FR2397834A1 - Compositions radiographiques - Google Patents
Compositions radiographiquesInfo
- Publication number
- FR2397834A1 FR2397834A1 FR7821046A FR7821046A FR2397834A1 FR 2397834 A1 FR2397834 A1 FR 2397834A1 FR 7821046 A FR7821046 A FR 7821046A FR 7821046 A FR7821046 A FR 7821046A FR 2397834 A1 FR2397834 A1 FR 2397834A1
- Authority
- FR
- France
- Prior art keywords
- group
- acid
- carbon atoms
- radiographic
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- 229940120146 EDTMP Drugs 0.000 abstract 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical compound OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000008139 complexing agent Substances 0.000 abstract 1
- NFDRPXJGHKJRLJ-UHFFFAOYSA-N edtmp Chemical compound OP(O)(=O)CN(CP(O)(O)=O)CCN(CP(O)(O)=O)CP(O)(O)=O NFDRPXJGHKJRLJ-UHFFFAOYSA-N 0.000 abstract 1
- 229910052735 hafnium Inorganic materials 0.000 abstract 1
- VBJZVLUMGGDVMO-UHFFFAOYSA-N hafnium atom Chemical compound [Hf] VBJZVLUMGGDVMO-UHFFFAOYSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 229910052715 tantalum Inorganic materials 0.000 abstract 1
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/10—Polyhydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/10—Polyhydroxy carboxylic acids
- C07C59/105—Polyhydroxy carboxylic acids having five or more carbon atoms, e.g. aldonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/255—Tartaric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/265—Citric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne des complexes hydratés. Il s'agit d'un complexe hydraté soluble dans l'eau, non toxique, d'un métal choisi dans le groupe constitué par l'hafnium et le tantale, et d'un agent complexant acide organique choisi dans le groupe suivant : a. Les acides organiques ayant entre 2 et 7 atomes de carbone et au moins un groupe hydroxyle ; b. Les acides aminés contenant de 2 à 8 atomes de carbone; et c. Un acide phosphonique choisi parmi le groupe constitué par l'acide éthylènediaminetétraméthylènephosphonique, l'acide diéthylènepentaméthylènephosphonique, et les acides disphophoniques représentés par la formule :
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/816,618 US4176173A (en) | 1977-07-18 | 1977-07-18 | Radiographic compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2397834A1 true FR2397834A1 (fr) | 1979-02-16 |
Family
ID=25221144
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7821046A Withdrawn FR2397834A1 (fr) | 1977-07-18 | 1978-07-13 | Compositions radiographiques |
Country Status (5)
Country | Link |
---|---|
US (1) | US4176173A (fr) |
JP (1) | JPS5422327A (fr) |
DE (1) | DE2831524A1 (fr) |
FR (1) | FR2397834A1 (fr) |
GB (1) | GB2001969B (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3129906C3 (de) * | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
US4647447A (en) * | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
US4957939A (en) * | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
US4478816A (en) * | 1982-06-07 | 1984-10-23 | Georgetown University | Rare earth/chelating agent complex for digital fluoroscopy |
NL194579C (nl) * | 1983-01-21 | 2002-08-05 | Schering Ag | Diagnostisch middel. |
US5204085A (en) * | 1985-01-08 | 1993-04-20 | Mallinckrodt Medical, Inc. | Method for enhancing the safety of metal-ligand chelates as X-ray contrast agents |
JPS63251707A (ja) * | 1987-04-06 | 1988-10-19 | Uchida Seisakusho:Kk | 石油燃焼器具の芯上下装置 |
