FR2399249A1 - OPHTHALMIC COMPOSITIONS CONTAINING 1,3-DIOXO-1H-BENZ (D, E) ISOQUINOLINE-2 (3H) -ACETIC ACID - Google Patents

OPHTHALMIC COMPOSITIONS CONTAINING 1,3-DIOXO-1H-BENZ (D, E) ISOQUINOLINE-2 (3H) -ACETIC ACID

Info

Publication number
FR2399249A1
FR2399249A1 FR7822648A FR7822648A FR2399249A1 FR 2399249 A1 FR2399249 A1 FR 2399249A1 FR 7822648 A FR7822648 A FR 7822648A FR 7822648 A FR7822648 A FR 7822648A FR 2399249 A1 FR2399249 A1 FR 2399249A1
Authority
FR
France
Prior art keywords
dioxo
acetic acid
benz
isoquinoline
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7822648A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of FR2399249A1 publication Critical patent/FR2399249A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Abstract

L'invention concerne une composition pharmaceutique pour une application topique, permettant d'empêcher ou de soulager les complications associées au diabète mellitus, se composant de cataractes et de rétinopathie. Selon l'invention, elle comprend une solution aqueuse à pH de l'ordre de 6, d'environ 0,5 % à environ 1,5 % d'hydroxyéthyl cellulose et d'environ 2,0 % à environ 12,5 % d'acide 1,3-dioxo-1H-benzØd,eõisoquinoline-2(3H)-acétique. L'invention s'applique notamment aux soins ophtalmiques.Disclosed is a pharmaceutical composition for topical application, for preventing or alleviating complications associated with diabetes mellitus, consisting of cataracts and retinopathy. According to the invention, it comprises an aqueous solution at a pH of the order of 6, from about 0.5% to about 1.5% of hydroxyethyl cellulose and from about 2.0% to about 12.5%. 1,3-dioxo-1H-benzØd, eõisoquinolin-2 (3H) -acetic acid. The invention applies in particular to ophthalmic care.

FR7822648A 1977-08-01 1978-07-31 OPHTHALMIC COMPOSITIONS CONTAINING 1,3-DIOXO-1H-BENZ (D, E) ISOQUINOLINE-2 (3H) -ACETIC ACID Withdrawn FR2399249A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82105177A 1977-08-01 1977-08-01

Publications (1)

Publication Number Publication Date
FR2399249A1 true FR2399249A1 (en) 1979-03-02

Family

ID=25232373

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7822648A Withdrawn FR2399249A1 (en) 1977-08-01 1978-07-31 OPHTHALMIC COMPOSITIONS CONTAINING 1,3-DIOXO-1H-BENZ (D, E) ISOQUINOLINE-2 (3H) -ACETIC ACID

Country Status (9)

Country Link
JP (1) JPS5428810A (en)
AT (1) AT361124B (en)
AU (1) AU3846578A (en)
BE (1) BE869384A (en)
ES (1) ES472892A1 (en)
FR (1) FR2399249A1 (en)
GB (1) GB2001529B (en)
IT (1) IT1097996B (en)
ZA (1) ZA784247B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58144701A (en) * 1982-02-23 1983-08-29 Kawasaki Steel Corp Method and measuring tool for measuring thickness of covering layer of bathed surface of melted metal bath
JPS613011A (en) * 1984-06-15 1986-01-09 Heishin Kikai Kogyo Kk Liquid interface detector
GB2169508B (en) * 1985-01-11 1989-02-01 Smith & Nephew Ass Ophthalmic compositions and use
JPS61243302A (en) * 1985-04-20 1986-10-29 Kumagai Gumi Ltd Concrete tunnel lining thickness detector
DE4225489A1 (en) * 1992-07-30 1994-02-03 Michael Prof Dr Rer Na Dittgen Aq. eye-drops contg. adhesive bio-polymer, e.g. polyvinyl alcohol and acid - adhere well to the cornea, provide better and longer lasting delivery of active ingredient e.g. pilocarpine
EP0938896A1 (en) 1998-01-15 1999-09-01 Novartis AG Autoclavable pharmaceutical compositions containing a chelating agent

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB784059A (en) * 1954-03-18 1957-10-02 Basf Ag Improvements in the production of polyester amides
FR1494741A (en) * 1965-07-20 1967-09-15 Merck & Co Inc Production of a stable aqueous base for ophthalmic products
FR2073437A1 (en) * 1969-12-01 1971-10-01 Burton Parsons Chemicals Inc
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US3843782A (en) * 1971-07-26 1974-10-22 Flow Pharma Inc Eye solution and method of using same
FR2230358A2 (en) * 1973-05-25 1974-12-20 Fisons Ltd Cromoglycate contg. solns. - contg. a second therapeutically active cpd. e.g. an antihistamine
DE2526998A1 (en) * 1974-04-23 1977-01-13 Burton Parsons & Co OPHTHALMIC SOLUTION
FR2333500A1 (en) * 1975-12-04 1977-07-01 Alcon Lab Inc OPHTHALMIC SOLUTION BASED ON POLYSACCHARIDE, BENZALKONIUM CHLORIDE AND WATER

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB784059A (en) * 1954-03-18 1957-10-02 Basf Ag Improvements in the production of polyester amides
FR1494741A (en) * 1965-07-20 1967-09-15 Merck & Co Inc Production of a stable aqueous base for ophthalmic products
FR2073437A1 (en) * 1969-12-01 1971-10-01 Burton Parsons Chemicals Inc
GB1340518A (en) * 1969-12-01 1973-12-12 Burton Parsons Chemicals Inc Opthalmic solution
GB1340516A (en) * 1969-12-01 1973-12-12 Burton Parsons Chemicals Inc Ophthalmic solution
US3843782A (en) * 1971-07-26 1974-10-22 Flow Pharma Inc Eye solution and method of using same
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
FR2230358A2 (en) * 1973-05-25 1974-12-20 Fisons Ltd Cromoglycate contg. solns. - contg. a second therapeutically active cpd. e.g. an antihistamine
DE2526998A1 (en) * 1974-04-23 1977-01-13 Burton Parsons & Co OPHTHALMIC SOLUTION
FR2333500A1 (en) * 1975-12-04 1977-07-01 Alcon Lab Inc OPHTHALMIC SOLUTION BASED ON POLYSACCHARIDE, BENZALKONIUM CHLORIDE AND WATER

Also Published As

Publication number Publication date
GB2001529B (en) 1982-06-16
ATA551678A (en) 1980-07-15
JPS5428810A (en) 1979-03-03
IT7826317A0 (en) 1978-07-31
AU3846578A (en) 1980-02-07
BE869384A (en) 1979-01-29
AT361124B (en) 1981-02-25
GB2001529A (en) 1979-02-07
IT1097996B (en) 1985-08-31
ZA784247B (en) 1980-02-27
ES472892A1 (en) 1979-10-16

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