FR2390447A1 - Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant - Google Patents

Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant

Info

Publication number
FR2390447A1
FR2390447A1 FR7822822A FR7822822A FR2390447A1 FR 2390447 A1 FR2390447 A1 FR 2390447A1 FR 7822822 A FR7822822 A FR 7822822A FR 7822822 A FR7822822 A FR 7822822A FR 2390447 A1 FR2390447 A1 FR 2390447A1
Authority
FR
France
Prior art keywords
morphane
trimethylbenzo
thieno
preparation
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7822822A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Made SA
Original Assignee
Laboratorios Made SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Made SA filed Critical Laboratorios Made SA
Publication of FR2390447A1 publication Critical patent/FR2390447A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne l' alpha -2,5,9-triméthylbenzo-Øbõ-thiéno-Ø2,3-fõ-morphane et ses sels d'addition d'acides acceptables du point de vue pharmacologique. Elle concerne également la préparation de ces composés à partir de la 2-(3-benzo-Øbõ-thiénylméthyl)-1,3,4-triméthyl-1,2,5,6-tétrahydropyridine. Les nouveaux composés de l'invention sont doués de propriétés analgésiques.
FR7822822A 1977-02-25 1978-08-02 Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant Withdrawn FR2390447A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES456280A ES456280A1 (es) 1977-02-25 1977-02-25 Un procedimiento para la obtencion de alfa-2,5,9-trimetil- benzo(b)tieno(2,3-f)morfano.

Publications (1)

Publication Number Publication Date
FR2390447A1 true FR2390447A1 (fr) 1978-12-08

Family

ID=8473229

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7805354A Withdrawn FR2381774A1 (fr) 1977-02-25 1978-02-24 Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant
FR7822822A Withdrawn FR2390447A1 (fr) 1977-02-25 1978-08-02 Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7805354A Withdrawn FR2381774A1 (fr) 1977-02-25 1978-02-24 Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant

Country Status (11)

Country Link
US (1) US4172201A (fr)
JP (1) JPS53121797A (fr)
AR (1) AR216125A1 (fr)
AT (1) AT356295B (fr)
BE (1) BE864027A (fr)
DE (1) DE2806252C3 (fr)
ES (1) ES456280A1 (fr)
FR (2) FR2381774A1 (fr)
GB (1) GB1566846A (fr)
NL (1) NL7801480A (fr)
PT (1) PT67699B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281130A (en) * 1979-05-24 1981-07-28 Sterling Drug Inc. Lower-alkyl 4,6,7,8,8a-9-hexahydro-6,9-ethanothieno[3,2-f]indolizine-10-carboxylate
US4587253A (en) * 1984-07-30 1986-05-06 Merck & Co., Inc. Bridged pyridine compounds useful as calcium channel blockers and analgesics
US4591587A (en) * 1984-10-01 1986-05-27 Merck & Co., Inc. Cyclopropyl pyridine compounds useful as calcium channel blockers
US4590276A (en) * 1984-10-01 1986-05-20 Merck & Co., Inc. Process for the preparation of cyclopropyl pyridine compounds useful as calcium channel blockers
US4599341A (en) * 1984-10-01 1986-07-08 Merck & Co., Inc. Substituted and bridged pyridines useful as calcium channel blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3382249A (en) * 1964-10-20 1968-05-07 Sterling Drug Inc 1, 2, 3, 4, 5, 6-hexahydro-3-(cycloalkyl-lower alkylene-)-2, 6-methano-3-naphth [2, 1-f]azocines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/74 *

Also Published As

Publication number Publication date
DE2806252B2 (de) 1981-01-08
AT356295B (de) 1980-04-25
GB1566846A (en) 1980-05-08
DE2806252C3 (de) 1981-10-08
AR216125A1 (es) 1979-11-30
ES456280A1 (es) 1978-04-16
FR2381774A1 (fr) 1978-09-22
JPS53121797A (en) 1978-10-24
PT67699A (en) 1978-03-01
DE2806252A1 (de) 1978-08-31
PT67699B (en) 1980-05-05
ATA136678A (de) 1979-09-15
US4172201A (en) 1979-10-23
NL7801480A (nl) 1978-08-29
BE864027A (fr) 1978-08-16

Similar Documents

Publication Publication Date Title
FR2370723A1 (fr) Nouveaux aryl-acylamides n-(2-aminocycloaliphatiques), leur procede de preparation et medicament les contenant
MA20380A1 (fr) Procede de production d'un 2-oxindole-1-carboxamide et produit obtenu
MA26733A1 (fr) Derives d'isothiazole nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2354992A1 (fr) Nouvelles 4-amino-4-arylcyclohexanones, leur procede de preparation et medicament les contenant
LU90317I2 (fr) Tacrolimus et ses sels et dérivés pharmaceutiquement acceptables
FR2370722A1 (fr) Nouveaux benzamides trans-n-(2-aminocycloaliphatiques), leur procede de preparation et medicament les contenant
FR2378763A1 (fr) Nouveaux derives de 1,4-dihydropyridine substitues en position 2, leur procede de preparation et medicament les contenant
KR900006341A (ko) 이형고리 화합물
PT98734A (pt) Processo de preparacao de compostos 1,2,5,6-tetra-hidropiridina e de composicoes farmaceuticas que os contem
FR2362834A1 (fr) Nouveaux derives 6-hemicetal ou 6-ceto de prostaglandine, leur procede de preparation et medicament les contenant
FR2386527A1 (fr) Nouvelles 2-alkyleneaminodihydropyridines, leur procede de preparation et medicament les contenant
FR2397403A1 (fr) Nouveaux derives de 1-acyl 2-cyano-aziridine, procede pour leur preparation et compositions pharmaceutiques contenant ces composes
FR2374307A1 (fr) Derives de la 1,4-dihydropyridine, leur procede d'obtention et composition pharmaceutique les contenant
FR2424908A1 (fr) Nouveaux analogues de prostacycline, leur procede de production et medicament les contenant
BE1002788A3 (fr) Composition pharmaceutique contenant un extrait vegetal et procede pour sa preparation.
FR2403330A1 (fr) Nouveaux derives de benzoyl-2-chloro-4-glycinanilides substitues, leur procede de preparation et leur application en tant que medicaments
KR840001553B1 (ko) 시클로헥센 유도체의 제조방법
FR2390447A1 (fr) Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant
FR2375222A1 (fr) Nouveaux composes du type (2-benzothiazolyl)oxamate, leur procede de preparation et medicament les contenant
FR2395272A1 (fr) Nouveaux medicaments derives de l'acide amidinopenicillanique
FR2392023A1 (fr) Nouveaux trans-5-aryl-2,3,4,4a,5,9,b-hexahydro-1h-pyrido (4,3-b) indoles, leur procede de preparation et composition pharmaceutique les contenant
FR2536751B1 (fr) Nouveaux derives de tricyclophosphazenes, procede pour leur preparation et leur application en tant que medicament
EA199700287A1 (ru) Бензамиды для лечения нейродегенеративных заболеваний
FR2401132A1 (fr) Nouveaux derives de triphenylbutene-1, leur procede de production et composition pharmaceutique les contenant
FR2440353A1 (fr) Nouveaux arylethanols, leurs procedes d'obtention et leur emploi comme medicament

Legal Events

Date Code Title Description
ST Notification of lapse