JPS63251706A (ja) * | 1987-04-06 | 1988-10-19 | Uchida Seisakusho:Kk | 石油燃焼器具の芯昇降装置 |
JPS641220U (fr) * | 1987-06-19 | 1989-01-06 | ||
JPS6438462U (fr) * | 1987-09-02 | 1989-03-08 | ||
GB9006977D0 (en) * | 1990-03-28 | 1990-05-23 | Nycomed As | Compositions |
IT1246380B (it) * | 1990-04-12 | 1994-11-18 | Bracco Spa | Sali insolubili di lantanidi per la visualizzazione in risonanza magnetica nucleare del tratto gastro-intestinale |
CA2106976A1 (fr) * | 1991-03-27 | 1992-09-28 | Torsten Almen | Produit de contraste |
DE69231966T2 (de) | 1991-08-05 | 2001-11-15 | Mallinckrodt Inc | Schwermetallcluster zur verwendung als abbildungsmittel |
GB2317177A (en) * | 1996-09-13 | 1998-03-18 | British Steel Plc | Organic phosphonates and metal complexes thereof for use as coating agents and especially for pretreating steel |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2151706B1 (en) * | 1971-10-18 | 1973-05-03 | Cegla, Ulrich, Dr med , 600 0 Frank fürt Niederrad | Tantalum-contg x-ray contrast agents - in aerosol form for bronchography |
US3937800A (en) * | 1972-07-17 | 1976-02-10 | Dure Smith Peter | Bronchographic x-ray contrast method |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB238543A (en) * | 1924-08-13 | 1926-03-11 | Philips Nv | Improved process for converting hafnium and zirconium phosphates into other hafnium and zirconium compounds |
AT202551B (de) * | 1956-06-02 | 1959-03-10 | Kurt Dipl Ing Dr Phil D Peters | Verfahren zur Herstellung von Komplexverbindungen |
DK100609C (da) * | 1958-09-06 | 1964-12-21 | Henkel & Cie Gmbh | Fremgangsmåde til ved kompleksdannelse at binde ioner af di- og trivalente metaller i opløsninger. |
DE1110822B (de) * | 1960-09-12 | 1961-07-13 | Pierre Castel | Roentgenkontrastmittel |
US3198817A (en) * | 1960-11-08 | 1965-08-03 | Dow Chemical Co | Insoluble chelates of titanium, zirconium, hafnium and thorium |
GB1054265A (fr) * | 1962-11-07 | 1900-01-01 | ||
US4020091A (en) * | 1965-10-28 | 1977-04-26 | Plains Chemical Development Co. | Chelation |
SE397473B (sv) * | 1974-03-14 | 1977-11-07 | Pharmacia Ab | Anvendningen av polymerpartiklar som tillsatsmedel i rontgenkontrastmedel baserade pa bariumsulfat eller liknande |
US4029696A (en) * | 1976-04-09 | 1977-06-14 | Benckiser-Knapsack Gmbh | N-hydroxy alkane amino alkane diphosphonic acids, process of producing same, and compositions for and method of using same |
-
1977
- 1977-07-18 US US05/816,618 patent/US4176173A/en not_active Expired - Lifetime
-
1978
- 1978-07-13 FR FR7821046A patent/FR2397834A1/fr not_active Withdrawn
- 1978-07-17 GB GB7830051A patent/GB2001969B/en not_active Expired
- 1978-07-17 JP JP8619678A patent/JPS5422327A/ja active Granted
- 1978-07-18 DE DE19782831524 patent/DE2831524A1/de not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2151706B1 (en) * | 1971-10-18 | 1973-05-03 | Cegla, Ulrich, Dr med , 600 0 Frank fürt Niederrad | Tantalum-contg x-ray contrast agents - in aerosol form for bronchography |
US3937800A (en) * | 1972-07-17 | 1976-02-10 | Dure Smith Peter | Bronchographic x-ray contrast method |
Non-Patent Citations (5)
Title |
---|
CA1954 * |
CA1965 * |
CA1971 * |
CA1975 * |
CA1977 * |
Also Published As
Publication number | Publication date |
---|---|
GB2001969B (en) | 1982-02-10 |
GB2001969A (en) | 1979-02-14 |
DE2831524A1 (de) | 1979-02-01 |
US4176173A (en) | 1979-11-27 |
JPS62917B2 (fr) | 1987-01-10 |
JPS5422327A (en) | 1979-02-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |