for detecting a toxic substance or condition is provided. According to the invention, an aqueous suspension of a luminous microorganism is subjected to contact with a substance or condition suspected of being toxic to the microorganism; the light is detected at the exit of the luminous microorganism after contact with the substance; and comparing the light to the output of the luminous microorganism on the baseline before the mixture is formed. A system 10 is used comprising a container 12 containing the suspension of luminous microorganisms, a light detector 14, an amplifier 16 and a measuring device 18. The invention applies in particular to the examination of water for look for its pollution.

FR7827822A 1977-09-28 1978-09-28 METHOD FOR DETECTING TOXIC SUBSTANCES IN LIQUIDS Granted FR2404847A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83749877A 1977-09-28 1977-09-28

Publications (2)

Publication Number Publication Date
FR2404847A1 true FR2404847A1 (en) 1979-04-27
FR2404847B1 FR2404847B1 (en) 1984-12-28

Family

ID=25274625

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7827822A Granted FR2404847A1 (en) 1977-09-28 1978-09-28 METHOD FOR DETECTING TOXIC SUBSTANCES IN LIQUIDS

Country Status (8)

Country Link
JP (1) JPS5458492A (en)
BE (1) BE870833A (en)
CA (1) CA1103050A (en)
DE (1) DE2841896C3 (en)
FR (1) FR2404847A1 (en)
GB (1) GB2005018B (en)
NL (1) NL7809821A (en)
SE (1) SE462166C (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1153218A (en) * 1980-03-25 1983-09-06 Malbone W. Greene Method and apparatus for monitoring light signals from liquid medium
WO1985000890A1 (en) * 1983-08-16 1985-02-28 Battelle Development Corporation Bioluminescent chemical system and method for detecting the presence of chemical agents in a medium
DE3833628A1 (en) * 1988-10-03 1990-04-12 Genlux Forschungsgesellschaft METHOD FOR DETECTING AND IDENTIFYING TOXIC SUBSTANCES USING CLONED MICROORGANISMS
WO1990004053A1 (en) * 1988-10-10 1990-04-19 Siemens Aktiengesellschaft Electric surface-polishing device
FR2680247B1 (en) * 1991-08-07 1993-11-12 Anjou Recherche Gie AUTOMATED POLLUTION DETECTOR IN AQUEOUS MEDIA USING A MICROORGANISM TEST.
GB9119382D0 (en) * 1991-09-11 1991-10-23 Knight Scient Ltd Apparatus for monitoring liquids
FR2686350B1 (en) * 1992-01-17 1996-12-27 Rochas METHOD FOR EVALUATING THE SAFETY OF PRODUCTS USING BIOLUMINESCENCE MEASUREMENTS.
DE4230264A1 (en) * 1992-09-10 1994-03-17 Bayer Ag Analytical method for the investigation of mixtures for toxic components
GB2279738A (en) * 1993-06-18 1995-01-11 Yorkshire Water Plc Determining toxicity in fluid samples
DE4325482C1 (en) * 1993-07-29 1994-12-15 Lange Gmbh Dr Bruno Medium for reactivating preserved microorganisms
DE69430992T2 (en) * 1993-09-08 2003-02-06 Merck Patent Gmbh METHOD FOR TESTING AN ANALYT
DE4332165A1 (en) * 1993-09-22 1995-03-23 Kolibri Umweltanalytik Und On Method and apparatus for pollutant analysis of water samples
WO1995010767A1 (en) * 1993-10-15 1995-04-20 Merck Patent Gmbh Assay method
DE4401169C2 (en) * 1994-01-17 2003-01-09 Buehler Ag Process for distinguishing the quality of liquids
DE4401868C1 (en) * 1994-01-22 1995-02-16 Lobbe Xenex Gmbh Microbial method for detecting pollutants
GB2293878A (en) * 1994-10-06 1996-04-10 Stephen John Shore Monitoring biocide content of industrial waters
WO1996014570A1 (en) * 1994-11-07 1996-05-17 Idexx Laboratories, Inc. Self-contained signal generating sampling device and methods of use of same
GB0510709D0 (en) 2005-05-26 2005-06-29 Cymtox Ltd Water monitoring system
US7704731B2 (en) * 2006-10-10 2010-04-27 The United States Of America As Represented By The Secretary Of The Navy System and method for quantifying toxicity in water, soil, and sediments
CN112198150B (en) * 2020-07-07 2022-10-25 山东省临沂生态环境监测中心 Method for monitoring polluted water body by bioluminescence method
CN113340885B (en) * 2021-06-23 2022-08-09 同济大学 Formaldehyde biological monitoring device and monitoring method

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3370175A (en) * 1965-01-28 1968-02-20 North American Rockwell Toxicant detector
US3679312A (en) * 1971-06-16 1972-07-25 Technicon Instr Method and apparatus for measuring bioluminescence or chemiluminescence for quantitative analysis of samples
US3849653A (en) * 1973-09-27 1974-11-19 Bausch & Lomb Multichannel bioluminescent sensors
US3958938A (en) * 1974-12-16 1976-05-25 Bausch & Lomb Incorporated Bioluminescent sensor system
AU1876276A (en) * 1975-10-20 1978-04-20 University Of Sydney, The Photoelectric analysis using luminous bacteria
FR2374643A1 (en) * 1976-12-14 1978-07-13 Univ California NEW TITRATION METHOD USING LOCALIZED SOURCES OF ELECTROMAGNETIC RADIATION

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3797999A (en) * 1970-05-20 1974-03-19 Aerojet General Co Method and apparatus for indicating micro-organic matter by means of chemiluminescence

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3370175A (en) * 1965-01-28 1968-02-20 North American Rockwell Toxicant detector
US3679312A (en) * 1971-06-16 1972-07-25 Technicon Instr Method and apparatus for measuring bioluminescence or chemiluminescence for quantitative analysis of samples
US3849653A (en) * 1973-09-27 1974-11-19 Bausch & Lomb Multichannel bioluminescent sensors
US3958938A (en) * 1974-12-16 1976-05-25 Bausch & Lomb Incorporated Bioluminescent sensor system
AU1876276A (en) * 1975-10-20 1978-04-20 University Of Sydney, The Photoelectric analysis using luminous bacteria
AU508807B2 (en) * 1975-10-20 1980-04-03 University Of Sydney, The Photoelectric analysis using luminous bacteria
FR2374643A1 (en) * 1976-12-14 1978-07-13 Univ California NEW TITRATION METHOD USING LOCALIZED SOURCES OF ELECTROMAGNETIC RADIATION

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
CA1958 *
CA1959 *
CA1963 *
CA1965 *
CA1971 *
CA1976 *
EXBK/56 *
EXBK/75 *

Also Published As

Publication number Publication date
SE7810154L (en) 1979-03-29
DE2841896A1 (en) 1979-03-29
SE462166C (en) 1997-01-16
BE870833A (en) 1979-01-15
DE2841896C2 (en) 1991-10-24
GB2005018A (en) 1979-04-11
JPS5458492A (en) 1979-05-11
NL7809821A (en) 1979-03-30
GB2005018B (en) 1982-07-14
CA1103050A (en) 1981-06-16
FR2404847B1 (en) 1984-12-28
JPS5728272B2 (en) 1982-06-15
DE2841896C3 (en) 1996-09-26
SE462166B (en) 1990-05-14

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Legal Events

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