FR2381774A1 - Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant - Google Patents

Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant

Info

Publication number
FR2381774A1
FR2381774A1 FR7805354A FR7805354A FR2381774A1 FR 2381774 A1 FR2381774 A1 FR 2381774A1 FR 7805354 A FR7805354 A FR 7805354A FR 7805354 A FR7805354 A FR 7805354A FR 2381774 A1 FR2381774 A1 FR 2381774A1
Authority
FR
France
Prior art keywords
morphane
trimethylbenzo
thieno
preparation
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7805354A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Made SA
Original Assignee
Laboratorios Made SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Made SA filed Critical Laboratorios Made SA
Publication of FR2381774A1 publication Critical patent/FR2381774A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne l' alpha -2,5,9-triméthylbenzo-Øbõ-thiéno-Ø2,3-fõ-morphane, et à titre de composé intermédiaire, la 2-(3-benzo-Øbõ-thienylméthyl)-1,3,4-triméthyl-1,2,5,6-tétra-hydropyridine, et leurs sels d'addition d'acides acceptables du point de vue pharmacologique. Elle concerne également la préparation de ces composés. Les nouveaux composés de l'invention sont doués de propriétés analgésiques.
FR7805354A 1977-02-25 1978-02-24 Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant Withdrawn FR2381774A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES456280A ES456280A1 (es) 1977-02-25 1977-02-25 Un procedimiento para la obtencion de alfa-2,5,9-trimetil- benzo(b)tieno(2,3-f)morfano.

Publications (1)

Publication Number Publication Date
FR2381774A1 true FR2381774A1 (fr) 1978-09-22

Family

ID=8473229

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7805354A Withdrawn FR2381774A1 (fr) 1977-02-25 1978-02-24 Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant
FR7822822A Withdrawn FR2390447A1 (fr) 1977-02-25 1978-08-02 Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7822822A Withdrawn FR2390447A1 (fr) 1977-02-25 1978-08-02 Procede de preparation de l'a-2,5,9-trimethylbenzo-(b)-thieno-(2,3-f)-morphane, produit obtenu et composition pharmaceutique le contenant

Country Status (11)

Country Link
US (1) US4172201A (fr)
JP (1) JPS53121797A (fr)
AR (1) AR216125A1 (fr)
AT (1) AT356295B (fr)
BE (1) BE864027A (fr)
DE (1) DE2806252C3 (fr)
ES (1) ES456280A1 (fr)
FR (2) FR2381774A1 (fr)
GB (1) GB1566846A (fr)
NL (1) NL7801480A (fr)
PT (1) PT67699B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281130A (en) * 1979-05-24 1981-07-28 Sterling Drug Inc. Lower-alkyl 4,6,7,8,8a-9-hexahydro-6,9-ethanothieno[3,2-f]indolizine-10-carboxylate
US4587253A (en) * 1984-07-30 1986-05-06 Merck & Co., Inc. Bridged pyridine compounds useful as calcium channel blockers and analgesics
US4591587A (en) * 1984-10-01 1986-05-27 Merck & Co., Inc. Cyclopropyl pyridine compounds useful as calcium channel blockers
US4590276A (en) * 1984-10-01 1986-05-20 Merck & Co., Inc. Process for the preparation of cyclopropyl pyridine compounds useful as calcium channel blockers
US4599341A (en) * 1984-10-01 1986-07-08 Merck & Co., Inc. Substituted and bridged pyridines useful as calcium channel blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3382249A (en) * 1964-10-20 1968-05-07 Sterling Drug Inc 1, 2, 3, 4, 5, 6-hexahydro-3-(cycloalkyl-lower alkylene-)-2, 6-methano-3-naphth [2, 1-f]azocines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/74 *

Also Published As

Publication number Publication date
BE864027A (fr) 1978-08-16
ATA136678A (de) 1979-09-15
PT67699B (en) 1980-05-05
DE2806252B2 (de) 1981-01-08
FR2390447A1 (fr) 1978-12-08
AT356295B (de) 1980-04-25
US4172201A (en) 1979-10-23
NL7801480A (nl) 1978-08-29
AR216125A1 (es) 1979-11-30
JPS53121797A (en) 1978-10-24
ES456280A1 (es) 1978-04-16
DE2806252A1 (de) 1978-08-31
DE2806252C3 (de) 1981-10-08
PT67699A (en) 1978-03-01
GB1566846A (en) 1980-05-08

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Legal Events

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