FR2398111A1 - Nouvel antibiotique du type anthracycline produit par fermentation, son procede de production et medicament le contenant - Google Patents
Nouvel antibiotique du type anthracycline produit par fermentation, son procede de production et medicament le contenantInfo
- Publication number
- FR2398111A1 FR2398111A1 FR7821150A FR7821150A FR2398111A1 FR 2398111 A1 FR2398111 A1 FR 2398111A1 FR 7821150 A FR7821150 A FR 7821150A FR 7821150 A FR7821150 A FR 7821150A FR 2398111 A1 FR2398111 A1 FR 2398111A1
- Authority
- FR
- France
- Prior art keywords
- fermentation
- production process
- new antibiotic
- product containing
- medicinal product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/907—Streptosporangium
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention a trait au domaine de la chimie médicale. Elle concerne un antibiotique nouveau du type anthracycline, appelé rudolphomycine, produit par fermentation d'Actinosporangium sp. ATCC 31 127 et isolément sous une forme dénuée de substances produites simultanément. La rudolphomycine et ses sels acceptables du point de vue pharmaceutique sont doués d'activité antimicrobienne et inhibent le développement de tumeurs chez les mammifères.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81642777A | 1977-07-18 | 1977-07-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2398111A1 true FR2398111A1 (fr) | 1979-02-16 |
FR2398111B1 FR2398111B1 (fr) | 1983-04-01 |
Family
ID=25220576
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7821150A Granted FR2398111A1 (fr) | 1977-07-18 | 1978-07-17 | Nouvel antibiotique du type anthracycline produit par fermentation, son procede de production et medicament le contenant |
Country Status (6)
Country | Link |
---|---|
US (2) | US4123608A (fr) |
CA (1) | CA1110562A (fr) |
DE (1) | DE2831535A1 (fr) |
FR (1) | FR2398111A1 (fr) |
GB (1) | GB2001052B (fr) |
IT (1) | IT1105531B (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4123608A (en) * | 1977-07-18 | 1978-10-31 | Bristol-Myers Company | Antibiotic compound |
US4977084A (en) * | 1989-02-16 | 1990-12-11 | Board Of Trustees Operating Michigan State University | Production, isolation, and identification of novel antifungal compounds |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2347381A1 (fr) * | 1976-04-07 | 1977-11-04 | Microbial Chem Res Found | Nouveaux derives d'anthracycline-glycosides, en particulier designes sous le nom d'antibiotiques ma 144-m1 et ma 144-m2, leurs procedes de preparation et compositions pharmaceutiques contenant lesdits composes comme agents antitumeurs |
FR2348224A1 (fr) * | 1976-04-15 | 1977-11-10 | Bristol Myers Co | Nouvel antibiotique du type anthracycline et son procede de preparation |
FR2362157A1 (fr) * | 1976-08-16 | 1978-03-17 | Microbial Chem Res Found | Anthracyclines glycosides nouvelles et leur application pharmacologique |
DE2743654A1 (de) * | 1976-10-05 | 1978-04-06 | Microbial Chem Res Found | Anthracyclinglycosid |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB846130A (en) * | 1956-03-23 | 1960-08-24 | Ciba Ltd | New antibiotic and derivatives and salts thereof, preparations containing the same and process for the manufacture of these substances |
US3864480A (en) * | 1974-05-06 | 1975-02-04 | Merck & Co Inc | Cinerubin A and B As Antiparasitic Agents |
US4123608A (en) * | 1977-07-18 | 1978-10-31 | Bristol-Myers Company | Antibiotic compound |
-
1978
- 1978-01-25 US US05/872,291 patent/US4123608A/en not_active Expired - Lifetime
- 1978-05-30 US US05/910,408 patent/US4162938A/en not_active Expired - Lifetime
- 1978-06-20 CA CA305,861A patent/CA1110562A/fr not_active Expired
- 1978-06-27 GB GB7828078A patent/GB2001052B/en not_active Expired
- 1978-07-13 IT IT50291/78A patent/IT1105531B/it active
- 1978-07-17 FR FR7821150A patent/FR2398111A1/fr active Granted
- 1978-07-18 DE DE19782831535 patent/DE2831535A1/de not_active Withdrawn
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2347381A1 (fr) * | 1976-04-07 | 1977-11-04 | Microbial Chem Res Found | Nouveaux derives d'anthracycline-glycosides, en particulier designes sous le nom d'antibiotiques ma 144-m1 et ma 144-m2, leurs procedes de preparation et compositions pharmaceutiques contenant lesdits composes comme agents antitumeurs |
FR2348224A1 (fr) * | 1976-04-15 | 1977-11-10 | Bristol Myers Co | Nouvel antibiotique du type anthracycline et son procede de preparation |
FR2362157A1 (fr) * | 1976-08-16 | 1978-03-17 | Microbial Chem Res Found | Anthracyclines glycosides nouvelles et leur application pharmacologique |
DE2743654A1 (de) * | 1976-10-05 | 1978-04-06 | Microbial Chem Res Found | Anthracyclinglycosid |
FR2403350A1 (fr) * | 1976-10-05 | 1979-04-13 | Microbial Chem Res Found | Nouvelle anthracycline antibiotique contre les tumeurs |
Non-Patent Citations (4)
Title |
---|
EXBK/ * |
EXBK/72 * |
EXBK/77 * |
EXBK/79 * |
Also Published As
Publication number | Publication date |
---|---|
IT7850291A0 (it) | 1978-07-13 |
US4162938A (en) | 1979-07-31 |
GB2001052A (en) | 1979-01-24 |
IT1105531B (it) | 1985-11-04 |
FR2398111B1 (fr) | 1983-04-01 |
GB2001052B (en) | 1982-01-13 |
DE2831535A1 (de) | 1979-03-08 |
CA1110562A (fr) | 1981-10-13 |
US4123608A (en) | 1978-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |