FR2382239A1 - Compose drogue-polymere absorbable et procede de preparation - Google Patents

Compose drogue-polymere absorbable et procede de preparation

Info

Publication number
FR2382239A1
FR2382239A1 FR7805876A FR7805876A FR2382239A1 FR 2382239 A1 FR2382239 A1 FR 2382239A1 FR 7805876 A FR7805876 A FR 7805876A FR 7805876 A FR7805876 A FR 7805876A FR 2382239 A1 FR2382239 A1 FR 2382239A1
Authority
FR
France
Prior art keywords
preparation
polymer compound
absorbable drug
drug
absorbable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7805876A
Other languages
English (en)
Other versions
FR2382239B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethicon Inc
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Publication of FR2382239A1 publication Critical patent/FR2382239A1/fr
Application granted granted Critical
Publication of FR2382239B1 publication Critical patent/FR2382239B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)

Abstract

L'invention concerne un composé polymère-drogue à libération continue. Selon l'invention, il comprend une drogue liée de façon covalente à un polymère d' alpha -polyester ayant des unités récurrentes de formule :
FR7805876A 1977-03-02 1978-03-01 Compose drogue-polymere absorbable et procede de preparation Granted FR2382239A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/773,449 US4328204A (en) 1977-03-02 1977-03-02 Absorbable polymer-drug compounds and method for making same

Publications (2)

Publication Number Publication Date
FR2382239A1 true FR2382239A1 (fr) 1978-09-29
FR2382239B1 FR2382239B1 (fr) 1981-07-24

Family

ID=25098301

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7805876A Granted FR2382239A1 (fr) 1977-03-02 1978-03-01 Compose drogue-polymere absorbable et procede de preparation

Country Status (9)

Country Link
US (1) US4328204A (fr)
JP (1) JPS53109930A (fr)
AU (1) AU519543B2 (fr)
CA (1) CA1094450A (fr)
DE (1) DE2809034A1 (fr)
FR (1) FR2382239A1 (fr)
GB (1) GB1574268A (fr)
NZ (1) NZ186589A (fr)
ZA (1) ZA781193B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4530840A (en) * 1982-07-29 1985-07-23 The Stolle Research And Development Corporation Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents
AT382076B (de) * 1982-10-15 1987-01-12 Chemie Linz Ag Verfahren zur herstellung von presslingen mit retardierter wirkstofffreisetzung
CH656884A5 (de) * 1983-08-26 1986-07-31 Sandoz Ag Polyolester, deren herstellung und verwendung.
US4771130A (en) * 1984-02-17 1988-09-13 William Cohen Target-entrapped drugs
CA1340581C (fr) * 1986-11-20 1999-06-08 Joseph P. Vacanti Neomorphogenese chimerique d'organes par implatation cellulaire controlee, utilisant des matrices artificielles
US6309635B1 (en) 1986-11-20 2001-10-30 Children's Medical Center Corp. Seeding parenchymal cells into compression resistant porous scaffold after vascularizing in vivo
US5804178A (en) * 1986-11-20 1998-09-08 Massachusetts Institute Of Technology Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue
NZ224549A (en) * 1987-05-29 1990-04-26 Ici Australia Operations Controlled release polymer microspheres containing at least one active agent
US5198220A (en) * 1989-11-17 1993-03-30 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5242910A (en) * 1992-10-13 1993-09-07 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5447725A (en) * 1993-06-11 1995-09-05 The Procter & Gamble Company Methods for aiding periodontal tissue regeneration
US5569468A (en) * 1994-02-17 1996-10-29 Modi; Pankaj Vaccine delivery system for immunization, using biodegradable polymer microspheres
US5417982A (en) * 1994-02-17 1995-05-23 Modi; Pankaj Controlled release of drugs or hormones in biodegradable polymer microspheres
DE9407794U1 (de) * 1994-05-11 1994-09-01 Pebüso-Betonwerke Heribert Büscher GmbH & Co, 48155 Münster Auffangwanne mit Oberflächenstruktur
US5626862A (en) 1994-08-02 1997-05-06 Massachusetts Institute Of Technology Controlled local delivery of chemotherapeutic agents for treating solid tumors
US5716404A (en) * 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
US6123727A (en) * 1995-05-01 2000-09-26 Massachusetts Institute Of Technology Tissue engineered tendons and ligaments
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US6129761A (en) * 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
US6143314A (en) * 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst
US6498153B1 (en) 1998-12-31 2002-12-24 Akzo Nobel N.V. Extended release growth promoting two component composition
US7264822B2 (en) * 2002-04-03 2007-09-04 Poly-Med, Inc. Conjugated drug-polymer coated stent
DE602006000381T2 (de) * 2005-04-28 2008-12-18 Nipro Corp., Osaka Bioabsorbierbare pharmazeutische Zusammensetzung enthaltend einen PLGA-Copolymer
WO2008089257A2 (fr) * 2007-01-16 2008-07-24 Cappella, Inc. Dispositif médical d'élution de médicaments utilisant des agents thérapeutiques polymères associés à des substrats de transglutaminase

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE653150A (fr) * 1963-09-16 1965-01-18

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679653A (en) * 1968-09-27 1972-07-25 Monsanto Co Hormonally-active reaction product of a polymer with a hormone
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3755558A (en) * 1971-02-23 1973-08-28 Du Pont Polylactide drug mixtures for topical application atelet aggregation
US4066747A (en) * 1976-04-08 1978-01-03 Alza Corporation Polymeric orthoesters housing beneficial drug for controlled release therefrom

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE653150A (fr) * 1963-09-16 1965-01-18

Also Published As

Publication number Publication date
NZ186589A (en) 1979-12-11
CA1094450A (fr) 1981-01-27
GB1574268A (en) 1980-09-03
AU3367178A (en) 1979-09-06
FR2382239B1 (fr) 1981-07-24
AU519543B2 (en) 1981-12-10
US4328204A (en) 1982-05-04
JPS53109930A (en) 1978-09-26
DE2809034A1 (de) 1978-09-07
ZA781193B (en) 1979-10-31

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