FR2367055A1 - Nouveaux derives d'alcanolamines, leur procede de preparation et composition pharmaceutique les contenant - Google Patents

Nouveaux derives d'alcanolamines, leur procede de preparation et composition pharmaceutique les contenant

Info

Publication number
FR2367055A1
FR2367055A1 FR7730149A FR7730149A FR2367055A1 FR 2367055 A1 FR2367055 A1 FR 2367055A1 FR 7730149 A FR7730149 A FR 7730149A FR 7730149 A FR7730149 A FR 7730149A FR 2367055 A1 FR2367055 A1 FR 2367055A1
Authority
FR
France
Prior art keywords
alcanolamines
pharmaceutical composition
composition containing
preparation process
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7730149A
Other languages
English (en)
Other versions
FR2367055B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of FR2367055A1 publication Critical patent/FR2367055A1/fr
Application granted granted Critical
Publication of FR2367055B1 publication Critical patent/FR2367055B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/48—Y being a hydrogen or a carbon atom
    • C07C275/50—Y being a hydrogen or an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des dérivés nouveaux d'alcanolamines et leurs sels d'addition d'acides. Elle concerne également un procédé de préparation de ces composés. Les nouveaux composés de l'invention sont doués d'activité de blocage des récepteurs beta -adrénergiques.
FR7730149A 1976-10-07 1977-10-06 Nouveaux derives d'alcanolamines, leur procede de preparation et composition pharmaceutique les contenant Granted FR2367055A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB41714/76A GB1540463A (en) 1976-10-07 1976-10-07 Alkanolamine derivatives

Publications (2)

Publication Number Publication Date
FR2367055A1 true FR2367055A1 (fr) 1978-05-05
FR2367055B1 FR2367055B1 (fr) 1981-11-27

Family

ID=10421024

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7730149A Granted FR2367055A1 (fr) 1976-10-07 1977-10-06 Nouveaux derives d'alcanolamines, leur procede de preparation et composition pharmaceutique les contenant

Country Status (5)

Country Link
US (4) US4211878A (fr)
JP (1) JPS5346927A (fr)
DE (1) DE2745222A1 (fr)
FR (1) FR2367055A1 (fr)
GB (1) GB1540463A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2403993A1 (fr) * 1977-09-22 1979-04-20 Ici Ltd Nouveaux derives d'alcanolamines, leur procede de production et composition pharmaceutique les contenant.
EP0172446A2 (fr) * 1984-08-02 1986-02-26 Roche Diagnostics GmbH Application de dérivés d'alcoylène-diamines pour le traitement de troubles d'irrigation sanguine ainsi que les médicaments qui contiennent ces composés

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1540463A (en) * 1976-10-07 1979-02-14 Ici Ltd Alkanolamine derivatives
DE2962383D1 (en) * 1978-06-15 1982-05-06 Ici Plc Anti-inflammatory 1-phenyl-2-aminoethanol derivatives, pharmaceutical compositions thereof for topical use, and processes for their manufacture
ZW9580A1 (en) * 1979-05-21 1981-12-23 Ici Ltd 1-phenyl-2-aminoethanol derivatives
IE52345B1 (en) * 1981-02-02 1987-09-16 Ici Plc Alkanolamine derivatives
DE3361244D1 (de) * 1982-01-29 1986-01-02 Ici Plc Alkanolamine derivatives
CA1219865A (fr) * 1982-05-14 1987-03-31 Leo Alig Derives de phenethanolamine d'aziridine
US4849527A (en) * 1982-09-13 1989-07-18 Bristol-Myers Company Process for resolution of optical isomers
DE3512627A1 (de) * 1985-04-06 1986-10-09 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel
CA2141435A1 (fr) * 1992-07-30 1994-02-17 William Byrne Ester d'un nitrate organique et d'un salicylate
WO2001062711A2 (fr) * 2000-02-22 2001-08-30 Cv Therapeutics, Inc. Composes alkylene diamine substitues

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2210407A1 (fr) * 1972-12-15 1974-07-12 Ici Ltd
FR2254325A2 (fr) * 1972-12-15 1975-07-11 Ici Ltd
FR2273522A2 (fr) * 1974-06-05 1976-01-02 Ici Ltd Nouveau derive d'alcanolamine, son procede de preparation et medicament le contenant
FR2333498A2 (fr) * 1972-12-15 1977-07-01 Ici Ltd Composes azotes

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1178400A (en) * 1966-12-13 1970-01-21 Delalande Sa Nitrogen Substituted Amines and their process of Preparation.
US3607859A (en) * 1968-06-12 1971-09-21 Monsanto Co Furylacryloylgly-clycyl-l-leucinamide and relateo peptides and use thereof in spectrophotometric assay for neutral protease
JPS5231858B1 (fr) * 1969-12-17 1977-08-17
US4131685A (en) * 1972-12-15 1978-12-26 Imperial Chemical Industries Limited Pharmaceutical compositions and uses of alkanolamine derivatives
US4167581A (en) * 1972-12-15 1979-09-11 Imperial Chemical Industries Limited Alkanolamine derivatives and pharmaceutical compositions and uses thereof
US4171374A (en) * 1972-12-15 1979-10-16 Imperial Chemical Industries Limited Alkanolamine derivatives
US4083992A (en) * 1972-12-15 1978-04-11 Imperial Chemical Industries Limited Alkanolamine derivatives
ZA741812B (en) * 1973-04-18 1975-04-30 Haessle A New amines and process for their preparation
US4117157A (en) * 1973-06-22 1978-09-26 Imperial Chemical Industries Limited Ethanolamine derivatives having β-adrenergic blocking activity
FI65987C (fi) * 1973-12-12 1984-08-10 Ici Ltd Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat
US4041075A (en) * 1973-12-12 1977-08-09 Imperial Chemical Industries Limited Phenoxy-alkanolamine derivatives
GB1540463A (en) * 1976-10-07 1979-02-14 Ici Ltd Alkanolamine derivatives

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2210407A1 (fr) * 1972-12-15 1974-07-12 Ici Ltd
FR2254325A2 (fr) * 1972-12-15 1975-07-11 Ici Ltd
FR2333498A2 (fr) * 1972-12-15 1977-07-01 Ici Ltd Composes azotes
FR2273522A2 (fr) * 1974-06-05 1976-01-02 Ici Ltd Nouveau derive d'alcanolamine, son procede de preparation et medicament le contenant

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2403993A1 (fr) * 1977-09-22 1979-04-20 Ici Ltd Nouveaux derives d'alcanolamines, leur procede de production et composition pharmaceutique les contenant.
EP0172446A2 (fr) * 1984-08-02 1986-02-26 Roche Diagnostics GmbH Application de dérivés d'alcoylène-diamines pour le traitement de troubles d'irrigation sanguine ainsi que les médicaments qui contiennent ces composés
EP0172446A3 (fr) * 1984-08-02 1989-07-26 Roche Diagnostics GmbH Application de dérivés d'alcoylène-diamines pour le traitement de troubles d'irrigation sanguine ainsi que les médicaments qui contiennent ces composés

Also Published As

Publication number Publication date
DE2745222A1 (de) 1978-04-20
US4211878A (en) 1980-07-08
JPS5346927A (en) 1978-04-27
FR2367055B1 (fr) 1981-11-27
US4346111A (en) 1982-08-24
GB1540463A (en) 1979-02-14
US4318921A (en) 1982-03-09
US4419363A (en) 1983-12-06

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Legal Events

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