FR2397391A1 - Alpha-halogenomethyl-phenylalanines et leurs derives, leur preparation et leur utilisation comme medicaments, notamment pour traiter la maladie de parkinson ou un etat de psychose - Google Patents

Alpha-halogenomethyl-phenylalanines et leurs derives, leur preparation et leur utilisation comme medicaments, notamment pour traiter la maladie de parkinson ou un etat de psychose

Info

Publication number
FR2397391A1
FR2397391A1 FR7820516A FR7820516A FR2397391A1 FR 2397391 A1 FR2397391 A1 FR 2397391A1 FR 7820516 A FR7820516 A FR 7820516A FR 7820516 A FR7820516 A FR 7820516A FR 2397391 A1 FR2397391 A1 FR 2397391A1
Authority
FR
France
Prior art keywords
halogenomethyl
psychosis
disease
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7820516A
Other languages
English (en)
French (fr)
Other versions
FR2397391B1 (it
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merrell Toraude et Cie
Original Assignee
Merrell Toraude et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude et Cie filed Critical Merrell Toraude et Cie
Publication of FR2397391A1 publication Critical patent/FR2397391A1/fr
Application granted granted Critical
Publication of FR2397391B1 publication Critical patent/FR2397391B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
FR7820516A 1977-07-11 1978-07-10 Alpha-halogenomethyl-phenylalanines et leurs derives, leur preparation et leur utilisation comme medicaments, notamment pour traiter la maladie de parkinson ou un etat de psychose Granted FR2397391A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81424377A 1977-07-11 1977-07-11

Publications (2)

Publication Number Publication Date
FR2397391A1 true FR2397391A1 (fr) 1979-02-09
FR2397391B1 FR2397391B1 (it) 1981-02-20

Family

ID=25214519

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7820516A Granted FR2397391A1 (fr) 1977-07-11 1978-07-10 Alpha-halogenomethyl-phenylalanines et leurs derives, leur preparation et leur utilisation comme medicaments, notamment pour traiter la maladie de parkinson ou un etat de psychose

Country Status (16)

Country Link
JP (1) JPS5484544A (it)
AU (1) AU525684B2 (it)
BE (1) BE868881A (it)
CH (1) CH636846A5 (it)
DE (1) DE2828738A1 (it)
DK (1) DK309378A (it)
ES (3) ES471595A1 (it)
FR (1) FR2397391A1 (it)
GB (1) GB2005659B (it)
IE (1) IE46932B1 (it)
IL (1) IL54913A0 (it)
IT (1) IT1105534B (it)
NL (1) NL7807454A (it)
NZ (1) NZ187538A (it)
SE (1) SE7807690L (it)
ZA (1) ZA783273B (it)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007600A1 (en) * 1978-07-24 1980-02-06 Merck & Co. Inc. Alpha-difluoromethyl amino acids and pharmaceutical composition containing the same
FR2450247A1 (fr) * 1979-02-28 1980-09-26 Tamsir Ndike Wade Esters et acides aliphatiques a-amines b,b-difluores

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59481A0 (en) * 1977-07-11 1980-05-30 Merrell Toraude & Co -halomethyl amino acids
IE49522B1 (en) * 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
ZA813018B (en) * 1980-05-09 1982-05-26 Merrell Toraude & Co Fluoromethylated tyrosine methyl ester
JPS5777657A (en) * 1980-08-23 1982-05-15 Merrell Toraude & Co Manufacture of aminonitrile derivative
KR20210112320A (ko) * 2018-12-06 2021-09-14 센다 바이오사이언시즈, 인크. 트리메틸아민 생산의 억제제로서의 4급 암모늄염

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines
EP0000034A1 (en) * 1977-06-01 1978-12-20 Merck & Co. Inc. Fluorinated amines, compositions and process for preparing said compounds
FR2392958A1 (fr) * 1977-06-01 1978-12-29 Merck & Co Inc Nouveaux amino-acides fluores utiles comme medicament

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines
EP0000034A1 (en) * 1977-06-01 1978-12-20 Merck & Co. Inc. Fluorinated amines, compositions and process for preparing said compounds
FR2392958A1 (fr) * 1977-06-01 1978-12-29 Merck & Co Inc Nouveaux amino-acides fluores utiles comme medicament

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007600A1 (en) * 1978-07-24 1980-02-06 Merck & Co. Inc. Alpha-difluoromethyl amino acids and pharmaceutical composition containing the same
FR2450247A1 (fr) * 1979-02-28 1980-09-26 Tamsir Ndike Wade Esters et acides aliphatiques a-amines b,b-difluores

Also Published As

Publication number Publication date
ES478516A1 (es) 1979-07-16
IL54913A0 (en) 1978-08-31
GB2005659A (en) 1979-04-25
DE2828738A1 (de) 1979-02-01
NZ187538A (en) 1982-08-17
GB2005659B (en) 1982-02-17
IE46932B1 (en) 1983-11-02
AU525684B2 (en) 1982-11-25
FR2397391B1 (it) 1981-02-20
BE868881A (fr) 1978-11-03
IE781167L (en) 1979-01-11
ES478517A1 (es) 1979-07-16
ES471595A1 (es) 1979-10-01
IT7850230A0 (it) 1978-07-10
CH636846A5 (de) 1983-06-30
IT1105534B (it) 1985-11-04
JPS5484544A (en) 1979-07-05
DK309378A (da) 1979-01-12
ZA783273B (en) 1979-06-27
JPS6326101B2 (it) 1988-05-27
NL7807454A (nl) 1979-01-15
SE7807690L (sv) 1979-01-12
AU3731278A (en) 1980-01-03

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Legal Events

Date Code Title Description
ST Notification of lapse